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Global mRNA Therapeutics Trends 2025, Forecast To 2034

25 Mar, 2025

What Fueled The Previous Growth In The mRNA Therapeutics Market?

The mrna therapeutics market has seen considerable growth due to a variety of factors.
• The mRNA therapeutics market has shown steady growth in recent years. It will expand from $34.76 billion in 2024 to $36.25 billion in 2025 at a CAGR of 4.3%.
This growth is driven by increased financial support for efficient pharmaceutical and vaccine development, expanded federal programs for RNA-based medicines, heightened awareness of rare genetic diseases, and a growing number of clinical trials.

What Can Be Expected from the mRNA Therapeutics Market Size?

The mrna therapeutics market is expected to maintain its strong growth trajectory in upcoming years.
• The mRNA therapeutics market is projected to reach $42.23 billion by 2029, growing at a CAGR of 3.9%.
The growth is driven by the rise in infectious diseases, increased patient visits, expanding applications, demand for personalized medicine, and favorable regulatory environments. Key trends include advancements in mRNA delivery, self-amplifying mRNA platforms, scalability in manufacturing, and novel mRNA modifications.

What Are the Critical Driver Fuelling The mRNA Therapeutics Market's Growth?

The growing prevalence of long-lasting and communicable diseases is expected to drive the growth of the mRNA therapeutics market. These diseases, such as tuberculosis and HIV/AIDS, are increasing due to global travel and weak healthcare infrastructure. mRNA therapeutics are critical in combating these diseases by boosting the body’s immune response. The UK Government reported in October 2023 that the number of people living with diagnosed HIV in England increased by 3% from 2021 to 2022.

How Is The mRNA Therapeutics Market segmented?

The mRNA therapeutics market covered in this report is segmented –
1) By Product: Vaccines, Drugs
2) By Application: Infectious Diseases, Oncology, Rare Genetic Diseases, Respiratory Diseases, Other Applications
3) By End Use: Hospitals And Clinics, Research Organizations, Other End Uses Subsegments:
1) By Vaccines: Infectious Disease Vaccines, Cancer Vaccines, Other Therapeutic Vaccines
2) By Drugs: Oncology Drugs, Cardiovascular Drugs, Autoimmune Disease Drugs, Other mRNA-Based Drugs

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What Emerging Trends Are Influencing The Growth Of The mRNA Therapeutics Market?

Leading companies in the mRNA therapeutics market are focusing on creating innovative solutions like mRNA-based booster vaccines to improve immunity against constantly changing viral strains. An mRNA-based booster vaccine leverages messenger RNA technology to reinforce and extend protection against specific viruses often after the primary vaccine series. For instance, in June 2023, India's Gennova Biopharmaceuticals Ltd. introduced the country's first domestic mRNA-based booster vaccine specifically designed for the Omicron variant of SARS-CoV-2, known as GEMCOVAC-OM. This variant-specific vaccine is designed to trigger appropriate immunity against the Omicron variant. GEMCOVAC-OM is thermostable and doesn't necessitate ultra-cold chain facilities, and it is deliverable without using a needle through a needle-free system, thus simplifying its roll-out in remote parts in India. It was found in clinical trials to significantly boost immune responses compared to other vaccines, underlining the requirement for variant-specific vaccines to produce optimal immunity.

Who Are the Key Players In The mRNA Therapeutics Market?

Major companies operating in the mRNA therapeutics market are:
• Pfizer Inc.
• Novartis AG
• Sanofi AG
• AstraZeneca plc
• GlaxoSmithKline plc
• Hoffmann-La Roche AG
• Moderna Therapeutics Inc
• BioNTech SE
• Vertex Pharmaceuticals Incorporated
• Catalent Inc
• Alnylam Pharmaceuticals Inc
• Sarepta Therapeutics Inc
• Arcturus Therapeutics Holdings Inc
• CureVac N.V
• Ethris GMBH
• eTheRNA immunotherapies NV
• In-Cell-Art S.A.S.
• Nutcracker Therapeutics Inc
• SCM LifeScience Co Ltd
• Suzhou Abogen Biosciences Co Ltd
• Tiba Biotech LLC
• CSPC Pharmaceutical Group
• CRISPR Therapeutics AG

What Is The Most Dominant Region In The mRNA Therapeutics Market?

North America was the largest region in the mRNA therapeutics market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the mRNA therapeutics market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.