Closed System Transfer Devices Market Report 2026

Closed System Transfer Devices Market Overview

• Closed System Transfer Devices market size has reached to $1.18 billion in 2025 • Expected to grow to $2.18 billion in 2030 at a compound annual growth rate (CAGR) of 12.6% • Growth Driver: Rising Cancer Incidence Fueling Growth in the Closed System Transfer Devices Market • Market Trend: New EQUASHIELD® Syringe Unit Receives FDA Clearance, Enhancing Safety in Hazardous Drug Administration • North America was the largest region in 2025 and Asia-Pacific is the fastest growing region.

What Is Covered Under Closed System Transfer Devices Market?

Closed system transfer devices (CSTDs) are specialized drug transfer devices designed to mechanically prevent environmental contaminants from entering the system and to stop hazardous drugs or vapor concentrations from escaping. These devices create a closed, leak-proof system to ensure the safe handling of hazardous substances in healthcare environments. The main types of closed-system transfer devices are needleless systems, and membrane-to-membrane systems. Membrane-to-membrane systems denote a model lipid membrane system utilized in scientific research to investigate the characteristics and dynamics of biological membranes. The various technologies include diaphragm-based, compartmentalized, filtration with various closing mechanisms such as color-to-color alignment systems, push-to-turn systems, click-to-lock systems, and luer-lock systems. These are used by various end-users such as hospitals and clinics, oncology centers, and others.

What Is The Closed System Transfer Devices Market Growth Forecast?

The closed system transfer devices market size is expected to see rapid growth in the next few years. It will grow to $2.18 billion in 2030 at a compound annual growth rate (CAGR) of 12.6%. The growth in the forecast period can be attributed to stricter regulatory enforcement for hazardous drug handling, rising cancer treatment volumes, growing emphasis on workplace safety compliance, expansion of oncology centers globally, increasing investment in hospital pharmacy safety infrastructure. Major trends in the forecast period include rising adoption of closed drug handling systems in oncology, increasing focus on healthcare worker safety and exposure reduction, growing preference for needleless closed transfer systems, expansion of cstd usage across hospital pharmacies, increasing standardization of hazardous drug handling protocols.

What Is The Driver Of The Closed System Transfer Devices Market?

The increasing occurrence of cancer is expected to propel the growth of the closed-system transfer devices market going forward. Cancer is a disease characterized by an uncontrolled division of abnormal cells, which can invade nearby tissues and spread to other body parts through the blood and lymph systems. The cases of cancer are on the rise due to various factors, such as lifestyle factors, environmental exposures, and increased infections. Closed-system transfer devices are essential tools in cancer treatment, protecting healthcare workers and patients from the risks associated with handling and administering chemotherapy drugs. Their use contributes to a safer healthcare environment and better treatment outcomes for cancer patients. For instance, in February 2024, according to the World Health Organization (WHO), a Switzerland-based intergovernmental organization, by 2050 cancer cases are expected to exceed 35 million, representing a 77% increase from the estimated 20 million cases projected for 2022. This significant rise highlights the growing burden of cancer worldwide. Furthermore, in January 2023, according to the National Center for Biotechnology Information, a US-based intergovernmental organization, there were 1,958,310 new cancer cases in the United States and 609,820 cancer deaths are projected to occur in 2023. Therefore, increasing cancer cases drive the closed system transfer devices industry.

Key Players In The Global Closed System Transfer Devices Market

Major companies operating in the closed system transfer devices market are Cardinal Health Inc., Becton Dickinson and Company, Baxter International Inc., B Braun Melsungen AG, Terumo Corporation, ICU Medical Inc., Amsino International Inc., JMS Co. Ltd., Vygon SA, Codan Medical GmbH, Equashield LLC, Hospira Inc., Nipro Corporation, Simplivia Healthcare Ltd., Practivet Inc., Corvida Medical Inc., Yukon Medical, Caragen Ltd., Insung Medical Co. Ltd., Aegis Medical Technologies, Epic Medical Pte Ltd., Smiths Medical

Global Closed System Transfer Devices Market Trends and Insights

Major companies operating in the closed system transfer devices (CSTD) market are focusing on developing innovative syringe units to enhance safety, improve user experience, reduce the risk of contamination, and comply with stringent regulatory standards in the healthcare industry. A syringe unit for full volume use refers to a syringe designed to deliver or administer the complete volume of a liquid or medication it contains, without the need for additional mixing or dilution. For instance, in October 2023, Equashield, a US-based medical device company, launched the EQUASHIELD Syringe Unit, which has received FDA clearance for full-volume use, allowing for safer and more efficient handling of hazardous drugs. This innovative design prevents vapour from escaping and plunger contamination, making it a cost-effective solution for compounding and administering medications.

What Are Latest Mergers And Acquisitions In The Closed System Transfer Devices Market?

In December 2024, Equashield Medical Ltd., a US-based medical device company, partnered with Pharmacy Stars to enhance safety and compliance in medication compounding across healthcare facilities. Through this partnership, the companies aim to integrate EQUASHIELD’s hazardous drug-handling technologies with Pharmacy Stars’ Compounding360 platform to strengthen contamination control, streamline regulatory compliance, and improve operational efficiency for pharmacies. Pharmacy Stars is a US-based health tech company specializing in compounding quality management solutions.

What Defines the Closed System Transfer Devices Market?

The closed system transfer devices market consists of sales of closed vial access devices (CVADs), closed syringe transfer systems, closed bag systems, and closed ampoule systems. Values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

How is Market Value Defined and Measured?

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified). The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

What Key Data and Analysis Are Included in the Closed System Transfer Devices Market Report 2026?

The closed system transfer devices market research report is one of a series of new reports from The Business Research Company that provides market statistics, including industry global market size, regional shares, competitors with the market share, detailed market segments, market trends and opportunities, and any further data you may need to thrive in the closed system transfer devices industry. The market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future state of the industry.