In-vitro diagnostics (IVD) are used to detect diseases, infections, and conditions and also monitor a person’s state of health and therapeutic procedures by examining specimens derived from the human body such as tissue, blood, stools, urine and the other body fluids. Significant technologies incorporated in in-vitro diagnostics are polymerase chain reaction, microarray techniques, sequencing technology and mass spectrometry, which are used for test sample preparation. In-vitro diagnostic medical devices include reagents, reagent products, control materials, calibration materials, kits, instruments, apparatus, systems, equipment, pregnancy tests, urine test strips, blood sugar monitoring systems for diabetics and receptacles for medical specimens.
The top five companies covered are Siemens Healthineers, F. Hoffmann-La Roche Ltd, Danaher (Beckman Coulter Inc), Abbott Laboratories Inc. and Thermo Fisher Scientific, Inc. Siemens Healthineers was the largest company in the in-vitro diagnostics market in 2017.
The countries covered are USA, China, Germany, Brazil, Japan, UK, Spain, Russia, France, Australia, Italy, India and rest of the world.
The global in-vitro diagnostics market was valued at around $56 billion in 2017. Asia Pacific was the largest region in the in-vitro diagnostics market in 2017, accounting for above 32% market share. The USA was the largest country in the market in 2017, accounting for under 21% market share.
Companies in this market are very active with multiple strategic collaborations and agreements. Top companies in the in-vitro diagnostic market are strategically partnering and collaborating with other companies to broaden their products, technologies and services.
In-vitro diagnostics market is segmented into Point-of-Care Diagnostic, Immunochemistry Diagnostics, Clinical Chemistry Diagnostic, Molecular Diagnostics, Hematology Diagnostic Instruments, Microbiology Diagnostic, Hematology Diagnostic Instruments and Hemostasis Diagnostics.
Point-of-Care Diagnostics devices are designed to aid patients in performing medical diagnostic testing at or near the point of care, for immediate knowledge on diseases or conditions. Point-of-care diagnostics are classified into glucose and cardiometabolic monitoring kits, infectious diseases testing kits, cardiac and cancer markers.
Immunochemistry Diagnostics devices are designed to diagnose diseases or conditions by studying the functions of the immune system through analyzing the nature of specific proteins, antigens, antibodies and their interaction. Based on technology, these devices are divided into enzyme-linked immunosorbent assay, fluorescence immunoassay, chemiluminescence immunoassay, colorimetric immunoassay, rapid tests, radioimmunoassays, western blot and ELISPOT.
Clinical Chemistry Diagnostics are used to analyze body fluids for diagnostic purposes. Based on technologies, these instruments are divided into basic metabolic panel, liver panel, electrolyte panel, renal profile, lipid profile, thyroid function panel and specialty chemical tests. Clinical chemistry devices include albumin analyzers, immunoassay analyzer, osmometers, bilirubinometers, clinical chemistry analyzers, coagulation analyzers, creatinine analyzers, reagents and other products.
Molecular Diagnostics are used to diagnose infectious diseases and perform screening by detecting specific sequences in DNA or RNA. It helps the doctors to prescribe more accurate therapeutic interventions in the early stages of a disease. Molecular diagnostics are divided, based on technology into the polymerase chain reaction, microarrays, isothermal nucleic acid amplification technology, hybridization, DNA sequencing and other technologies.
Hematology Diagnostic Instruments are used to diagnose diseases related to blood, vascular systems, bone marrow, auto immune disorders and hemostasis. These devices include automated cell counter, red cell indices device, micro sedimentation centrifuge, blood volume measuring device, occult blood test, platelet aggregometer, erythrocyte sedimentation rate test, red blood cell enzyme assay kit, glutathione reductase assay and hematology reagents.
Microbiology Diagnostic Devices are used to diagnose infectious diseases by examining pathogens. These instruments include incubators, autoclave sterilizers, anaerobic culture systems, blood culture systems, gram strainers, microscopes, mass spectrometers, molecular diagnostic instruments, reagents pathogen specific kits and general reagents.
Hemostasis Diagnostics are the devices used to determine the hemostatic defects, which cause excessive bleeding. Hemostasis is defined as the stopping or slowing the blood flow from the damaged blood vessel. During the hemostasis, blood changes from liquid state to the gelatinous state. Hemostasis maintained in the body by three mechanisms namely, blood coagulation, platelet plug formation, and vasoconstriction.