What Has Driven the Growth of the Human Liver Model Market in Recent Years?
The human liver model market has seen considerable growth due to a variety of factors.
•The market size for human liver models has seen substantial growth in the past few years. The market value is projected to increase from $2.34 billion in 2024 to $2.63 billion in 2025, maintaining a compound annual growth rate (CAGR) of 12.2%.
The significant growth observed in the historic period can be linked to factors such as the need for drug development, progress in biotechnology, alternatives to animal testing, a rise in liver diseases, and regulatory requirements.
What is the Market Size Forecast for the Human Liver Model Market?
The human liver model market is expected to maintain its strong growth trajectory in upcoming years.
• The market size of the human liver model is predicted to experience swift expansion in several coming years. The prediction states that the market will expand to $4.41 billion by 2029 with a compound annual growth rate (CAGR) of 13.8%.
This potential growth during the forecast period can be credited to various factors such as the incorporation of AI and machine learning, the emergence of patient-derived liver models, bioengineering advancements, drug safety measures, and toxicity testing norms, along with virtual clinical trials. The forecast period is likely to witness significant trends like the integration of multi-organ models, innovation in 3D bioprinting, the capacity for high-throughput screening, enhanced vascularization, improved blood flow, and adherence to ethical and regulatory norms.
What Are The Core Factors Supporting Growth In The Human Liver Model Market?
An upward trend in liver disease incidences is anticipated to stimulate the expansion of the human liver model market. A liver disease is any anomaly in the liver that hinders its normal function or prevents it from operating efficiently. The utilization of human liver models, a budding field of research, has the potential to enhance our understanding of liver diseases and aid in drug development. Consequently, an increase in the incidence of liver diseases is hastening the growth of the human liver model market. For example, Caner Australia, a governmental cancer entity situated in Australia, reported that approximately 2,905 new cases of liver cancer were identified in Australia in 2022, comprising 2,113 males and 792 females. Moreover, the likelihood of developing liver cancer by age 85 is projected to be 1 in 103 (or 0.97%) in 2022, 1 in 70, or 1.4%, for men, and 1 in 195, or 0.51%, for women. Consequently, the increasing prevalence of liver diseases is driving the growth of the human liver model market.
What Are The Major Segments Within The Global Human Liver Model Market?
The human liver model market covered in this report is segmented –
1) By Product: Liver Organoids, Liver-On-A-Chip, 2D Models, Animal Models, 3D Bioprinting
2) By Application: Educational, Drug Discovery, Other Applications
3) By End Users: Research Institutes, Pharmaceutical Companies, Other End Users
Subsegments:
1) By Liver Organoids: Primary Liver Organoids, Induced Pluripotent Stem Cell (iPSC)-Derived Organoids
2) By Liver-On-A-Chip: Microfluidic Liver Chips, Multi-Organ Chip Systems
3) By 2D Models: Liver Cell Cultures, Liver Cell Lines
4) By Animal Models: Rodent Models, Large Animal Models
5) By 3D Bioprinting: Bioprinted Liver Tissues, Hybrid Bioprinted Models
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Which Trends Are Expected To Transform The Human Liver Model Market?
A key trend that is becoming increasingly prevalent in the human liver model market is product innovation. This is primarily because large businesses in the market are focusing on developing original products in order to reinforce their market position. For example, in April 2023, LifeNet Health Life Sciences, an organization based in the US providing human cell and tissue-based solutions, unveiled TruVivo, an entirely human cell-based revolutionary liver system, which will facilitate crucial drug and compound research and development. This novel 2D+ solution amalgamates the comprehensive data associated with 3D models with the adaptability and straightforwardness of a 2D model.
Who Are the Key Players in the Human Liver Model Market?
Major companies operating in the human liver model market include:
• Corning Incorporated
• EISCO Scientific LLC
• BioIVT LLC
• Cyprotex plc
• Emulate Inc.
• Cellink AB
• Nortis Inc.
• InSphero AG
• CN Bio Innovations Ltd.
• TissUse GmbH
• Ascendance Biotechnology Inc.
• HemoShear Therapeutics Inc.
• Cyfuse Biomedical
• MIMETAS BV
• Biopredic International Sarl
• ZenBio
• Hurel Corporation
• Regenovo
• Pandorum
• Organovo Holdings Inc.
• BICO Group
• Hepregen Corporation
• Kirkstall Ltd.
• HepaLife Technologies Inc.
• Cellaïon SA.
What Is The Most Dominant Region In The Human Liver Model Market?
North America was the largest region in the human liver model market in 2024. The regions covered in the human liver model market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
