Angioedema Treatment Market Report 2026

Angioedema Treatment Market Overview

• Angioedema Treatment market size has reached to $3.13 billion in 2025 • Expected to grow to $6.18 billion in 2030 at a compound annual growth rate (CAGR) of 14.5% • Growth Driver: Rise In Rare Disease Diagnoses Fueling The Growth Of The Market Due To Improving Genetic Testing And Diagnostics • Market Trend: Innovative Long-Term Preventive Therapy For Hereditary Angioedema • North America was the largest region in 2025.

What Is Covered Under Angioedema Treatment Market?

Angioedema treatment refers to the medical management of swelling beneath the skin or mucous membranes, often caused by an allergic reaction, medication side effects, or a genetic condition. This swelling can be triggered by allergic reactions, genetic conditions, medications, or sometimes unknown causes, and the treatment aims to reduce symptoms, prevent airway obstruction, and minimize the frequency and severity of attacks. The main types of angioedema treatment include allergic angioedema, drug-induced angioedema, idiopathic angioedema, and hereditary angioedema. Allergic angioedema refers to swelling caused by an allergic reaction to substances such as foods, insect bites, or medications. It can be administered through injection and orally, catering to diverse end users, including hospitals and clinics, as well as research organizations.

What Is The Angioedema Treatment Market Growth Forecast?

The angioedema treatment market size is expected to see rapid growth in the next few years. It will grow to $6.18 billion in 2030 at a compound annual growth rate (CAGR) of 14.5%. The growth in the forecast period can be attributed to biologic drug development, genetic testing growth, specialty allergy clinics, patient education, preventive care focus. Major trends in the forecast period include increased use of targeted bradykinin therapies, growth of hereditary angioedema treatments, expansion of emergency treatment protocols, improved diagnostic awareness, focus on preventive therapies.

Global Angioedema Treatment Market Segmentation

1) By Type: Allergic Angioedema, Drug-Induced Angioedema, Idiopathic Angioedema, Hereditary Angioedema 2) By Route Of Administration: Injection, Oral 3) By End Use: Hospitals, Clinics, Research Organizations Subsegments: 1) By Allergic Angioedema: Antihistamines, Corticosteroids, Epinephrine, Immunotherapy, Allergen Avoidance Therapies 2) By Drug-Induced Angioedema: Discontinuation of Causative Drug, Antihistamines, Corticosteroids, Epinephrine, Bradykinin Pathway Inhibitors 3) By Idiopathic Angioedema: Empirical Antihistamine Therapy, Corticosteroid Therapy, Leukotriene Receptor Antagonists, Monoclonal Antibodies, Observation and Symptom Management 4) By Hereditary Angioedema: C1 Esterase Inhibitor Replacement Therapy, Bradykinin B2 Receptor Antagonists, Kallikrein Inhibitors, Attenuated Androgens, Antifibrinolytics

What Is The Driver Of The Angioedema Treatment Market?

A rise in the incidence of rare diseases is expected to propel the growth of the angioedema treatment market going forward. Rare diseases refer to medical conditions that affect a very small portion of the population, often with limited treatment options and significant health impacts. The occurrence of rare diseases is increasing due to advancements in genetic testing and diagnostic technologies that enable healthcare professionals to detect and accurately diagnose previously overlooked conditions, leading to a higher reported prevalence. Angioedema treatment is helpful for rare diseases such as hereditary angioedema by providing targeted therapies that help prevent and manage severe swelling episodes, improving patient outcomes. For instance, in November 2024, according to the Food and Drug Administration, a US-based federal agency, more than 7,000 rare diseases impacted over 30 million individuals in the United States. Therefore, the rise in the incidence of rare diseases is driving the growth of the angioedema treatment industry.

Key Players In The Global Angioedema Treatment Market

Major companies operating in the angioedema treatment market are Sanofi SA, Takeda Pharmaceutical Company Limited, Viatris Inc., Otsuka Pharmaceutical Co. Ltd., Fresenius Kabi AG, Bausch Health Companies Inc., Apotex Inc., Aurobindo Pharma Ltd., Dr. Reddy’s Laboratories Ltd, Cipla Inc., Alnylam Pharmaceuticals Inc, Ionis Pharmaceuticals Inc., Salix Pharmaceuticals Ltd, BioCryst Pharmaceuticals Inc., Pharming Group NV, Pharvaris Netherlands B.V, Astria Therapeutics, Intellia Therapeutics, KalVista Pharmaceuticals Ltd., ADARx Pharmaceuticals, Adverum Biotechnologies Inc.

Global Angioedema Treatment Market Trends and Insights

Major companies operating in the angioedema treatment market are focusing on developing innovative solutions, such as subcutaneous injections, to offer more convenient and rapid relief for patients suffering from acute hereditary angioedema (HAE) attacks. Subcutaneous injections are a method of delivering medication into the fatty tissue just beneath the skin for slow and steady absorption into the bloodstream. For instance, in April 2025, CSL Limited, an Australia-based biotechnology company, launched ANDEMBRY (garadacimab) as a novel, fully human monoclonal antibody treatment for preventing acute attacks in patients with hereditary angioedema (HAE). ANDEMBRY is the first pre-filled pen for once-monthly subcutaneous administration, offering a convenient long-term prophylactic option. The drug works by inhibiting activated Factor XII (Factor XIIa), a key initiator in the cascade leading to angioedema. It represents a significant advancement in HAE management by providing effective, patient-centric disease control.

What Are Latest Mergers And Acquisitions In The Angioedema Treatment Market?

In December 2023, Ionis Pharmaceuticals Inc., a US-based biotechnology company, partnered with Otsuka Pharmaceutical Co., Ltd. to commercialize donidalorsen in Europe for the treatment of hereditary angioedema. This partnership aims to accelerate the regulatory approval and commercialization of donidalorsen in Europe, making this innovative therapy available to hereditary angioedema patients through Otsuka’s regional expertise and market presence. Otsuka Pharmaceutical Co., Ltd. is a Japan-based pharmaceutical company that offers treatments for hereditary angioedema (HAE).

Regional Insights

North America was the largest region in the angioedema treatment market in 2025. The regions covered in this market report are Asia-Pacific, South East Asia, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in this market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Taiwan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

What Defines the Angioedema Treatment Market?

The angioedema treatment market consists of revenues earned by entities providing services, such as antihistamine administration, diagnostic services, corticosteroid therapy, genetic counseling, and immunology services. Values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

How is Market Value Defined and Measured?

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified). The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

What Key Data and Analysis Are Included in the Angioedema Treatment Market Report 2026?

The angioedema treatment market research report is one of a series of new reports from The Business Research Company that provides market statistics, including industry global market size, regional shares, competitors with the market share, detailed market segments, market trends and opportunities, and any further data you may need to thrive in the angioedema treatment industry. The market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future state of the industry.