HERG Screening Market Report 2026

HERG Screening Market Overview

• HERG Screening market size has reached to $1.84 billion in 2025 • Expected to grow to $3.21 billion in 2030 at a compound annual growth rate (CAGR) of 11.7% • Growth Driver: Expanding HERG Screening Market Fueled By Increasing Prevalence Of Heart Disorders • Market Trend: Innovative GLP-Certified hERG Screening Solutions for Enhanced Cardiac Safety in Drug Development • North America was the largest region in 2025 and Asia-Pacific is the fastest growing region.

What Is Covered Under HERG Screening Market?

Human Ether-à-go-go-related gene (HERG) screening refers to the process of assessing the potential cardiotoxicity of a drug or compound. HERG screening is an important component of preclinical safety assessment in drug discovery and development, ensuring the safety and efficacy of novel therapeutic agents. The main types of HERG screening are gene KCNH2 and mutant KCNH2. The gene KCNH2, also known as the human ether-à-go-go-related gene hERG gene (hERG), encodes the alpha subunit of a potassium ion channel that plays a crucial role in regulating the electrical activity of the heart. It includes various ion channels, such as voltage-gated and ligand-gated, and is used in several applications, such as antiarrhythmics, antipsychotics, antibiotics, and others.

What Is The HERG Screening Market Growth Forecast?

The herg screening market size is expected to see rapid growth in the next few years. It will grow to $3.21 billion in 2030 at a compound annual growth rate (CAGR) of 11.7%. The growth in the forecast period can be attributed to advancements in ai-driven predictive toxicology, integration of organ-on-chip technologies, growth of biologics and personalized medicine, rising outsourcing to cdmos, expansion in emerging markets preclinical research. Major trends in the forecast period include advanced cardiotoxicity modeling, high-throughput screening automation, integration of predictive analytics in preclinical safety, expansion of contract research services, miniaturized microfluidic assays.

Global HERG Screening Market Segmentation

1) By Type: Gene KCNH2, Mutant KCNH2 2) By Ion Channel: Voltage-Gated, Ligand Gated 3) By Applications: Antiarrhythmic, Antipsychotic, Antibiotics, Other Applications Subsegments: 1) By Gene KCNH2: Wild-Type KCNH2, Recombinant KCNH2 2) By Mutant KCNH2: Mutations: Missense Mutations, Nonsense Mutations, Frameshift Mutations

What Are The Drivers Of The HERG Screening Market?

The rise in the number of patients with heart disorders is expected to propel the growth of the HERG screening market going forward. Heart disorders, also known as cardiovascular disorders or diseases, refer to a range of conditions that affect the heart and blood vessels. These conditions can impact the heart's ability to function properly and may lead to serious health complications. These disorders arise because of unhealthy lifestyles, an aging population, genetic factors, diabetes, and metabolic syndrome. HERG screening helps to identify potential drug candidates, prevent adverse cardiac events that could induce life-threatening cardiac arrhythmias, particularly torsade de pointes (TdP), and improve patient outcomes. For instance, in October 2025, according to the Australian Institute of Health and Welfare, an Australia-based government agency reported that in 2023, an estimated 57,100 adults aged 25 and above experienced acute coronary events, averaging roughly 156 incidents per day. Therefore, the rise in the number of patients with heart disorders is driving the growth of the HERG screening industry. The rise in aging population is expected to drive the growth of the HERG screening market going forward. An aging population refers to a growing proportion of older individuals within a society due to increased life expectancy and declining birth rates. The aging population is increasing due to advancements in healthcare that have extended life expectancy. HERG screening is used for the aging population by helping ensure new drugs are safe for elderly patients by identifying compounds that could cause harmful cardiac side effects. For instance, in January 2024, according to the Population Reference Bureau, a US-based non-profit organization, reported that the number of Americans aged 65 and older is expected to rise from 58 million in 2022 to 82 million by 2050, marking a 47% increase. As a result, this age group’s proportion of the total U.S. population will grow from 17% to 23% during this period. Therefore, the rise in aging population is driving the growth of the HERG screening industry.

Key Players In The Global HERG Screening Market

Major companies operating in the herg screening market are Eurofins-Cerep SA, Aviva Biosciences Inc., AstraZeneca Public Limited Company, Merck KGaA, Charles River Laboratories Inc., Abcam Public Limited Company, Molecular Devices LLC, Caliper Life Sciences Inc., ChanTest Corporation, Creative Bioarray Inc., Cellular Dynamics International Inc., Nanion Technologies, Essen Bioscience, ACEA Biosciences Inc., Metrion Biosciences Inc., Aurora Biomed Inc., Aureus Sciences, RedShift BioAnalytics, Sophion Bioscience Inc., Fluxion Biosciences Inc.

Global HERG Screening Market Trends and Insights

Major companies operating in the HERG screening market are concentrating on new innovative advanced solutions, such as GLP-certified HERG screening services, to enhance cardiac safety assessments during drug development processes. This service refers to the good laboratory practice-certified screening of the human ether-à-go-go related gene (hERG) using the conventional whole-cell patch-clamp technique. It ensures that the screening is conducted in compliance with regulatory guidelines such as ICH S7A and ICH S7B, which are essential for safety pharmacology studies in drug development. For instance, in August 2023, Metrion Biosciences Ltd., a UK-based pharmaceutical company, launched the good laboratory practice (GLP)-certified hERG screening service. This service aims to enhance Metrion's support for small-molecule therapeutic development and complement the company's existing cardiac safety service portfolio. Additionally, this service utilizes the conventional whole-cell patch-clamp technique to assess potential cardiac liabilities before entering Phase 1 clinical trials in humans, provides regulatory guidance for safety pharmacology studies in drug development, and offers clients high-quality biology services for ion channel targets.

Regional Insights

North America was the largest region in the HERG screening market in 2025. Asia-Pacific is expected to be the fastest growing region in the forecast period. The regions covered in this market report are Asia-Pacific, South East Asia, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in this market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Taiwan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

What Defines the HERG Screening Market?

The HERG screening market includes revenues earned by entities by providing services such as in vitro HERG assays, patch clamp electrophysiology, data analysis and interpretation, consultation and regulatory support, and customized assay development. The market value includes the value of related goods sold by the service provider or included within the service offering. Only goods and services traded between entities or sold to end consumers are included.

How is Market Value Defined and Measured?

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified). The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

What Key Data and Analysis Are Included in the HERG Screening Market Report 2026?

The herg screening market research report is one of a series of new reports from The Business Research Company that provides market statistics, including industry global market size, regional shares, competitors with the market share, detailed market segments, market trends and opportunities, and any further data you may need to thrive in the herg screening industry. The market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future state of the industry.