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Global TCR Therapy Opportunities 2025, Forecast To 2034

24 Mar, 2025

What Is The Current and Historic Market Size Analysis Of The TCR Therapy Market?

The tcr therapy market has seen considerable growth due to a variety of factors.
• The market size for TCR therapy has seen a swift expansion in the recent past. The market worth is projected to rise from $0.18 billion in 2024 to $0.26 billion in 2025, with a compounding yearly growth rate (CAGR) of 40.3%.
This growth during the historical phase can be credited to the rising cancer cases, a surge in the attention towards immunotherapy, positive outcomes from clinical trials, and ample monetary backing from investors.

What Is The Forecast For The TCR Therapy Market Size?

The tcr therapy market is expected to maintain its strong growth trajectory in upcoming years.
• Expectations for the TCR therapy market size in the years to follow point towards significant expansion. Predictions suggest it will appreciate to a value of $0.87 billion in 2029, sustained by a compound annual growth rate (CAGR) of 35.4%.
This predicted expansion in the forecasted timeframe is supported by an upsurge in ongoing clinical trials, advancements in healthcare technology, wider usage in solid tumors, regulatory backing and expedited approval processes, and integration with complementary therapies. Key trends in the forecast period include solid tumor extension, next-generation TCR engineering, heightened personalization and neoantigen identification, global alliances and strategic affiliations, ongoing research in immunology and tumor biology.

What Are The Essential Drivers Behind The Growth Of The TCR Therapy Market?

The TCR therapy market is poised for growth as the incidence of cancer continues to rise. Cancer, defined as a collection of diseases marked by the uninhibited growth and spread of abnormal bodily cells, can invade and damage healthy tissues and disrupt organ function. Numerous factors contribute to its emergence, including lifestyle choices, aging, obesity, and genetics. T-cell receptor (TCR) therapy is a promising cancer treatment approach that leverages the immune system's power to specifically target and enhance the efficacy of TCR therapy. This was evidenced in October 2022 when the UK-based healthcare charity, Macmillan Cancer Support, reported that the number of people with cancer was 3 million in 2020 and projected to increase to 3.5 million by 2025, 4 million by 2030, and 5.3 million by 2040. Given this, the escalating prevalence of cancer is a significant driver for the TCR therapy market's expansion.

How Is The Global TCR Therapy Market Divided Into Key Segments?

The TCR therapy market covered in this report is segmented –
1) By Product Type: Infusions, Injectables, Other Product Types
2) By Indication: Leukemia, Lymphoma, Myeloma, Other Indication
3) By Distribution Channel: Online, Offline
4) By End-User: Hospital Pharmacy, Retail Pharmacy, Specialty Clinics Subsegments:
1) By Infusions: Autologous TCR Infusions, Allogeneic TCR Infusions
2) By Injectables: TCR-based Injectable Formulations, Injectable TCR Gene Therapies
3) By Other Product Types: TCR-Engineered Cell Therapies, TCR Combination Therapies with Other Immunotherapies, TCR-Based Biologics

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How Are New Trends Impacting The Size Of The TCR Therapy Market?

In an effort to gain a competitive advantage and provide critical treatments to patients, leading businesses in the TCR therapy market are actively engaging in strategic partnerships. These alliances involve combining their individual resources and strengths to achieve collective growth and success. A case in point is the alliance struck in December 2023 between US-based biotech entity, ImmunoScape, and Singapore-based pharmaceutical firm, the Experimental Drug Development Centre (EDDC). Their joint goal is to generate novel TCR-based bispecific molecules for solid tumors. The collaboration intends to capitalize on ImmunoScape's proficiency in systems immunology and computational biology, in conjunction with EDDC's capabilities, to push forward research in the area. Their strategic partnership aims to utilize their distinct fortes to hasten the production of increasingly effective and affordable cancer treatments.

Who Are the Key Players In The TCR Therapy Market?

Major companies operating in the TCR therapy market are:
• Pfizer Inc.
• Johnson & Johnson Services Inc.
• Novartis AG
• Bristol Myers Squibb Company
• GlaxoSmithKline PLC
• Gilead Sciences Inc.
• Bluebird bio Inc.
• Immunocore Limited
• Immatics N.V.
• Poseida Therapeutics Inc.
• Fate Therapeutics Inc.
• Atara Biotherapeutics Inc.
• Intellia Therapeutics Inc.
• Precision Biosciences Inc.
• Takara Bio Inc.
• Tessa Therapeutics
• Adaptimmune Therapeutics plc
• Cellectis S.A.
• Zelluna Immunotherapy AS
• Cellular Biomedicine Group Inc.
• Lion TCR Pte Ltd.
• TCRCure Biopharma Corp.
• Asher Biotherapeutics Inc.
• Be Biopharma Inc.
• Alaunos Therapeutics Inc.
• China Immunotech Inc.

What Are The Regional Insights Into The TCR Therapy Market?

North America was the largest region in the TCR therapy market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the TCR therapy market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.