Gene Synthesis Market Report 2026

Gene Synthesis Market Overview

• Gene Synthesis market size has reached to $3.95 billion in 2025 • Expected to grow to $10.44 billion in 2030 at a compound annual growth rate (CAGR) of 21.7% • Growth Driver: Rise In Biofuel Demand Is Anticipated To Fuel The Gene Synthesis Market • Market Trend: Innovative Services To Meet The Demand For Quicker Delivery • North America was the largest region in 2025 and Asia-Pacific is the fastest growing region.

What Is Covered Under Gene Synthesis Market?

Gene synthesis refers to chemically synthesizing a strand of DNA (deoxyribonucleic acid) base-by-base. Gene synthesis can be used for a variety of applications including creating recombinant DNA molecules, protein engineering, gene therapy, and synthetic biology. The main methods of gene synthesis include solid-phase synthesis, chip-based synthesis, and PCR-based enzyme synthesis. Solid-phase synthesis is the synthesis of chemical compounds whereby the reactant molecule is chemically bound to an insoluble material and reagents are added in the solution phase. It includes various gene synthesis services, such as antibody DNA synthesis, viral DNA synthesis, and others that are used in various applications such as gene and cell therapy development, vaccine development, disease diagnosis, and others. It is used by different end-users such as biotechnology and pharmaceutical companies, academic and government research institutes, and contract research organizations.

What Is The Gene Synthesis Market Growth Forecast?

The gene synthesis market size is expected to see exponential growth in the next few years. It will grow to $10.44 billion in 2030 at a compound annual growth rate (CAGR) of 21.7%. The growth in the forecast period can be attributed to rise in gene and cell therapy development, increasing investment in synthetic biology, growing vaccine development initiatives, expansion of contract research organizations, increasing use of viral dna synthesis in diagnostics. Major trends in the forecast period include expansion of synthetic biology applications, growth of personalized gene therapies, increased demand for high-fidelity dna synthesis, advancements in enzyme-based synthesis techniques, rising academic and government research initiatives.

Global Gene Synthesis Market Segmentation

1) By Method: Solid-Phase Synthesis, Chip-Based Synthesis, PCR-Based Enzyme Synthesis 2) By Service: Antibody DNA Synthesis, Viral DNA Synthesis, Other Services 3) By Application: Gene And Cell Therapy Development, Vaccine Development, Disease Diagnosis, Other Applications 4) By End-User: Biotechnology And Pharmaceutical Companies, Academic And Government Research Institutes, Contract Research Organizations Subsegments: 1) By Solid-Phase Synthesis: Phosphoramidite Method, H-phosphonate Method 2) By Chip-Based Synthesis: Microarray Technology, Light-Directed Synthesis 3) By PCR-Based Enzyme Synthesis: Polymerase Chain Reaction (PCR), Reverse Transcription PCR (RT-PCR)

What Is The Driver Of The Gene Synthesis Market?

The rise in biofuel demand is expected to propel the growth of the gene synthesis market going forward. A biofuel is a renewable energy source derived from organic materials, such as plants or animal waste, and used as an alternative to traditional fossil fuels. Gene synthesis is employed in biofuel production to engineer microorganisms with enhanced metabolic pathways for the efficient conversion of organic materials into biofuels. For instance, in June 2023, according to the International Energy Agency (IEA), a France-based intergovernmental organization, biofuel demand is projected to rise by 6%, or 5700 million liters, between 2022 and 2024 in advanced economies, with most of the increase occurring in the United States and Europe. Therefore, the rise in biofuel demand is driving the gene synthesis industry.

Key Players In The Global Gene Synthesis Market

Major companies operating in the gene synthesis market are Genscript Biotech Corporation, Twist Bioscience Corp., ProteoGenix Inc., Biomatik Corporation, ProMab Biotechnologies Inc., Thermo Fisher Scientific Inc., Integrated DNA Technologies Inc., OriGene Technologies Inc., GenScript Corp., Merck KGaA, Codex DNA Inc., Genewiz Inc., Eurofins Genomics LLC, BioCat GmbH, Bioneer Pacific Co. Ltd., Bio Basic Inc., Beijing SBS Genetech Co. Ltd, Creative Biogene Inc, Exonbio LLC., Trenzyme GmbH, Polygen GmbH, MACROGEN CO. LTD., Synbio Technologies LLC

Global Gene Synthesis Market Trends and Insights

Major companies in the gene synthesis market are focused on providing advanced platforms, such as silicon-based DNA synthesis platforms, to meet the demand for quicker delivery and gain a competitive edge in the market. A silicon-based DNA synthesis platform is a technology that utilizes silicon wafers to facilitate the miniaturization of the chemical reactions involved in creating DNA during the gene synthesis process. For instance, in November 2023, Twist Bioscience Corporation, a US-based biotechnology company, launched Twist Express Genes, a rapid gene synthesis service with a five to seven business days turnaround time. It utilizes a silicon-based DNA synthesis platform for meeting customer expectations with faster delivery. The Express Genes service aims to cater to researchers in industry and academia who both purchase DNA from suppliers and independently synthesize genes, providing a comprehensive solution for their gene production needs. GenScript guarantees plasmid yield and 100% sequence accuracy, maintaining high standards of quality and reliability in its offerings.

What Are Latest Mergers And Acquisitions In The Gene Synthesis Market?

In January 2023, Moderna Inc., a US-based biotechnology company acquired OriCiro Genomics. for an undisclosed amount. With the acquisition, OriCiro Genomics aims to enhance its capabilities in mRNA manufacturing and accelerate the development of its therapeutic and vaccine portfolio. OriCiro Genomics is a Japan-based biotechnology company that specializes in synthetic biology and DNA synthesis technologies.

Regional Insights

North America was the largest region in the gene synthesis market in 2025. Asia-Pacific is expected to be the fastest-growing region in the global gene synthesis market report during the forecast period. The regions covered in this market report are Asia-Pacific, South East Asia, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in this market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Taiwan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

What Defines the Gene Synthesis Market?

The gene synthesis market includes revenues earned by entities by providing custom gene synthesis services, selling pre-made DNA constructs, genetic engineering, vaccine development, antibody discovery, protein engineering, licensing technology, forming partnerships, and collaborating on research projects. The market value includes the value of related goods sold by the service provider or included within the service offering. Only goods and services traded between entities or sold to end consumers are included.

How is Market Value Defined and Measured?

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified). The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

What Key Data and Analysis Are Included in the Gene Synthesis Market Report 2026?

The gene synthesis market research report is one of a series of new reports from The Business Research Company that provides market statistics, including industry global market size, regional shares, competitors with the market share, detailed market segments, market trends and opportunities, and any further data you may need to thrive in the gene synthesis industry. The market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future state of the industry.