The fecal microbiota transplantation fmt market has seen considerable growth due to a variety of factors.
• The market size for fecal microbiota transplantation (FMT) has been expanding considerably in the past years. It is predicted to rise from $0.85 $ billion in 2024 to $0.91 $ billion in 2025, experiencing a compound annual growth rate (CAGR) of 7.2%.
The substantial growth during this historic period can be credited to the rising awareness of gut microbiome, broadening therapeutic applications, an increase in personalized medicine, the adoption in gastroenterology practices, a growing number of clinical trials, and an escalation in funding and investments.
The fecal microbiota transplantation fmt market is expected to maintain its strong growth trajectory in upcoming years.
• The market size for fecal microbiota transplantation (FMT) is projected to witness robust growth in the coming years, increasing to $1.19 billion in 2029 with a compound annual growth rate (CAGR) of 6.9%.
This growth anticipated in the forecast period is linked to a rising number of clostridium difficile infections (CDI), growing instances of inflammatory bowel diseases, enhanced research and development initiatives, an expanding elderly population, and improvements in healthcare infrastructure. Key trends for this forecast period include the establishment of standardized protocols for donor screening and stool preparation, advancements in microbiome analysis, upgrades in stool processing technologies, novel methods of delivery, and the creation of synthetic or standardized microbiota-based products.
The growth of the fecal microbiota transplantation (FMT) market is anticipated to be fueled by the increasing incidence of gastrointestinal disorders. Gastrointestinal (GI) disorders are a broad spectrum of conditions that impact the digestive tract, encompassing the esophagus, stomach, small and large intestines (colon), rectum, and anus. The rise in these disorders can be attributed to increased stress levels, inactive lifestyles, and a higher intake of processed foods. FMT is utilized in the treatment of GI disorders to replenish healthy gut bacteria, especially in cases of recurrent Clostridioides difficile infections. For example, the number of people in Canada with IBD is expected to surge rapidly between 2023 and 2035, as per Crohn's and Colitis Canada, a non-profit organization based in Canada. The figures are projected to go up from 322,600 in 2023 (0.8% of the population) to 470,000 in 2035 (1.1% of the population). In 2023, around 11,000 people will be diagnosed (1 every 48 minutes), and this number is predicted to reach 14,000 by 2035 (1 every 38 minutes). As such, the escalating occurrence of gastrointestinal disorders is leading to the expansion of the fecal microbiota transplantation (FMT) market.
The fecal microbiota transplantation (FMT) market covered in this report is segmented –
1) By Type: Fermentation, Fresh, Cryopreservation
2) By Donor Type: Stool-Derived, Fecal-Derived, Whole-Microbiome Derived
3) By Indication: Clostridioides Difficile Infection, Inflammatory Bowel Disease, Metabolic Syndrome, Other Indications
4) By Administration Route: Oral, Rectal, Nasogastric, Colon Capsule
5) By End-User: Hospitals, Specialty Clinics, Other End-Users
Subsegments:
1) By Fermentation: Fermented FMT Products, Fermented Capsules, Fermented Liquids, In-House Fermentation Techniques
2) By Fresh: Fresh Stool Samples, Fresh FMT Capsules, Fresh FMT Solutions for In-Hospital Use, Freshly Prepared FMT for Outpatient Use
3) By Cryopreservation: Cryopreserved Stool Samples, Cryopreserved FMT Capsules, Cryopreserved Liquid FMT, Long-Term Storage Solutions for Cryopreserved FMT
Leading entities in the fecal microbiota transplantation (FMT) market are concentrating on the creation of novel solutions like microbiota-based live biotherapeutics to improve the effectiveness of treatments for gastrointestinal conditions. These refer to live microbes that serve as therapeutic agents to alter or replenish the gut microbiome for disease treatment. For example, Ferring Pharmaceuticals, a Swiss biopharmaceutical firm, gained US Food and Drug Administration (FDA) clearance in November 2022 for REBYOTA (fecal microbiota, live-jslm), an innovatory first-of-its-kind microbiota-based live biotherapeutic. This is designed to prevent the reoccurrence of Clostridioides difficile infection (CDI) in those aged 18 or above, post-antibiotic treatment for recurrent CDI. REBYOTA is prescribed for preventing recurrence of C. difficile infection in individuals of 18 years of age and older who have undergone antibiotic therapy for recurrent CDI.
Major companies operating in the fecal microbiota transplantation (FMT) market are:
• Ferring Pharmaceuticals
• Johns Hopkins Medicine
• Seres Therapeutics
• Taconic Biosciences
• Enterome
• Rebiotix Inc.
• Finch Therapeutics Group Inc.
• Locus Biosciences
• Yeda Research and Development Co. Ltd.
• Microbiotica Limited
• CosmosID Inc.
• AOBiome
• Synthetic Biologics Inc.
• Osel Inc.
• OpenBiome
• Asia Microbiota Bank
• Taymount Clinic
• MicroBiome Therapeutics LLC
• MaaT Pharma SA
• Kallyope
North America was the largest region in the fecal microbiota transplantation (FMT) market in 2024. The regions covered in the fecal microbiota transplantation (FMT) market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.