The arthralgia market has seen considerable growth due to a variety of factors.
• The market for arthralgia has seen robust growth in the past few years. It is projected to expand from $5.20 billion in 2024 to $5.64 billion in 2025, reflecting a compound annual growth rate (CAGR) of 8.5%.
The growth during the historic period is due to a rise in the occurrence of autoimmune diseases, an increase in the number of related risk factors, a surge in obesity rates, a higher prevalence of arthralgia, and a rise in the incidence of joint disorders.
The arthralgia market is expected to maintain its strong growth trajectory in upcoming years.
• The market for arthralgia is projected to expand significantly in the coming years, reaching an anticipated valuation of $7.73 billion in 2029, with an 8.2% compound annual growth rate (CAGR). This surge in growth during the forecast period is attributed to factors such as increased knowledge of arthralgia, an aging population, improved healthcare facilities, a growing preference for less invasive treatments, and an uptick in the occurrence of sports-related injuries. Key trends for the forecast period encompass the incorporation of digital health strategies, groundbreaking therapies, cellular treatments, breakthroughs in medical technology, and more significant investment in research and development.
The expected enlargement of the arthralgia market is due to the surge in rheumatoid arthritis incidents. This chronic autoimmune condition primarily targets joints, resulting in inflammation, discomfort, and potential joint impairment. The escalation in rheumatoid arthritis instances is connected to the aging population, genetic predisposition, environmental factors such as smoking and pollution, and shifts in lifestyle. Rheumatoid arthritis causes arthralgia by instigating chronic inflammation in the joints, resulting in pain, stiffness, and progressive damage. For example, Arthritis Australia, a non-profit organization based in Australia, indicated in February 2024 that by 2040, there will be an increase in arthritis, with numbers expected to rise from 4.11 million in 2025 to 5.39 million, osteoarthritis expected to increase from 2.35 million to 3.11 million, and rheumatoid arthritis expected to hit 748,721. Thus, the growth of the arthralgia market is fueled by the escalating numbers of rheumatoid arthritis cases.
The arthralgia market covered in this report is segmented –
1) By Cause: Osteoarthritis, Rheumatoid Arthritis, Gout, Psoriatic Arthritis, Lupus, Injuries, Infections, Other Causes
2) By Treatment Type: Medications, Therapies, Surgical Interventions, Lifestyle And Home Remedies
3) By Route Of Administration: Oral, Injectable, Topical, Transdermal
4) By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies
5) By End User: Hospital, Clinics, Homecare Settings, Rehabilitation Centers
Subsegments:
1) By Osteoarthritis: Knee Osteoarthritis, Hip Osteoarthritis, Hand Osteoarthritis, Spine Osteoarthritis, Shoulder Osteoarthritis
2) By Rheumatoid Arthritis: Seropositive Rheumatoid Arthritis, Seronegative Rheumatoid Arthritis, Juvenile Rheumatoid Arthritis, Early-Onset Rheumatoid Arthritis
3) By Gout: Primary Gout, Secondary Gout, Gouty Arthritis
4) By Psoriatic Arthritis: Symmetric Psoriatic Arthritis, Asymmetric Psoriatic Arthritis, Psoriatic Spondylitis, Distal Interphalangeal Predominant Psoriatic Arthritis
5) By Lupus: Systemic Lupus Erythematosus (SLE), Discoid Lupus Erythematosus, Drug-induced Lupus, Neonatal Lupus
6) By Injuries: Sports-related Injuries, Trauma and Fractures, Sprains and Strains, Tendon or Ligament Damage
7) By Infections: Septic Arthritis, Viral Arthritis, Bacterial Infections, Fungal Infections
8) By Other Causes: Fibromyalgia, Overuse Injuries, Sarcoidosis, Ankylosing Spondylitis, Crystal-induced Arthritis
The arthralgia market is witnessing a shift as top players concentrate on the creation of novel therapies such as RMAT-designated gene therapy. The goal of this therapy is to enhance patient outcomes by offering enduring pain alleviation and elevated joint functionality. RMAT-designated gene therapy is a valuable treatment given the Regenerative Medicine Advanced Therapy (RMAT) tag by the FDA, with the aim of fast-tracking the creation and evaluation of pioneering gene therapies for serious or potentially fatal conditions. An example can be taken from Pacira BioSciences Inc., a pharmaceutical firm based in the United States, which got Regenerative Medicine Advanced Therapy (RMAT) approval for its product PCRX-201 (enekinragene inzadenovec) by the U.S. Food and Drug Administration (FDA) in March 2024. PCRX-201 is an inventive intra-articular gene therapy that employs a helper-dependent adenovirus (HDAd) to address knee osteoarthritis, designed to originate interleukin-1 receptor antagonists (IL-1Ra). Pacira lauded the approval, marking it as the first RMAT approval by the FDA for a gene therapy aimed at osteoarthritis, and underlined the encouraging initial clinical findings indicating that PCRX-201 could be a game-changer in disease treatment.
Major companies operating in the arthralgia market are:
• Pfizer Inc.
• Johnson & Johnson Services Inc.
• AbbVie Inc.
• Sanofi S.A.
• Bristol-Myers Squibb Company
• AstraZeneca PLC
• Novartis AG
• GlaxoSmithKline PLC
• Eli Lilly and Company
• Amgen Inc.
• Teva Pharmaceutical Industries Ltd.
• Regeneron Pharmaceuticals Inc.
• Astellas Pharma Inc.
• Biogen Inc.
• UCB S.A.
• Hikma Pharmaceuticals PLC
• Ferring Pharmaceuticals
• KD Pharma Group S.A.
• SI-BONE Inc.
• Xalud Therapeutics Inc.. Incannex Healthcare Limited
• Cytonics Corporation
• Vitazan Herbs and Vitamins Inc.
North America was the largest region in the arthralgia market in 2024. The regions covered in the arthralgia market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.