The organoids and spheroids market has seen considerable growth due to a variety of factors.
• The organoids and spheroids market has experienced rapid growth. It will grow from $1.16 billion in 2024 to $1.45 billion in 2025, at a compound annual growth rate (CAGR) of 24.6%.
The growth can be attributed to advances in stem cell research, increased investment in 3D cell culture technologies, a rise in chronic diseases, and the growing use of organoids and spheroids in drug testing and regenerative medicine.
The organoids and spheroids market is expected to maintain its strong growth trajectory in upcoming years.
• The organoids and spheroids market is projected to grow to $3.46 billion by 2029, with a CAGR of 24.4%.
This rapid growth is driven by ongoing technological advancements, personalized medicine expansion, cancer research applications, regulatory developments, and growth in commercial products. Major trends include integration with advanced technologies, high-throughput screening for drug discovery, 3D bioprinting, and the use of organoids in cancer modeling.
The growth of the organoids and spheroids market is projected to be driven by the heightened demand for cell therapy and tissue engineering. These processes utilize live cells or crafted tissues to mend, replace, or regenerate damaged organs and tissues within the body. The pressing demand for these methodologies is owed to their promising ability to regenerate impaired tissues and provide treatments for conditions previously deemed incurable, thereby presenting enterprising solutions in the realm of regenerative medicine. Organoids and spheroids play a critical role in these areas by modeling complicated tissues and assessing therapeutic procedures in vitro. For instance, data from Cell & Gene, a US-based digital resource for research academics, shows that as of February 2023, there were 27 FDA-sanctioned cell and gene therapies (CGTs), accounting for roughly 8% of the 340 sanctioned biologics in 2022. This number rose from the 22 approved in 2021. This escalating demand for cell therapy and tissue engineering is expected to stimulate the growth of the organoids and spheroids market.
The organoids and spheroids market covered in this report is segmented –
1) By Type: Organoids, Spheroids
2) By Method: Extracellular Matrix Scaffold Method, Spinning Bioreactor Method, Hanging Drop Method, Low Adherent Culture Plate Method, Magnetic levitation Method, Other Methods
3) By Application: Developmental Biology, Personalized Medicine, Regenerative Medicine, Disease Pathology Studies, Drug Toxicity And Efficacy Testing
4) By End User: Biotechnology And Pharmaceutical Industry, Academic And Research Institutes, Hospitals And Diagnostic Centers
Subsegments:
1) By Organoids: Intestinal Organoids, Liver Organoids, Brain Organoids, Kidney Organoids, Lung Organoids, Pancreatic Organoids, Cardiac Organoids, Retinal Organoids, Tumor Organoids, Organoids For Disease Modeling
2) By Spheroids: Cancer Spheroids, Neural Spheroids, Cardiac Spheroids, Liver Spheroids, Muscle Spheroids, Endothelial Spheroids, Stem Cell-Derived Spheroids, 3D Cell Culture Spheroids
Leading companies in the organoids and spheroids market are focusing their efforts on the creation of advanced tools such as single-particle dispensers to increase precision in cell handling and improve the consistency of research results. Single-particle dispensers are high-precision devices designed to separate and distribute individual cells or particles, ensuring exact control and handling for research and diagnostic uses. For instance, in July 2024, Swiss biotech company SEED Biosciences launched Dispen3D, an innovative instrument tailored for the precise dispensation of individual spheroids and organoids. This marked a noteworthy stride in the manipulation of 3D cell models. The newly introduced dispenser allows researchers to speedily and accurately transport single spheroids into multi-well plates, hence automating the process and guaranteeing monoclonality - a necessary aspect in the discovery of drugs and personal medical care. By operating under low pressures, Dispen3D carefully manages delicate cells while preserving their structure and liveliness. Its easy-to-use design means it can be easily adopted across various research settings, meeting the increasing interest for state-of-the-art tools within the sphere of biological sciences.
Major companies operating in the organoids and spheroids market are:
• Thermo Fisher Scientific Inc.
• Merck KGaA
• Corning Incorporated
• Lonza Group AG
• StemCell Technologies Canada Inc.
• Greiner Bio-One International AG
• Promega Corporation
• Molecular Devices LLC
• American Type Culture Collection (ATCC)
• Mimetas B.V.
• InSphero AG
• HUB Organoids
• Emulate Inc.
• 3D Biomatrix Inc.
• Prellis Biologics Inc.
• 3D Biotek LLC
• DefiniGEN Limited
• Visikol Inc.
• Organovo Holdings Inc.
• Cellesce Ltd.
• AMS Biotechnology (Europe) Limited
North America was the largest region in the organoids and spheroids market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the organoids and spheroids market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.