The Controlled Substance Market Overview 2025 report reveals that the market size has grown significantly over the past few years, with projections indicating further expansion.
The market size of the controlled substance industry has seen substantial growth recently, increasing from $94.86 billion in 2024 to $101.15 billion in 2025. This growth represents a compound annual growth rate (CAGR) of 6.6%.
The Controlled Substance market is projected to reach a size of $136.51 billion by 2029, growing at a compound annual growth rate (CAGR) of 7.8%.
Download Your Free Sample of the 2025 Controlled Substance Market Report and Uncover Key Trends Now!The key drivers in the controlled substance market are:
• The advent of precision medicine, telemedicine and remote healthcare
• Development of alternatives to opioids
• Ongoing updates in regulatory policies
• Enhanced focus on mental health care.
The controlled substance market covered in this report is segmented –
1) By Drug: Opioids, Stimulant, Depressants, Cannabinoids
2) By Distribution Channel: Hospital Pharmacy, Retail Pharmacy, Online Pharmacy
3) By Application: Pain Management, Sleep Disorders, Depression And Anxiety, Seizure, Attention Deficit Hyperactivity Disorder (ADHD), Other Applications
The key trends in the controlled substance market are:
• The future of the controlled substance market is being shaped by regulatory changes and compliance.
• Emphasis on drug safety and abuse prevention is a growing trend in the market.
• Advancements in drug delivery technologies are significantly influencing future trends.
• The emergence of biosimilars and generic versions, along with the integration of digital health solutions, are key future trends.
Major companies in the controlled substance market are:
• Merck & Co. Inc.
• Johnson and Johnson Services Inc.
• Orbis Biosciences Inc.
• GW Pharmaceuticals plc
• Corium Inc.
• Aradigm Corporation
• Alkermes plc
• Sun Pharmaceutical Ltd.
• F. Hoffmann-La Roche Ltd.
• AbbVie Inc.
• Ampac Fine Chemicals
• Siegfried Holding AG
• Pfizer Inc.
• Novartis AG
• GlaxoSmithKline plc
• Sanofi S.A.
• Bristol-Myers Squibb
• Eli Lilly and Company
• AstraZeneca
• Teva Pharmaceutical Industries
• Viatris Inc.
• Boehringer Ingelheim
• Gilead Sciences
• Amgen
• Regeneron Pharmaceuticals
• Abbott Laboratories
• Mallinckrodt Pharmaceuticals
• Endo International
• Catalent
• Cambrex Corporation
• Lonza Group
• Indivior plc
• Ipsen SA
North America was the largest region in the controlled substance market in 2024