Avascular Necrosis Market Report 2026

Avascular Necrosis Market Overview

• Avascular Necrosis market size has reached to $0.89 billion in 2025 • Expected to grow to $1.38 billion in 2030 at a compound annual growth rate (CAGR) of 9.2% • Growth Driver: Rising Knee And Hip Replacement Surgeries Driving The Market Due To Increasing Risk Of Post-Surgical Bone Complications • North America was the largest region in 2025 and Asia-Pacific is the fastest growing region.

What Is Covered Under Avascular Necrosis Market?

Avascular necrosis (AVN) is a medical condition in which bone tissue dies due to a lack of blood supply. When the blood flow to a bone is interrupted or reduced, the bone cells begin to die, leading to the collapse of the bone structure and eventual joint damage. Avascular necrosis results from trauma, long-term use of steroids, excessive alcohol consumption, or certain medical conditions. The main types of avascular necrosis are trauma-related avascular necrosis and non-trauma-related avascular necrosis. Trauma-related avascular necrosis occurs after a bone injury, such as a fracture or joint dislocation, which blocks blood flow and causes bone tissue to die. It includes various diagnosis methods, such as imaging, biopsy, computed tomography (CT) scan, positron emission tomography (PET), and X-ray, used for various treatment types, including medications, surgery, physical therapy, lifestyle changes, and bone grafting. It includes various end-users, such as hospitals, specialty clinics, rehabilitation centers, ambulatory surgical centers, and home care settings.

What Is The Avascular Necrosis Market Growth Forecast?

The avascular necrosis market size is expected to see strong growth in the next few years. It will grow to $1.38 billion in 2030 at a compound annual growth rate (CAGR) of 9.2%. The growth in the forecast period can be attributed to advanced imaging adoption, regenerative medicine research, aging population, sports injury prevalence, orthopedic innovation. Major trends in the forecast period include rising use of early diagnostic imaging, increased adoption of joint-preserving therapies, growth of minimally invasive surgical procedures, expansion of physical rehabilitation programs, focus on early-stage disease intervention.

Global Avascular Necrosis Market Segmentation

1) By Type: Trauma Related Avascular Necrosis, Non-Trauma Related Avascular Necrosis 2) By Diagnosis: Imaging, Biopsy, Computed Tomography Scan, Positron Emission Tomography, X-Ray 3) By Treatment Type: Medications, Surgery, Physical Therapy, Lifestyle Changes, Bone Grafting 4) By End-User: Hospitals, Specialty Clinics, Rehabilitation Centers, Ambulatory Surgical Centers, Home Care Settings Subsegments: 1) By Trauma-Related Avascular Necrosis: Fracture-Induced Avascular Necrosis, Dislocation-Induced Avascular Necrosis, Post-Surgical Avascular Necrosis, Crush Injury-Related Avascular Necrosis, Sports Injury-Associated Avascular Necrosis 2) By Non-Trauma Related Avascular Necrosis: Steroid-Induced Avascular Necrosis, Alcohol-Induced Avascular Necrosis, Sickle Cell Disease-Associated Avascular Necrosis, Lupus-Related Avascular Necrosis, Radiation Therapy-Induced Avascular Necrosis, Idiopathic Avascular Necrosis

What Are The Drivers Of The Avascular Necrosis Market?

The growing number of knee replacements and hip surgeries is expected to propel the growth of the avascular necrosis market going forward. Knee replacements and hip surgeries refer to surgical procedures used to replace damaged joints and relieve pain in severe cases of avascular necrosis. The number of knee replacements and hip surgeries is increasing due to the growing prevalence of osteoarthritis, which causes severe joint pain and mobility issues, often requiring surgical intervention for relief and improved quality of life. Avascular necrosis significantly contributes to the need for knee replacements and hip surgeries. The condition causes bone tissue to die due to reduced blood supply, often leading to joint deterioration and collapse. For instance, in November 2024, according to the American Joint Replacement Registry (AJRR), a US-based registry run by the American Academy of Orthopaedic Surgeons, in 2023, the number of hip and knee arthroplasty procedures captured in the registry surpassed 4 million, marking an 18% increase compared to 2022. Therefore, the growing number of knee replacements and hip surgeries is driving the growth of the avascular necrosis industry. The rising healthcare expenditure is expected to propel the growth of the avascular necrosis market going forward. Healthcare expenditure is the total amount spent on health services, treatments, and medical products within a population or healthcare system. Healthcare expenditure is rising due to the increasing prevalence of chronic diseases, which require long-term management, frequent hospital visits, and costly medications. Healthcare expenditure is useful for avascular necrosis by enabling access to timely diagnosis, advanced treatments, and surgical procedures that help manage the condition and improve patient outcomes. For instance, in April 2025, according to the American Medical Association, a US-based professional association and lobbying group of physicians and medical students, health spending in the United States increased by 7.5% in 2023 to $4.9 trillion, or $14,570 per capita, higher than the 4.6% rise in 2022. Therefore, the rising healthcare expenditure is driving the growth of the avascular necrosis industry.

Key Players In The Global Avascular Necrosis Market

Major companies operating in the avascular necrosis market are Stryker Corporation, Massachusetts General Hospital, Zimmer Biomet Holdings Inc., Smith & Nephew plc, Stanford Health Care, Apollo Hospitals Enterprise Limited, Singapore General Hospital Pte Ltd., Fortis Healthcare Limited, Narayana Hrudayalaya Limited, Bumrungrad International Hospital Co. Ltd., Aster DM Healthcare Limited, Mount Elizabeth Hospital Pte Ltd., Gleneagles Hospital Pte Ltd., Shalby Limited, Texas Orthopedic Hospital LLC, Regrow Biosciences Pvt. Ltd., Maxcure Hospitals Limited, Medicover Hospitals Private Limited, Mesoblast Limited, Athersys Inc.

What Are Latest Mergers And Acquisitions In The Avascular Necrosis Market?

In January 2024, Enovis Corporation, a US-based provider of medical-technology solutions specializing in orthopaedic devices and surgical innovations, acquired LimaCorporate S.p.A. for approximately €800 million. With this acquisition, Enovis Corporation gains access to LimaCorporate’s advanced portfolio of joint-reconstruction implants, including its 3D-printed trabecular titanium technology and strong presence in the shoulder and hip reconstruction segments, thereby enhancing its reconstructive orthopaedics capabilities while improving its global scale, operational efficiency, and market reach. LimaCorporate S.p.A is an Italy-based provider of orthopaedic implant solutions and patient-specific digital and 3D-printed devices, known for its pioneering manufacturing expertise and innovative personalized reconstruction technologies.

Regional Insights

North America was the largest region in the avascular necrosis market in 2025. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in this market report are Asia-Pacific, South East Asia, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in this market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Taiwan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

What Defines the Avascular Necrosis Market?

The avascular necrosis market consists of revenues earned by entities by providing services such as radiology services, pharmacotherapy management services, long-term preventive treatment, and rehabilitation services. The market value includes the value of related goods sold by the service provider or included within the service offering. The avascular necrosis market also includes sales of products, including bone graft materials, orthopedic implants, C1 esterase inhibitors, and platelet-rich plasma kits. Values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

How is Market Value Defined and Measured?

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified). The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

What Key Data and Analysis Are Included in the Avascular Necrosis Market Report 2026?

The avascular necrosis market research report is one of a series of new reports from The Business Research Company that provides market statistics, including industry global market size, regional shares, competitors with the market share, detailed market segments, market trends and opportunities, and any further data you may need to thrive in the avascular necrosis industry. The market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future state of the industry.