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Global Antidepressants Top Major Players 2025, Forecast To 2034

12 Mar, 2025

What are the Historical Developments and Current Growth Metrics of the Antidepressants Market?

The antidepressants market has seen considerable growth due to a variety of factors.
• In recent times, there has been progressive growth in the size of the antidepressants market. It is projected that by 2025, the market will increase from its estimated value of $17.11 billion in 2024 to approximately $17.82 billion, a compound annual growth rate (CAGR) of 4.2%.
Multiple factors can account for this historic growth, such as the rising prevalence of mental health disorders, the diminishing stigma associated with mental health, improvement in diagnostic practices, diversification in treatment alternatives, government interventions, and the implementation of mental health policies.

How Will The Antidepressants Market Size Evolve In The Foreseeable Future?

The antidepressants market is expected to maintain its strong growth trajectory in upcoming years.
• The market size for antidepressants is projected to witness consistent expansion in the coming years, reaching a value of $20.25 billion by 2029, featuring a compound annual growth rate (CAGR) of 3.2%.
Reasons for the predicted growth in the specified period correspond with the ascension of awareness and advocacy for mental health, worldwide effects of stress and lifestyle modifications, coordination of mental health aid, advancements in psychiatric research, as well as telemedicine and remote mental health aid. Key trends during this forecasted period encompass changes in regulations, competitive market dynamics, growth of the generic market, emphasis on side-effect profiles, and the rise of emerging markets.

What Are the Critical Driver Fuelling the Antidepressants Market's Growth?

Around the globe, the increased prevalence of mental illnesses plays a crucial role in the expansion of the antidepressant drug market, as a large proportion of consumers depend on these drugs to combat conditions such as depression, anxiety, and other mental health related disorders. The use of antidepressants is highlighted in situations involving depression, Obsessive Compulsive Disorder (OCD), childhood bedwetting, major depressive disorder, acute anxiety disorder, bipolar disorder, Post-Traumatic Stress Disorder (PTSD) and social anxiety disorder. Worldwide, the proportion of people suffering from depression ranges between 2% and 6%, with older individuals being more susceptible to depression than any other age groups. The World Health Organization predicts that by 2023, approximately 280 million people worldwide will be battling depression. Consequently, this upsurge in mental health conditions is projected to stimulate the growth of the antidepressant market.

What Are The Core Segments Of The Globa Antidepressants Market?

The antidepressants market covered in this report is segmented –
1) By Product: Selective Serotonin Reuptake Inhibitor (SSRI), Serotonin-norepinephrine Reuptake Inhibitor (SNRI), Tricyclic Antidepressant (TCA), Monoamine Oxidase Inhibitor (MAOI)
2) By Drug Class: Monoamine Oxidase Inhibitors, Serotonin Antagonist And Reuptake Inhibitors, Serotonin-Norepinephrine Reuptake Inhibitors, Selective Serotonin Reuptake Inhibitors, Tricyclic Antidepressants
3) By Depressive Disorder: Major Depressive Disorder, Obsessive-Compulsive Disorder, Generalized Anxiety Disorder, Panic Disorder Subsegments:
1) By Selective Serotonin Reuptake Inhibitor (SSRI): Fluoxetine, Sertraline, Escitalopram, Paroxetine, Citalopram
2) By Serotonin-norepinephrine Reuptake Inhibitor (SNRI): Venlafaxine, Duloxetine, Desvenlafaxine
3) By Tricyclic Antidepressant (TCA): Amitriptyline, Nortriptyline, Imipramine, Doxepin
4) By Monoamine Oxidase Inhibitor (MAOI): Phenelzine, Tranylcypromine, Isocarboxazid

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Which Emerging Trends Are Reshaping The Antidepressants Market Size?

The management of severe depression is a significant trend in the antidepressant industry, where Ketamine stands out as the innovative treatment option. Originally used for anesthesia in surgeries, it boosts glutamate production and encourages the brain to form new neural connections. Consequently, this allows the brain to be more adaptable, fostering the development of new pathways and enabling the patients to cultivate more positive thoughts and actions. For example, the Food and Drug Administration (FDA) endorsed a fresh ketamine depression medication, esketamine, which constitutes one-half of the ketamine compound. The medication necessitates administration through a nasal spray and the patients are required to be on another antidepressant simultaneously. Moreover, only those patients can be prescribed these drugs, who have previously attempted two antidepressants without success.

Who Are the Key Players in the Antidepressants Market?

Major companies operating in the antidepressants market include:
• Pfizer Inc.
• Johnson & Johnson Services Inc.
• F. Hoffmann-La Roche Ltd.
• Merck & Co. Inc.
• AbbVie Inc.
• Novartis AG
• Sanofi S.A.
• Bristol Myers Squibb Company
• Fresenius Kabi AG
• Abbott Laboratories
• AstraZeneca plc
• GlaxoSmithKline plc
• Takeda Pharmaceutical Co. Ltd.
• Eli Lilly and Company
• Boehringer Ingelheim GmbH
• H. Lundbeck AS
• Teva Pharmaceutical Industries Ltd.
• Akeda Pharmaceutical Co.
• Otsuka Pharmaceutical Co.
• Mylan N.V
• Sun Pharmaceuticals Pvt. Ltd.
• Servier Laboratories
• Sumitomo Dainippon Pharma Co.
• Aurobindo Pharma Limited
• Dr. Reddy's Laboratories Ltd.
• Hikma Pharmaceuticals plc
• Allergan plc
• Alkermes plc
• Egis Pharmaceuticals plc
• Forest Laboratories Inc.

What are the Regional Insights into the Antidepressants Market?

North America was the largest region in the antidepressants market in 2024. Middle East is expected to be the largest growing region in the global antidepressants market during the forecast period. The regions covered in the antidepressants market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.