The kanuma market has seen considerable growth due to a variety of factors.
• The scale of the Kanuma market, which has witnessed a steady XX (HCAGR) in recent years, is predicted to expand from a value of $XX million in 2024 to $XX million in 2025, delivering a compound annual growth rate (CAGR) of XX%.
The augmentation during the historic period owes much to the factors such as growing recognition of unusual genetic afflictions, surging incidence of pediatric LAL-D cases, endorsements for enzyme replacement remedies like Kanuma, enhancement of healthcare framework in budding markets, and the broadening of insurance provisions for treatments of rare diseases.
The kanuma market is expected to maintain its strong growth trajectory in upcoming years.
• In the coming years, the size of the kanuma market is projected to experience an XX (FCAGR) increase. The market is anticipated to escalate to $XX million by 2029, growing at a compound annual growth rate (CAGR) of XX%.
The expected growth during the forecast period is due to factors such as the increasing demand for personalized medicine, an intensified focus on the early diagnosis and treatment of rare diseases, higher global incidence of genetic disorders, government backing for the development of orphan drugs, and improved campaigns for patient awareness. Key trends during this forecast period include the enhancement of diagnostic technologies for LAL-D, the advent of innovative treatment delivery mechanisms, progress in biotechnology and enzyme therapy development, collaborations between biotechnology companies and health authorities, and the creation of combination therapies for rare diseases.
The growing occurrence of lysosomal acid lipase deficiency (LAL-D), a rare genetic disorder resulting in lipid accumulation in organs and causing liver dysfunction, cardiovascular problems, and metabolic complications, is projected to propel the kanuma market. The escalation in LAL-D cases is due to advancements in diagnostic techniques and increased awareness, resulting in enhanced detection of this uncommon genetic ailment. Kanuma serves as a treatment for LAL-D by substituting the missing enzyme, thereby decreasing lipid buildup and averting organ injury. For example, a National Institutes of Health report in March 2023, a US-based health research agency, indicated that the total disease prevalence of LAL-D varies from 1:40,000 to 1:300,000, contingent on ethnicity and geographical positioning. Consequently, the rising incidence of LAL-D is stimulating the growth of the kanuma market.
The kanuma market covered in this report is segmented –
1) By Indication: Treatment Of Lysosomal Acid Lipase Deficiency, Treatment Of Associated Conditions
2) By Formulation: Injectable Formulation, Lyophilized Powder For Reconstitution
3) By Patient Demographics: Pediatric Patients, Adult Patients, Geriatric Patients
4) By Distribution Channel: Direct Sales, Wholesalers And Distributors, Retail Pharmacies, Online Pharmacies
5) By End User: Hospitals, Specialty Clinics, Home Healthcare Providers, Research Institutions
One of the main trends in the Kanuma market involves a focus on enzyme replacement therapy (ERT) to secure a competitive advantage in the sector. ERTs like Kanuma serve as substitutes for the insufficient lysosomal acid lipase enzyme, thereby minimizing organ lipid accumulation and the risk of harsh complications linked to LAL-D. An illustration of this happened in November 2023, as per a publication by the National Health Service (NHS), the public healthcare system in the UK. It was announced that sebelipase alfa (Kanuma), an ERT, would be the premier treatment provided by the NHS for Wolman disease, a rare and deadly genetic disorder affecting infants and young children. This progress occurred subsequent to a business deal made by NHS England, coupled with an endorsement from the National Institute for Health and Care Excellence (NICE).
Major companies operating in the kanuma market include:
• AstraZeneca PLC
North America was the largest region in the kanuma market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the kanuma market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.