The cloning and mutagenesis market has seen considerable growth due to a variety of factors.
•In recent times, the cloning and mutagenesis market size has experienced rapid expansion. Projected growth indicates an increase from $2.98 billion in 2024 to $3.56 billion in 2025, at a compound annual growth rate (CAGR) of 19.5%.
This significant growth during the historical period can be linked to progress in genetic research, an upturned demand in pharmaceutical studies, the emergence of genetic engineering in agricultural fields, applications in biomedical research and innovative uses in molecular biology.
The cloning and mutagenesis market is expected to maintain its strong growth trajectory in upcoming years.
• Expect a notable increase in the size of the cloning and mutagenesis market over the forthcoming years, with it forecasted to reach "$7.2 billion by 2029. This will be a result of a compound annual growth rate (CAGR) of 19.3%.
Factors influencing this market growth within the forecast period include growing usage in gene therapy, an increase in demand for personalized medicine, developments in functional genomics, progress in synthetic biology, and application in agricultural biotechnology. Interesting trends to follow in this period will be targeted gene therapy, enhanced specificity and accuracy, customizable molecular tools, widespread use in agriculture, and ethical and regulatory considerations.
The cloning and mutagenesis market is projected to expand rapidly due to the increasing demand for genetically engineered products. These products include any organism or substance that has been altered through genetic engineering to exhibit new traits. Cloning creates identical genetic copies of various organisms, making them resistant to insects and diseases, and is also used in gene therapy within the medical science field. This amplifying interest in genetically modified products is aiding the cloning and mutagenesis market's growth. For example, Bayar AG, a biotechnology and pharmaceutical firm based in Germany, reported in their annual account for February 2023 that their crop sciences and pharmaceutical sector, which includes genetically modified items, saw a substantial rise in yearly sales over 2021. These sales rose from $22,314.79 million in 2021 to $27,794.38 million in 2022. Hence, the growing demand for genetically engineered products is fueling the cloning and mutagenesis market's expansion.
The cloning and mutagenesis market covered in this report is segmented –
1) By Product: Cloning Kits, Mutagenesis Kits, Other Product
2) By Technique: Blunt End Cloning, Topo PCR Cloning, Seamless Cloning, Site-Directed Mutagenesis, Other Techniques
3) By End User: Academic and Research Institutes, Biotechnology Companies, Other End User
Subsegments:
1) By Cloning Kits: Bacterial Cloning Kits, Yeast Cloning Kits, Viral Cloning Kits, Plasmid Cloning Kits
2) By Mutagenesis Kits: Site-Directed Mutagenesis Kits, Random Mutagenesis Kits, Error-Prone PCR Kits, CRISPR Or Cas9 Mutagenesis Kits
3) By Other Products: Enzymes, Vector Systems, Accessories
Main players in the cloning and mutagenesis industry are stepping ahead by advancing technologies like bacteriophage genome modification to grab a higher market share. The said technology involves specific techniques and instruments for altering bacteriophage's genetic matter—viruses that attack bacteria—for several industrial, therapeutic, or research purposes. In October 2022, for instance, a biotech firm based in South Korea, iNtRON Biotechnology, unveiled its second-gen technology for Robot Bacteriophage. This entails the usage of random transposon mutagenesis for altering the bacteriophage genome. This innovatory move, along with the formerly designed customised CRISPR/Cas system, aids in pinpointing and removing non-essential genes in the bacteriophage's genome. The firm's goal is to design and develop bacteriophages with particular attributes freely, thereby contributing to creating immunotherapeutic drugs and antiviral remedies.
Major companies operating in the cloning and mutagenesis market include:
• Thermo Fisher Scientific
• Takara Bio Inc.
• Agilent Technologies Inc.
• Jena Bioscience GmbH
• Transgen Biotech Co
• New England Biolabs
• Merck KGaA
• Promega Corporation
• Bio-Rad Laboratories Inc.
• Danaher
• Genomax Technologies Pte Ltd
• GENEWIZ Inc.
• abm Inc.
• GenScript
• EZBioscience
• Codex DNA Inc.
• Aragen Life Sciences
• Bio-Techne
• Charles River Laboratories
• Integrated DNA Technologies
• MedGenome
• Sino Biological Inc.
• BioChain Institute Inc.
• OriGene Technologies Inc.
• Creative Biogene
• Bioneer Corporation
• Synbio Technologies LLC
• Lucigen Corporation
• Biomatik Corporation
• Quanta BioDesign Ltd.
• Inscripta Inc.
North America was the largest region in the cloning and mutagenesis market in 2024.Asia-pacific is expected to be the fastest-growing region in the global cloning and mutagenesis market report during the forecast period. The regions covered in the cloning and mutagenesis market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa