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CAR-T Therapy Pipeline Analysis Global Market Report 2021: COVID 19 Growth And Change to 2030

Starting Price : $ 5000.00 | Pages : 175 | Published : January 2021 | SKU CODE : | Format :


The chimeric antigen receptor -T therapy market consists of sales of CAR-T therapy products and related services by entities (organizations, sole traders and partnerships) that develop chimeric antigen receptor (CAR) T-cell therapies to treat blood cancers. CAR-T therapy is type of immunotherapy in which T-cells taken from patient’s blood are modified in a laboratory with the addition of a special protein receptor that grants T-cells the power to recognize as well as kill cancer cells easily, along with infusing the same back into that patient. This special protein receptor, known as chimeric antigen receptor (CAR), attaches to a specific protein on a patient’s cancer cells. The infused cells multiply and prevail in the patient’s body as living drugs.

The global CAR-T therapy pipeline analysis market is expected to grow from $1.08 billion in 2020 to $1.4 billion in 2021 at a compound annual growth rate (CAGR) of 29.6%. The growth is mainly due to the companies resuming their operations and adapting to the new normal while recovering from the COVID-19 impact, which had earlier led to restrictive containment measures involving social distancing, remote working, and the closure of commercial activities that resulted in operational challenges. The market is expected to reach $3.15 billion in 2025 at a CAGR of 22%.

North America was the largest region in the global CAR-T therapy pipeline analysis market, accounting for 61% of the market in 2019. Western Europe was the second largest region accounting for 38% of the global market.

The CAR-T therapy market is driven by the increasing financial support provided by different organizations to promote the development and consumption of CAR-T therapy. The government and non-government organizations provide financial support to the companies in CAR-T therapy market for research and development and to the patients for their treatment of acute lymphoblastic leukaemia (ALL). For instance, in 2019, the Ministry of Business, Innovation and Employment of New Zealand announced its contribution of $4.9 million over 5 years to its partnership scheme with Malaghan Institute (MI), in order to support the development of CAR T-cell manufacturing in New Zealand. Further, governments in some countries provide subsidy to patients undergoing CAR-T therapy owing to the high cost of the treatment. For example, in 2019, the government of Australia included the CAR-T therapy on the Medicare Benefits Schedule (MBS). The inclusion of (Kymriah®) CAR-T therapy in MBS reduces the cost of the treatment for almost 30 paediatric and young adult (ALL) patients per year in Australia. The financial support provided by different organizations towards CAR-T therapy positively drives the growth of CAR-T therapy market.

The limitations on the application of CAR-T therapy limits the growth of the market. The limitations on CAR-T therapy includes its failure to treat other types of cancer, side effects and the high cost of treatment. CAR-T therapy is widely used as a treatment for a particular type of blood cancer and fails to treat other types of cancers such as lung cancer or breast cancer. Further, in many cases the application of CAR-T therapy results in cytokine release syndrome (CRS). CRS is severe flu like condition causing high fever, nausea, chills, headache, rash, and troubled breathing. Further, the high cost limits the growth of the market. According to an article in HealthLeaders in 2019, the cost of one CAR-T therapy session can be up to $375,000 excluding the overhead charges such as hospital bills. Thus, the growth of the CAR-T therapy is restricted by the various limitations on the application of CAR-T therapy.

The companies in the CAR-T therapy market are conducting clinical trials to assess the ability of CAR-T therapy to treat multiple myeloma. Multiple myeloma is a type of white blood cell cancer where the cancer cells accumulate in the bone marrow and surrounds the healthy blood cells. CAR-T therapy is being tested as a treatment for multiple myeloma. CAR-T cells are modified to target the multiple myeloma causing cells to treat the relapsed or refractory multiple myeloma (RRMM). For instance, Sorrento Therapeutics, a USA based developer of therapeutic approaches to treat different types of cancer, developed CAR2 anti-CD38 CAR-T cell therapy to treat RRMM. The CAR2 anti-CD38 CAR-T cell therapy is in phase 1 of its clinical trial with 72 participant recruitments made by the end of 2019.The aim of the clinical trial is to evaluate the efficiency and safety of CAR2 anti-CD38 CAR-T cell therapy. The trial is expected to be completed in 2020.

In 2019, Novartis, a Switzerland based global medicines company, acquired CellforCure for an undisclosed amount. The acquisition is aimed to increase Novartis' internal production capacity for cell and gene therapies. CellforCure is a French based contract development and manufacturing organization (CDMO) that provides manufacturing facility for cell and gene therapy. CellforCure assisted Novartis in 2017 to manufacture CAR-T treatment named Kymriah.

The major players covered in the global CAR-T therapy pipeline analysis market are Novartis AG, Kite Pharma, Pfizer Inc, Juno Therapeutics, Celgene Corporation, CARsgen Therapeutics, Sorrento Therapeutics, Legend Biotech, Mustang Bio, Immune Therapeutics, Atara Biotherapeutics, Aurora Biopharma Inc., Eureka Therapeutics, Autolus, TILT Biotherapeutics, Fortress Biotech., Autolus Therapeutics PLC, bluebird bio, Carina Biotech, CARTherics, Endocyte, Inc., F1 Oncology, Inc., Fate Therapeutics Inc., Gilead, Oxford BioMedica PLC., PeproMene Bio Inc., Tessa Therapeutics Pte Ltd., TILT Biotherapeutics Ltd.

The countries covered in the global CAR-T therapy pipeline analysis market are Brazil, China, France, Germany, India, Indonesia, Japan, South Korea, Russia, UK, USA, Australia.

The regions covered in the global CAR-T therapy pipeline analysis market are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

The global CAR-T therapy pipeline analysis market is segmented -

1) By Target Antigen: CD19, CD22, Others

2) By Application: Acute Lymphoblastic Leukemia,  Diffuse Large B-Cell Lymphoma, Follicular Lymphoma, Chronic Lymphocytic Leukemia, Multiple Myeloma, Others

    1. Executive Summary

    2. CAR-T Therapy Market Characteristics

    3. CAR-T Therapy Market Trends And Strategies

    4. Impact Of COVID-19 On CAR-T Therapy

    5. CAR-T Therapy Market Size And Growth

    5.1. Global CAR-T Therapy Historic Market, 2015-2020, $ Billion

    5.1.1. Drivers Of The Market

    5.1.2. Restraints On The Market

    5.2. Global CAR-T Therapy Forecast Market, 2020-2025F, 2030F, $ Billion

    5.2.1. Drivers Of The Market

    5.2.2. Restraints On the Market

    6. CAR-T Therapy Market Segmentation

    6.1. Global CAR-T Therapy Market, Segmentation  By Target Antigen, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion

    CD19

    CD22

    Others

    6.2. Global CAR-T Therapy Market, Segmentation  By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion

    Acute Lymphoblastic Leukemia  

     Diffuse Large B-Cell Lymphoma

    Follicular Lymphoma

    Chronic Lymphocytic Leukemia

    Multiple Myeloma  

    Others  

    7. CAR-T Therapy Market Regional And Country Analysis

    7.1. Global CAR-T Therapy Market, Split By Region, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion

    7.2. Global CAR-T Therapy Market, Split By Country, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion

    8. Asia-Pacific CAR-T Therapy Market  

    8.1. Asia-Pacific CAR-T Therapy Market Overview  

    Region Information, Impact Of COVID-19, Market Information, Background Information, Government Initiatives, Regulations, Regulatory Bodies, Major Associations, Taxes Levied, Corporate Tax Structure, Investments, Major Companies

    8.2. Asia-Pacific CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion

    9. China CAR-T Therapy Market  

    9.1. China CAR-T Therapy Market Overview  

    9.2. China CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F,$ Billion

    10. India CAR-T Therapy Market  

    10.1. India CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion

    11. Japan CAR-T Therapy Market  

    11.1. Japan CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion

    12. Australia CAR-T Therapy Market  

    12.1. Australia CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion

    13. Indonesia CAR-T Therapy Market  

    13.1. Indonesia CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion

    14. South Korea CAR-T Therapy Market  

    14.1. South Korea CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion

    15. Western Europe CAR-T Therapy Market  

    15.1. Western Europe CAR-T Therapy Market Overview

    15.2. Western Europe CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion

    16. UK CAR-T Therapy Market  

    16.1. UK CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion

    17. Germany CAR-T Therapy Market  

    17.1. Germany CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion

    18. France CAR-T Therapy Market  

    18.3. France CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion

    19. Eastern Europe CAR-T Therapy Market  

    19.1. Eastern Europe CAR-T Therapy Market Overview

    19.2. Eastern Europe CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion

    20. Russia CAR-T Therapy Market  

    20.1. Russia CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion

    21. North America CAR-T Therapy Market  

    21.1. North America CAR-T Therapy Market Overview

    21.2. North America CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion

    22. USA CAR-T Therapy Market  

    22.1. USA CAR-T Therapy Market Overview

    22.2. USA CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion

    23. South America CAR-T Therapy Market  

    23.1. South America CAR-T Therapy Market Overview

    23.2. South America CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion

    24. Brazil CAR-T Therapy Market  

    24.1. Brazil CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion

    25. Middle East CAR-T Therapy Market  

    25.1. Middle East CAR-T Therapy Market Overview

    25.2. Middle East CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion

    26. Africa CAR-T Therapy Market  

    26.1. Africa CAR-T Therapy Market Overview

    26.2. Africa CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion

    27. CAR-T Therapy Market Competitive Landscape And Company Profiles

    27.1. CAR-T Therapy Market Competitive Landscape

    27.2. CAR-T Therapy Market Company Profiles

    27.2.1. Novartis AG

    27.2.1.1. Overview

    27.2.1.2. Products and Services

    27.2.1.3. Strategy

    27.2.1.4. Financial Performance

    27.2.2. Kite Pharma

    27.2.2.1. Overview

    27.2.2.2. Products and Services

    27.2.2.3. Strategy

    27.2.2.4. Financial Performance

    27.2.3. Pfizer Inc

    27.2.3.1. Overview

    27.2.3.2. Products and Services

    27.2.3.3. Strategy

    27.2.3.4. Financial Performance

    27.2.4. Juno Therapeutics

    27.2.4.1. Overview

    27.2.4.2. Products and Services

    27.2.4.3. Strategy

    27.2.4.4. Financial Performance

    27.2.5. Celgene Corporation

    27.2.5.1. Overview

    27.2.5.2. Products and Services

    27.2.5.3. Strategy

    27.2.5.4. Financial Performance

    28. CAR-T Therapy Pipeline Analysis

    29. Key Mergers And Acquisitions In The CAR-T Therapy Market

    30. CAR-T Therapy Market Future Outlook and Potential Analysis

    31. Appendix

    31.1. Abbreviations

    31.2. Currencies

    31.3. Research Inquiries

    31.4. The Business Research Company

    31.5. Copyright And Disclaimer

List Of Tables

    Table 1: Global Historic Market Growth, 2015-2020, $ Billion
  • Table 2: Global Forecast Market Growth, 2020-2025F, 2030F, $ Billion
  • Table 3: Global CAR-T Therapy Market, Segmentation  By Target Antigen, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Table 4: Global CAR-T Therapy Market, Segmentation  By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Table 5: Global CAR-T Therapy Market, Split By Region, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Table 6: Global CAR-T Therapy Market, Split By Country, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Table 7: Asia-Pacific, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Table 8: China, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Table 9: India, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Table 10: Japan, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Table 11: Australia, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Table 12: Indonesia, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Table 13: South Korea, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Table 14: Western Europe, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Table 15: UK, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Table 16: Germany, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Table 17: France, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Table 18: Eastern Europe, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Table 19: Russia, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Table 20: North America, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Table 21: USA, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Table 22: South America, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Table 23: Brazil, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Table 24: Middle East, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Table 25: Africa, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Table 26: Novartis AG Financial Performance
  • Table 27: Kite Pharma Financial Performance
  • Table 28: Pfizer Inc Financial Performance
  • Table 29: Juno Therapeutics Financial Performance
  • Table 30: Celgene Corporation Financial Performance

List Of Figures

    Figure 1: Global Historic Market Growth, 2015-2020, $ Billion
  • Figure 2: Global Forecast Market Growth, 2020-2025F, 2030F, $ Billion
  • Figure 3: Global CAR-T Therapy Market, Segmentation  By Target Antigen, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Figure 4: Global CAR-T Therapy Market, Segmentation  By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Figure 5: Global CAR-T Therapy Market, Split By Region, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Figure 6: Global CAR-T Therapy Market, Split By Country, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Figure 7: Asia-Pacific, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Figure 8: China, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Figure 9: India, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Figure 10: Japan, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Figure 11: Australia, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Figure 12: Indonesia, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Figure 13: South Korea, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Figure 14: Western Europe, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Figure 15: UK, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Figure 16: Germany, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Figure 17: France, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Figure 18: Eastern Europe, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Figure 19: Russia, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Figure 20: North America, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Figure 21: USA, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Figure 22: South America, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Figure 23: Brazil, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Figure 24: Middle East, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Figure 25: Africa, CAR-T Therapy Market, Segmentation By Application, Historic and Forecast, 2015-2020, 2020-2025F, 2030F, $ Billion
  • Figure 26: Novartis AG Financial Performance
  • Figure 27: Kite Pharma Financial Performance
  • Figure 28: Pfizer Inc Financial Performance
  • Figure 29: Juno Therapeutics Financial Performance
  • Figure 30: Celgene Corporation Financial Performance
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