The protein purification and isolation market has seen considerable growth due to a variety of factors.
• The market for protein purification and isolation has witnessed swift expansion in the recent past. The market size is set to increase from $9.47 billion in 2024 to $10.45 billion in 2025, boasting a compound annual growth rate (CAGR) of 10.4%.
Factors triggering this growth in the historic period include the amplified research and development activities in the field of biopharmaceuticals, expansion of the biotechnology sector, escalating demand for superior quality proteins, growth of academic and research institutes, and advancements in chromatography methods.
The protein purification and isolation market is expected to maintain its strong growth trajectory in upcoming years.
• Forecasts suggest that the protein purification and isolation market is primed for significant expansion in the coming years, with anticipations of reaching $16.31 billion by 2029, delivering a compound annual growth rate (CAGR) of 11.8%.
The expected growth during this forecasted period will be driven by the expanding biologics market, escalated funding for research in life sciences, the rising demand for personalized medicine, growth of contract manufacturing organizations (CMOs), and a surge in demand for quick screen tests. Anticipated trends for the forecasted duration include the use of single-use systems in protein purification, the incorporation of high-throughput purification technologies, a focus on continuous processing, automating protein purification processes, and dedication to sustainable and eco-friendly practices.
The protein purification and isolation market is predicted to thrive due to an uptick in governmental spending on research and development within the pharmaceutical and biotechnology sectors. These research and development efforts contribute to the creation of innovative products or the enhancement of existing ones. A boost in such investments allows for the evolution of superior protein purification procedures and also yields various other advantages, like the purification of hormones' growth factors, DNA polymerases, and reverse transcriptase. For instance, in March 2023, as per the White House- the President of the United States' official residence and workplace, over $3.4 billion was set aside for Cancer Moonshot-oriented R&D. This funding supports a broad range of research initiatives in laboratory-based, clinical, public health, and environmental health across several departments and agencies. Out of this amount, $2.9 billion is allocated exclusively to the Department of Health and Human Services to intensify Cancer Moonshot initiatives at National Cancer Institute and ARPA-H. In addition, over $135 million was designated for veteran mental health and suicide prevention at the Department of Veterans Affairs' medical care. Hence, this augmented governmental spending on pharmaceutical and biotechnology research and development is fuelling the protein purification and isolation market's expansion.
The protein purification and isolation market covered in this report is segmented –
1) By Product: Instruments, Consumables
2) By Technology: Ultrafiltration, Precipitation, Preparative Chromatography, Electrophoresis, Western Blotting, Dialysis And Diafiltration, Centrifugation
3) By Application: Drug Screening, Protein-Protein Interaction Studies, Biomarker Discovery, Target Identification, Protein Therapeutics, Disease Diagnostics And Monitoring
4) By End User: Academic Medical Institutes, Hospitals And Diagnostic Centers, Pharmaceutical And Biotechnology Companies, Contract Research Organizations
Subsegments:
1) By Instruments: Chromatography Systems, Centrifuges, Electrophoresis Systems, Filtration Systems, Other Instruments
2) By Consumables: Resins And Media, Columns, Kits And Reagents, Membranes, Other Consumables
Leading firms in the protein purification and isolation sector are focusing on product innovation, like Amspher A+, to amplify the efficiency and success of protein separation procedures, while simultaneously increasing yield and purity for biopharmaceutical applications. To exemplify, in September 2024, JSR Life Sciences, LLC., a US-based biotech company, introduced Amsphere A+. The Amsphere A+ combines advanced polymer technology with a unique protein ligand, outperforming its predecessor, Amsphere A3, in terms of binding capacity, alkali stability, and pressure-flow attributes. These improvements result in superior efficiency in the production process. Overall, Amsphere A+ signifies a key improvement in performance.
Major companies operating in the protein purification and isolation market include:
• Abcam PLC
• Agilent Technologies Inc
• Thermo Fisher Scientific Inc.
• Bio-Rad Laboratories Inc.
• BioVision Inc.
• Norgen Biotek Corp.
• GE Healthcare Technologies Inc.
• GEA Group AG
• Expedeon Ltd.
• Creative Biostructure
• Qiagen NV
• Geno Technology Inc.
• The Merck Group
• Labome
• Promega Corporation
• OPRL Biosciences Pvt. Ltd.
• Purolite LLC
• Takara Bio Inc.
• F. Hoffmann-La Roche Ltd
• Sigma-Aldrich Chemicals Private Limited
• Cygnus Technologies LLC
• Novasep
• Kinnakeet Biotechnology LLC
• Cambryn Biologics LLC
• Worthington Biochemical Corporation
• GenScript Biotech Corporation
• Creative BioMart
• OriGene Technologies Inc.
• Proteintech Group Inc.
• Rockland Immunochemicals Inc.
• Sino Biological Inc.
North America was the largest region in the protein purification and isolation market in 2024. The regions covered in the protein purification and isolation market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa