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Global B-Cell Maturation Antigen (BCMA) Targeted Therapies Share Report 2025, Forecast To 2034

12 Mar, 2025

What Factors Propelled The Growth Of The B-Cell Maturation Antigen (BCMA) Targeted Therapies Market In The Past?

The b-cell maturation antigen (bcma) targeted therapies market has seen considerable growth due to a variety of factors.
• The market for therapies that focus on the B-cell maturation antigen (BCMA) has seen a significant upsurge in the past few years. The market value is projected to rise from $12.17 billion in 2024 to $15.21 billion in 2025, with a compound annual growth rate (CAGR) of 25.0%.
This marked rise during the historic period can be linked to various factors such as increased attention to hematologic malignancies, substantial investments in oncology research, heightened demand for personalized medicine, wider acceptance of CAR-T cell therapies, and escalating healthcare costs.

What Is The Projected Growth And Market Size For The B-Cell Maturation Antigen (BCMA) Targeted Therapies

The b-cell maturation antigen (bcma) targeted therapies market is expected to maintain its strong growth trajectory in upcoming years.
• We can expect a significant surge in the market size of B-cell maturation antigen (BCMA) targeted therapies in the coming years. It is projected to reach $36.66 billion in 2029, with a compound annual growth rate (CAGR) of 24.6%.
Factors contributing to this growth during the forecast period include an increasing emphasis on cancer research, shifts in target towards specific molecular markers, rising cancer occurrences, a boost in biotech investments, and a growing propensity towards cell and gene therapies. Key future trends include breakthroughs in CRISPR technology, progress in gene-editing techniques, advancements in the next-generation car-t cell therapies, developments in targeted antibody-drug conjugates, and the creation of ready-to-use treatments.

What Key Factors and Trends are Driving the Growth of the B-Cell Maturation Antigen (BCMA) Targeted Therapies Market?

The escalating occurrence of multiple myeloma is slated to stimulate the development of the b-cell maturation antigen (BCMA) targeted therapies market in the upcoming years. Multiple myeloma, a cancer variant primarily impacting plasma cells, key contributors to the immune system for generating antibodies, has seen a rising trend. This increase is brought on by various factors like aging global populace, enhanced diagnostic methodologies, and differences in healthcare availability. BCMA targeted therapies play a pivotal role in dealing with multiple myeloma by targeting and wiping out cancerous plasma cells that express BCMA, thereby presenting a beneficial route for efficient and focused treatment. For example, data from the American Cancer Society, a professional organization based in the US, revealed that in August 2024, about 35,780 fresh cases of multiple myeloma were detected in America, with 19,520 cases in men and 16,260 in women. Furthermore, an estimate of roughly 12,540 fatalities, including 7,020 men and 5,520 women, is expected. Consequently, the escalating occurrence of multiple myeloma is accelerating the growth of the b-cell maturation antigen (BCMA) targeted therapies market.

What Are The Main Segments Of The Global B-Cell Maturation Antigen (BCMA) Targeted Therapies Market?

The B-cell maturation antigen (BCMA) targeted therapies market covered in this report is segmented –
1) By Product Type: Antibody Drug Conjugates, Chimeric Antigen Receptor T (CAR-T)-Cell Therapy, Bispecific Antibodies
2) By Indication Type: Acute Lymphoblastic Leukemia, Multiple Myeloma
3) By End User: Hospitals, Specialty Clinics, Home Care Settings Subsegments:
1) By Antibody Drug Conjugates: BCMA-Targeted ADCs (Antibody-Drug Conjugates), Linker-Payload Technology-Based BCMA ADCs
2) By Chimeric Antigen Receptor T (CAR-T)-Cell Therapy: BCMA CAR-T Cells (Autologous), Allogeneic BCMA CAR-T Cells
3) By Bispecific Antibodies: BCMA x CD3 Bispecific Antibodies, BCMA x CD28 Bispecific Antibodies

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What Emerging Trends Are Influencing The Growth Of The B-Cell Maturation Antigen (BCMA) Targeted Therapies Market?

Leading organizations in the market for B-cell maturation antigen (BCMA) targeted therapies are concentrating on creating innovative treatments such as CAR-T cell therapy to boost the effectiveness and accuracy of cancer cell targeting. CAR-T cell therapy is an immunotherapy approach that alters a patient's T cells to carry chimeric antigen receptors (CARs) capable of targeting and eradicating cancer cells. For example, in April 2024, U.S. pharmaceutical company Johnson & Johnson obtained approval from the U.S. Food and Drug Administration (FDA) for CARVYKTI. CARVYKTI (ciltacabtagene autoleucel) is a BCMA-targeted autologous T-cell immunotherapy that has been genetically modified. It is used for the treatment of adult patients with relapsed or refractory multiple myeloma who have undergone at least one previous line of therapy and are resistant to lenalidomide.

Who Are the Key Players in the B-Cell Maturation Antigen (BCMA) Targeted Therapies Market?

Major companies operating in the B-cell maturation antigen (BCMA) targeted therapies market are include:
• Bristol Myers Squibb Company
• Novartis
• GlaxoSmithKline (GSK)
• Takeda Pharmaceutical Company Limited
• Amgen Inc
• Regeneron Pharmaceuticals
• Beigene
• Arcellx Inc
• Poseida Therapeutics
• Legend Biotech Corporation
• Cartesian Therapeutics
• Juno Therapeutics
• Sutro Biopharma Inc
• CARsgen Therapeutics
• Precision BioSciences
• Eureka Therapeutics Inc
• Cellectis
• Teneobio Inc.
• Janssen Pharmaceuticals Companies
• Allogene Therapeutics
• Affimed
• Bluebird Bio Inc.

What Is The Most Dominant Region In The B-Cell Maturation Antigen (BCMA) Targeted Therapies Market?

North America was the largest region in the B-cell maturation antigen (BCMA) targeted therapies market in 2024. The regions covered in the B-cell maturation antigen (BCMA) targeted therapies market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.