The acute kidney injury market has seen considerable growth due to a variety of factors.
• The market size for acute kidney injury has experienced robust growth recently. The market size is projected to increase from $5.37 billion in 2024 to $5.74 billion in 2025, implying a compound annual growth rate (CAGR) of 6.9%.
The expansion during the historical timeframe is primarily due to a surge in chronic illnesses, an aging population, a rise in hospital-acquired infections, amplified awareness about kidney health, and advances in critical care medicine.
The acute kidney injury market is expected to maintain its strong growth trajectory in upcoming years.
• Substantial expansion is projected for the acute kidney injury market in the upcoming years, with predictions estimating it to reach $7.39 billion by 2029, exhibiting a compound annual growth rate (CAGR) of 6.5%.
The escalation anticipated during the forecast period can be associated to the increasing instances of sepsis, surging requirement for individualized treatments, amplified governmental initiatives in healthcare, burgeoning healthcare spending in nascent markets, and an intensified focus on personalized medicine and regenerative treatments. Key trends emerging during the forecast period encompass the introduction of wearable dialysis devices, the utilization of artificial intelligence for refining treatment strategies, portability in renal replacement therapy systems, advancements in continuous renal replacement therapy (CRRT), remote supervision, and the incorporation of telemedicine.
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The escalating incidence of diabetes is anticipated to spur the expansion of the acute kidney injury market. Diabetes encompasses a range of metabolic disorders signified by elevated blood sugar levels due to either insufficient insulin production by the body or cells' inappropriate response to insulin. The surge in diabetes cases is attributed to an assortment of factors, including mounting obesity levels, unhealthy dietary habits, inactive lifestyles, aging demographics, and increased awareness and diagnosis. Acute kidney injury induces metabolic and inflammatory modifications that could affect insulin resistance and glucose balance, underscoring a complex interaction which could influence the evolution and control of diabetes. As an example, data from the UK's Office for Health Improvement & Disparities in March 2024 showed that between March 2022 and March 2023, there was a 22% increase in the proportion of individuals with type 1 diabetes who received all eight recommended care processes. For those with type 2 diabetes, the increase was 21%, and the percentage achieving target HbA1c levels reached 37.9%, the most substantial mark ever recorded by the National Diabetes Audit (NDA). Consequently, the amplified prevalence of diabetes is fueling the expansion of the acute kidney injury market.
The acute kidney injury market covered in this report is segmented –
1) By Injury: Pre-Renal Kidney Injury, Post-Renal Kidney Injury, Intrinsic Kidney Injury
2) By Treatment Type: Dialysis, Drug Therapy, Urinary Implants
3) By End User: Hospitals, Ambulatory Surgical Centers, Other End Users
Subsegments:
1) By Pre-Renal Kidney Injury: Hypovolemia, Heart Failure-Related Injury, Sepsis-Induced Injury, Renal Artery Stenosis, Hepatorenal Syndrome
2) By Post-Renal Kidney Injury: Ureteral Obstruction, Bladder Outlet Obstruction, Prostate Enlargement (Benign Prostatic Hyperplasia), Kidney Stones, Tumors Affecting Urinary Tract
3) By Intrinsic Kidney Injury: Acute Tubular Necrosis (ATN), Acute Interstitial Nephritis (AIN), Glomerulonephritis, Vasculitis, Rhabdomyolysis-Induced Injury
Prominent businesses in the acute kidney injury (AKI) industry are concentrating their efforts on securing regulatory permissions to expand their product range and introduce new treatment alternatives. These permissions come from regulatory bodies like the FDA or EMA, and they signify that a product meets safety, effectiveness, and quality requirements to be marketed and sold. For example, in December 2023, Mission Therapeutics Ltd., a biotech firm based in the UK, was given FDA approval to proceed with a Phase II clinical study for their leading product, MTX652. This product, aimed at patients at high risk of AKI after heart surgery, targets vital routes involved in kidney damage and repairs with the intent to reduce inflammation, prevent additional kidney harm, and stimulate recovery. This trial stands out because it intends to utilize new therapeutic strategies to confront the root molecular factors of AKI, offering potentially more potent treatment choices than current interventions. The security, effectiveness, and pharmacokinetics of MTX652 will be tested in the Phase II trial, which will provide important information that could support more widespread clinical implementation and potential approval.
Major companies operating in the acute kidney injury market are:
• Pfizer Inc.
• F. Hoffmann-La Roche Ltd
• Merck & Co. Inc.
• Sanofi S.A.
• Bristol-Myers Squibb Company
• Novartis AG
• Eli Lilly and Company
• Gilead Sciences Inc.
• Amgen Inc.
• Fresenius Medical Care AG & Co. KGaA
• Asahi Kasei Medical Co. Ltd.
• Teva Pharmaceutical Industries Ltd.
• Baxter International Inc.
• B. Braun Melsungen AG
• Nipro Corporation
• Nikkiso Co. Ltd.
• Quark Pharmaceuticals Inc.
• Kringle Pharma Inc.
• Aptabio Therapeutics Inc.
• Alexion Pharmaceuticals Inc.
• Alloksys Life Sciences B.V.
• AM-Pharma B.V.
• Arch Biopartners Inc.
• Guard Therapeutics International AB
North America was the largest region in the acute kidney injury market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the acute kidney injury market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.