The restless leg syndrome market has seen considerable growth due to a variety of factors.
• The market size for restless leg syndrome has seen a significant increase in recent times. Predictions suggest that it will rise from $1.91 billion in 2024 to $2.17 billion in 2025, demonstrating a compound annual growth rate (CAGR) of 13.8%.
The historical growth can be credited to several factors, such as higher alcohol consumption rates, an increase in health insurance coverage, the availability of over-the-counter drugs, the rise in public health measures and a spike in mental health problems.
The restless leg syndrome market is expected to maintain its strong growth trajectory in upcoming years.
• The market for restless leg syndrome is poised for noteworthy expansion in the coming years, potentially reaching a worth of $3.59 billion in 2029 with a Compound Annual Growth Return (CAGR) of 13.4%.
The projected growth within this period is largely due to factors like an upsurge in healthcare spending, heightened awareness efforts, higher rates of early detection, increased government financial support, and more robust participation in clinical trials. The era forecasted will also be marked by significant trends such as AI-assisted personalized treatment strategies, advanced neurostimulation devices, the use of deep learning algorithms for disease diagnosis, brainwave modulation technology, and the application of wearable exoskeletons for leg movement regulation.
The escalating rates of iron deficiency are projected to fuel the expansion of the restless leg syndrome market. Iron deficiency is a health issue where the body is unable to generate enough healthy red blood cells due to a lack of iron, resulting in symptoms like fatigue, weakness, and pale skin. The upsurge in iron deficiency cases stems from factors such as inadequate dietary consumption, blood loss, malabsorption disorders, and heightened iron needs during pregnancy or growth phases. Handling of restless leg syndrome generally entails iron supplementation or dietary modifications, which not only offer relief from the uncomfortable urges and sensations but also work towards addressing the root cause of the iron deficiency by replenishing the body's iron reserves, promoting the production of red blood cells and re-establishing normal neurological function. For example, the National Health Service England, a government agency based in England, reported that in the period of 2023-24 there were 191,927 admissions due to iron deficiency, marking a rise of 11% in comparison with 2022-23. Therefore, the escalating rates of iron deficiency are supporting the growth of the restless leg syndrome market.
The restless leg syndrome market covered in this report is segmented –
1) By Type: Primary Restless Legs Syndrome, Secondary Restless Legs Syndrome
2) By Treatment Type: Medicine And Devices, Surgery
3) By Route Of Administration: Oral, Injectable
4) By Distribution Channel: Hospital Pharmacy, Retail Pharmacy, Online Pharmacy
5) By Application: Neurological Treatment, Sleep Disorders, Movement Disorders, Symptom Management
Subsegments:
1) By Primary Restless Legs Syndrome: Idiopathic Restless Legs Syndrome, Hereditary Restless Legs Syndrome
2) By Secondary Restless Legs Syndrome: Iron Deficiency-related Restless Legs Syndrome, Chronic Kidney Disease-related Restless Legs Syndrome, Pregnancy-related Restless Legs Syndrome, Medication-induced Restless Legs Syndrome
Leading businesses in the restless leg syndrome (RLS) market are concentrating on developing groundbreaking solutions, such as innovative non-invasive treatments, to enhance the management of symptoms and improve patient results. Innovative non-invasive treatments are defined as novel medical therapies that do not involve surgery or skin penetration. They aim to offer relief from various medical conditions using advanced techniques such as electrical stimulation, light therapy, or external devices. For example, in April 2023, Varco Leg Care, a health-technology company from India, earned FDA De Novo approval for its NTX100 Tonic Motor Activation (TOMAC) System. This system is engineered to manage moderate to severe symptoms of restless legs syndrome (RLS) and boost the quality of sleep in patients who don't find medicines effective. It functions by electrically stimulating the peroneal nerves within both sides of the body to initiate tonic, continuous muscle activity, which doesn't interfere with sleep. This stimulation aids in mitigating the symptoms of RLS.
Major companies operating in the restless leg syndrome market are:
• Pfizer Inc.
• Roche Holding AG
• Merck & Co Inc.
• Novartis International AG
• GlaxoSmithKline plc
• Teva Pharmaceutical Industries Ltd.
• Boehringer Ingelheim International GmbH
• Baxter International Inc.
• Astellas Pharma Inc.
• UCB S.A.
• Kyowa Kirin Co Ltd.
• Amneal Pharmaceuticals Inc.
• Lupin Pharmaceuticals Inc.
• Alembic Pharmaceuticals Limited
• Mundipharma International Limited
• Azurity Pharmaceuticals LLC
• Otsuka Pharmaceutical Co Ltd.
• Horizon Therapeutics plc
• Mylan N.V.
• Apollo Pharmacy Limited
Europe was the largest region in the restless leg syndrome market in 2024. North-America is expected to be the fastest-growing region in the forecast period. The regions covered in the restless leg syndrome market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.