The intravenous immunoglobulin market has seen considerable growth due to a variety of factors.
• The market for intravenous immunoglobulin has seen robust growth in the past few years. The market is projected to experience an increase from $14.66 billion in 2024 to $15.72 billion in 2025, resulting in a compound annual growth rate (CAGR) of 7.2%. The strong historic growth has been influenced by factors such as the treatment of primary immunodeficiency disorders, handling of neurological disorders, the escalation of the aged population, advancements in the technology for plasma fractionation, the expanded applications in neurology, treatments for infectious diseases, and care of pediatric immunodeficiency.
The Intravenous Immunoglobulin market is expected to maintain its strong growth trajectory in upcoming years.
• Expectations are high for robust growth in the intravenous immunoglobulin market in the forthcoming years. It is projected to expand to $22.01 billion in 2029, with a compound annual growth rate (CAGR) of 8.8%.
This growth during the forecasted period is attributed to factors such as the rising cases of autoimmune diseases, continuous research in immunology, an increase in healthcare spending, a surge in cancer cases, advancements in immunoglobulin products, and the introduction of personalized medicinal practices. The primary trends driving this growth forecast include the treatment of primary immunodeficiency disorders (PIDD), rapid advancements in technology, strategic collaborations and partnerships, improved manufacturing processes, emerging indications in neurology, usage in hematology, and advances in immunotherapy.
The escalation in the number of elderly individuals is anticipated to propel the advancement of the intravenous immunoglobulin market. The term elderly population is used to describe those aged 65 and above. With age, the immune system weakens and the body's supply of antibodies decreases, necessitating the need for immunoglobulins. This subsequently elevates the demand for intravenous immunoglobulins, thereby boosting the intravenous immunoglobulin market. For example, data obtained by the Population Reference Bureau, a Kenya-based nonprofit organization, in January 2024 stipulated that the American population aged 65 and above is projected to increase from 58 million in 2022 to 82 million by 2050, marking a 47% growth. The percentage of this age group within the overall population is also estimated to escalate from 17% to 23% over the same period. Consequently, the expanding elderly population is set to spur the growth of the intravenous immunoglobulin market.
The intravenous immunoglobulin market covered in this report is segmented –
1) By Type: IgG (Immunoglobulin G), IgM (Immunoglobulin M), IgA (Immunoglobulin A), IgE (Immunoglobulin E), IgD (Immunoglobulin D)
2) By Distribution Channel: Hospital Pharmacy, Retail Pharmacy, Other Distribution Channels
3) By Application: Hypogammaglobulinemia, Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), Primary Immunodeficiency Diseases, Myasthenia Gravis, Multifocal Motor Neuropathy, Other Applications
4) By End-User: Hospitals, Clinics, Home Care
Subsegments:
1) By Immunoglobulin G (IgG): Normal IgG, Specific IgG
2) By Immunoglobulin M (IgM): Normal IgM, Specific IgM
3) By Immunoglobulin A (IgA): Normal IgA, Specific IgA
4) By Immunoglobulin E (IgE): Normal IgE, Specific IgE
5) By Immunoglobulin D (IgD): Normal IgD, Specific IgD
The increasing trend of product innovation is becoming more prevalent in the intravenous immunoglobulin market. Major market players are centering their strategy around the development of new products, like liquid immune globulin formulations, for treating immunodeficiency diseases and maintaining their market presence. For example, in December 2023, GC Pharma, a pharmaceutical company based in South Korea, introduced Alyglo, approved by the US Food and Drug Administration (FDA). Alyglo is a sterile, 10% immunoglobulin G (IgG) liquid formulation, which offers 100 mg/mL of protein, and a minimum of 96% originates from human IgG derived from collective human plasma. The drug is specifically meant for adults 17 years and older suffering from primary humoral immunodeficiency (PI). This includes illnesses like congenital agammaglobulinemia, common variable immunodeficiency (CVID), Wiskott-Aldrich syndrome, and severe combined immunodeficiency (SCID).
Major companies operating in the intravenous immunoglobulin market include:
• Bio Products Laboratory Limited
• Biotest AG
• China Biologic Products Holdings Inc.
• CSL Behring
• Grifols S.A.
• Kedrion SpA
• Shanghai RAAS Blood Products Co. Ltd.
• Octapharma AG
• Takeda Pharmaceutical Company Limited
• Baxter International Inc.
• LFB Biotechnologies SAS
• BDI Pharma Inc.
• Hualan Biological Engineering Inc.
• ADMA Biologics Inc.
• Bharat Serums and Vaccines Limited
• Sanquin Plasma Products B.V.
• Prothya Biosolutions B.V.
• Sichuan Yuanda Shuyang Pharmaceutical Co. Ltd.
• Pfizer Inc.
• Kedrion Biopharma
• Intas Pharmaceuticals
• Octapharma Pharmazeutika Produktionsges.m.b.H.
• GC Pharma
• Grifols Biologicals Inc.
• Kamada Ltd.
• LFB USA
• Octapharma Plasma Inc.
• Panacea Biotec Ltd.
North America was the largest region in the intravenous immunoglobulin market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the intravenous immunoglobulin market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.