Spray-Dried Biologics Market Report 2026

Spray-Dried Biologics Market Overview

• Spray-Dried Biologics market size has reached to $1.86 billion in 2025 • Expected to grow to $3.2 billion in 2030 at a compound annual growth rate (CAGR) of 11.4% • Growth Driver: Increasing Demand For Biopharmaceuticals Fueling The Growth Of The Market Amid Rising Chronic And Complex Disease Burden • Market Trend: Integrating Drum Dosing Technology For Enhanced Performance • North America was the largest region in 2025 and Asia-Pacific is the fastest growing region.

What Is Covered Under Spray-Dried Biologics Market?

Spray-dried biologics are biologic drugs that have been transformed from a liquid into a dry powder using a rapid drying technique. The process works by spraying the liquid formulation into heated air, which quickly removes moisture while maintaining the integrity of delicate components such as proteins, vaccines, or enzymes. The resulting dry form offers advantages such as better stability, easier handling, and suitability for different delivery routes. The main product types of spray-dried biologics include monoclonal antibodies, vaccines, enzymes, hormones, and others. Monoclonal antibodies are laboratory-produced molecules designed to recognize and bind to a specific target antigen with high precision. The different routes of administration involved are oral, inhalation or pulmonary, injectable, and topical, and serve end-users such as hospitals, research institutes, pharmaceutical and biotechnology companies, and others.

What Is The Spray-Dried Biologics Market Growth Forecast?

The spray-dried biologics market size is expected to see rapid growth in the next few years. It will grow to $3.2 billion in 2030 at a compound annual growth rate (CAGR) of 11.4%. The growth in the forecast period can be attributed to increasing demand for non-injectable biologics, rising investments in dry powder delivery systems, expansion of global vaccine production, growing focus on cold-chain reduction, advancements in spray-drying equipment design. Major trends in the forecast period include increasing adoption of spray-drying for biologic stability, rising demand for inhalable and oral biologic formulations, expansion of continuous spray-drying processes, growing use of dry powder biologics in vaccines, enhanced focus on shelf-life extension.

Global Spray-Dried Biologics Market Segmentation

1) By Product Type: Monoclonal Antibodies, Vaccines, Enzymes, Hormones, Other Product Types 2) By Route Of Administration: Oral, Inhalation Or Pulmonary, Injectable, Topical 3) By End-User: Hospitals, Research Institutes, Pharmaceutical And Biotechnology Companies, Other End-Users Subsegments: 1) By Monoclonal Antibodies: Chimeric Antibodies, Humanized Antibodies, Fully Human Antibodies, Bispecific Antibodies, Antibody Fragments 2) By Vaccines: Live Attenuated Vaccines, Inactivated Vaccines, Subunit Vaccines, Toxoid Vaccines, Viral Vector Vaccines, Recombinant Protein Vaccines 3) By Enzymes: Therapeutic Enzymes, Digestive Enzymes, Metabolic Enzymes, Recombinant Enzymes, Replacement Enzymes 4) By Hormones: Peptide Hormones, Protein Hormones, Steroid Hormones, Recombinant Hormones, Growth Hormones 5) By Other Product Types: Blood Factors, Cytokines, Fusion Proteins, Nucleic Acid Therapeutics, Cell Culture Media Proteins

What Is The Driver Of The Spray-Dried Biologics Market?

Increasing demand for biopharmaceuticals is expected to propel the growth of the spray-dried biologics market going forward. Biopharmaceuticals are therapeutic products derived from biological sources, including living cells, proteins, and other biomolecules. Demand for biopharmaceuticals is rising due to the global surge in chronic and complex health conditions, which is creating a pressing need for therapies that offer higher specificity, improved efficacy, and fewer systemic side effects. The spray-dried biologics industry is experiencing growing demand as the rapid expansion of biopharmaceuticals drives companies to adopt scalable formulation technologies that improve stability, shelf life, and delivery efficiency. For instance, in February 2025, according to the World Health Organization (WHO), a Switzerland-based international public health agency, in 2023, the WHO essential medicines list (EML) included 81 biologic therapies, accounting for more than 15% of all essential medicines. Therefore, the increasing demand for biopharmaceuticals is driving the growth of the spray-dried biologics industry.

Key Players In The Global Spray-Dried Biologics Market

Major companies operating in the spray-dried biologics market are Thermo Fisher Scientific Inc., Evonik Industries AG, Lonza Group AG, GEA Group, Fareva Group, Almac Group Limited, Seqens Group, Fabbrica Italiana Sintetici S.p.A., CordenPharma International, Hovione FarmaCiencia SA, Veranova Inc., Pace Analytical Services LLC, Olon S.p.A., Nova Laboratories Ltd, Leukocare AG, Micro Sphere SA, Seran Bioscience LLC, CritiTech Particle Engineering Solutions LLC, Xedev BV, BÜCHI Labortechnik AG.

Global Spray-Dried Biologics Market Trends and Insights

Major companies operating in the spray-dried biologics market are focusing on incorporating technological advancements such as drum dosing technology to enhance dose accuracy, powder handling efficiency, and reliable large-scale capsule filling. Drum dosing technology is an advanced powder-filling method that uses a rotating drum with precision-engineered dosing cavities and vacuum-assisted transfer to accurately meter and deposit dry powders into capsules, enabling capabilities such as consistent low-dose filling, improved flow management of spray-dried powders, and high-throughput scalability. For instance, in February 2024, Catalent Inc., a US-based contract development and manufacturing organization (CDMO), upgraded its inhalation manufacturing facility in the US by adding potent capsule-filling capabilities powered by drum-based dosing systems and in-line advanced mass verification. The upgraded platform supports accurate filling of engineered and spray-dried powders, featuring real-time dose validation and controlled low-humidity processing. This enhancement improves manufacturing efficiency, product consistency, and readiness for commercial-scale production of spray-dried biologic dry-powder inhalation therapies.

What Are Latest Mergers And Acquisitions In The Spray-Dried Biologics Market?

In May 2023, Hovione, a Portugal-based integrated contract development and manufacturing organization (CDMO) specializing in spray drying and particle engineering, partnered with H&T Presspart to advance high-efficiency device technology for dry powder inhalation formulation delivery. Through this collaboration, Hovione aims to enhance its capabilities in engineered spray-dried and high-dose inhalation formulations by leveraging Presspart’s Sunriser capsule-based dry powder inhaler platform to improve the performance and commercial readiness of inhalation therapies. H&T Presspart is a Germany-based manufacturer of drug-delivery devices and components, specializing in inhalation device technology.

Regional Insights

North America was the largest region in the spray-dried biologics market in 2025. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in this market report are Asia-Pacific, South East Asia, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in this market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Taiwan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

What Defines the Spray-Dried Biologics Market?

The spray-dried biologics market consists of sales of peptide therapeutics, deoxyribonucleic acid vaccines, ribonucleic acid vaccines, nanobodies, antibody-drug conjugates, and recombinant proteins. Values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

How is Market Value Defined and Measured?

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified). The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

What Key Data and Analysis Are Included in the Spray-Dried Biologics Market Report 2026?

The spray-dried biologics market research report is one of a series of new reports from The Business Research Company that provides market statistics, including industry global market size, regional shares, competitors with the market share, detailed market segments, market trends and opportunities, and any further data you may need to thrive in the spray-dried biologics industry. The market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future state of the industry.