The protein a resin market has seen considerable growth due to a variety of factors.
• The size of the protein A resin market has significantly increased in the past few years. Its value will increase from $1.66 billion in 2024 to $1.8 billion in 2025, experiencing a compound annual growth rate (CAGR) of 8.6%. The expansion in the historic duration was driven by the rise in biopharmaceutical production, the growing acceptance of monoclonal antibodies, wider research and development initiatives, regulatory focus on the quality of biopharmaceuticals, and an increase in chronic diseases.
The Protein A Resin market is expected to maintain its strong growth trajectory in upcoming years.
• The market for protein A resin is set to experience rapid expansion in the coming years. The volume of this market is projected to escalate to $2.66 billion by 2029, growing at a compound annual growth rate (CAGR) of 10.3%.
This surge during the forecast years can be ascribed to factors like increased biosimilar creation, emphasis on cost-effectiveness, rising investments in bioprocessing infrastructure, the proliferation of the biopharmaceutical sector in developing economies, and an escalating need for personalized medication. Primary trends within the forecast tenure encompass singular-use systems, technology advancements, demand from emerging markets, strategic collaborations, partnerships, and an emphasis on eco-friendly practices.
The protein A resin market is expected to expand due to enhanced R&D investments within the pharmaceutical sector. The research and development (R&D) processes include the discovery and creation of novel drugs, therapies, technologies or services aimed at enhancing patient health. Protein A resin plays a key role in various chromatography assays employed in pharmaceutical development processes, where it is utilized as a chromatography medium. For example, Roche Holding AG, a pharmaceutical company based in Switzerland, recorded their highest R&D expense in 2022 at $16.79 billion, representing a 3.7% increase from 2021. In addition, in 2022, Merck, a pharmaceutical firm from the US, raised its R&D expenditure by 10% relative to 2021, reaching $13.54 billion. Thus, the escalation in R&D investments in pharmaceutical firms is driving the protein A resin market's growth.
The protein A resin market covered in this report is segmented –
1) By Type: Natural Protein A, Recombinant Protein A
2) By Matrix Type: Agarose-Based Protein A, Glass Or Silica-Based Protein A, Organic Polymer-Based Protein A
3) By Application: Antibody Purification, Immunoprecipitation
4) By End User: Biopharmaceutical Manufacturers, Clinical Research Laboratories, Academic Institutes
Subsegments:
1) By Natural Protein A: Affinity Chromatography Resins, Protein Purification Resins, IgG Binding Resins
2) By Recombinant Protein A: Genetically Engineered Protein A Resins, Modified Protein A Resins, High-Capacity Protein A Resins
Major players in the protein A resin market are concentrating on product advancements, such as high-performance affinity protein A resin, with the aim to amplify purification efficiency, diminish production expenses, and boost overall yields in biopharmaceutical manufacturing. The high-performance affinity Protein A resin is a unique chromatography medium fashioned for the competent purification of antibodies and other proteins from intricate biological mixtures. For instance, in July 2024, Purolite, Ltd., a company based in the US that develops, manufactures, and supplies resins, introduced DurA Cycle A50, a novel affinity Protein A resin aimed at improving downstream purification in the biologics sector. This pioneering resin allows for an extended resin lifespan, lesser ligand leakage, and high efficiency, positioning it as a cost-effective solution for antibody purification. The introduction of this product tackles critical industry problems such as cost reduction and assurance of supply chain security through dual sourcing, thereby assuring increased efficiency for clients.
Major companies operating in the protein A resin market include:
• GenScript Biotech Corporation
• Agilent Technologies Inc.
• Repligen Corporation
• Thermo Fisher Scientific Inc.
• Bio-Rad Laboratories Inc.
• Abcam plc
• Novasep Holdings SAS
• GE Healthcare Technologies Inc.
• Merck KGaA
• Tosoh Bioscience LLC
• Purolite Corporation
• Kaneka Corporation
• JSR Life Sciences Corporation
• Danaher Corporation
• Avantor Inc.
• Global Life Sciences Solutions USA
• EMD Millipore Corp.
• Bio-Works Technologies AB
• Avantor Performance Materials LLC
• Avacta Life Sciences Limited
• Purolite Lifesciences
North America was the largest region in the Protein A Resin market in 2024. Europe is expected to be the fastest-growing region in the protein A resin market report during the forecast period. The regions covered in the protein A resin market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa