Immunohematology Market 2025

Immunohematology Market Definition

Immunohematology refers to the branch of medicine and diagnostics that focuses on the study of blood group antigens and antibodies to ensure safe and effective blood transfusion and management of immune-mediated blood disorders. This field encompasses a range of diagnostic methods, devices and reagents used to analyze and identify blood types, detect antibodies and manage conditions related to the immune response involving blood cells. The immunohematology market consists of sales, by entities (organizations, sole traders, or partnerships), of immunohematology that are utilized primarily when blood compatibility needs to be ensured, such as during pretransfusion testing, organ transplantation and investigation of immune-mediated hemolysis.

Immunohematology Market Size

The global immunohematology market reached a value of nearly $2,458.66 million in 2024, having grown at a compound annual growth rate (CAGR) of 3.24% since 2019. The market is expected to grow from $2,458.66 million in 2024 to $3,174.15 million in 2029 at a rate of 5.24%. The market is then expected to grow at a CAGR of 4.83% from 2029 and reach $4,108.45 million in 2034. Growth in the historic period resulted from the increasing prevalence of blood disorders, increase in infectious diseases, expanding healthcare expenditure, rise in trauma and accident cases and favorable government initiative and funding. Factors that negatively affected growth in the historic period were lack of skilled personnel. Going forward, increasing organ transplants and surgeries, emergence of personalized medicine, growing aging population and strong economic growth will drive the growth. Factor that could hinder the growth of the immunohematology market in the future include limited blood supply.

Immunohematology Market Drivers

The key drivers of the immunohematology market include: Increasing Organ Transplants and Surgeries Increasing organ transplants and surgeries is expected to be a key driver of the growth of the immunohematology market in the forecast period. The increasing prevalence of organ transplants has driven a heightened demand for rigorous blood typing and crossmatching to ensure donor-recipient compatibility. Immunohematology plays a critical role in this process by preventing immune rejection of transplanted organs. As the volume of organ transplants continues to grow, the demand for immunohematology testing has correspondingly increased, presenting significant opportunities for growth in this sector. For instance, in January 2023, the United Network for Organ Sharing, a US-based non-profit scientific and educational organization, reported that 42,887 organ transplants were performed in the United States in 2022, marking a 3.7 percent increase from 2021 and setting a new annual record. Furthermore, in April 2022, according to the National Library of Medicine, a US-based biomedical library, globally, 2.6 million people undergo renal replacement therapy, including dialysis or kidney transplants, a number that is projected to double by 2030. Therefore, the increasing number of organ transplants and surgeries will drive demand for immunohematology going forward.

Immunohematology Market Restraints

The key restraints on the immunohematology market include: Limited Blood Supply The limited blood supply is expected to limit the growth of the immunohematology market in the forecast period. Immunohematology depends on a reliable and sufficient supply of donated blood for both testing and transfusion purposes. Insufficient donation rates can result in shortages, impairing the ability to conduct essential diagnostic procedures such as blood typing, antibody screening and crossmatching. For instance, in May 2024, according to the report Journal of Korean Medical Science published by the Korean Academy of Medical Sciences, a South Korea-based organization dedicated to advancing medical science and research, the blood supply is projected to decline from 2.6 million units in 2021 to 1.4 million units by 2050. Therefore, limited blood supply may hinder the growth of the immunohematology market.

Immunohematology Market Trends

Major trends shaping the immunohematology market include: Next-Generation Blood Processing System With Cutting-Edge Automation Major companies operating in the immunohematology market are focusing on developing next-generation blood processing systems with cutting-edge automation. The system enhances blood supply management by automating the process of separating whole blood into its components, making blood processing faster, more reliable and more efficient, which ultimately benefits hospitals and patients in need of blood transfusions. For instance, in October 2024, Terumo Blood and Cell Technologies, a US-based provider of blood management solutions, launched the Reveos Automated Blood Processing System in the United States, in partnership with Blood Centers of America, a US-based cooperative representing community blood centers. This cutting-edge system is engineered to streamline blood processing by automating the separation of whole blood into its components, such as platelets, plasma and red blood cells—within a single centrifugation cycle. These components are vital in transfusion medicine. The first deployment of the system will take place at Carter BloodCare in Texas, to enhance blood supply management and optimize operational efficiency across blood centers nationwide. Optimizing Blood Testing Processes With Advanced Multiplex Analysis Companies operating in the immunohematology market focus on transforming blood transfusion management with advanced multiplex analysis. This technology enables high-resolution analysis of blood samples, allowing for more comprehensive and accurate results while reducing the need for multiple individual tests. It optimizes the testing process by grouping various parameters in one step, improving the efficiency and throughput of blood testing. For instance, in June 2024, Innobiochips, a France-based biotechnology company, introduced Omnys, an advanced solution designed to optimize blood transfusion, grouping and testing processes. This innovative system significantly improves laboratory efficiency by enabling multiplex analysis with high-resolution testing of blood components, such as ABO (major blood group system) /D typing (Rh factor) and phenotyping, while reducing the number of wells required from 16 to just 4-6. The Omnys incorporates multiple patented technologies, streamlining operations, minimizing waste and reducing the carbon footprint associated with blood testing. A beta testing program for Omnys is scheduled to begin in early 2025, offering blood banks and healthcare institutions an opportunity to assess its integration into transfusion workflows.

Opportunities And Recommendations In The Immunohematology Market

Opportunities – The top opportunities in the immunohematology markets segmented by product will arise in the reagents segment, which will gain $407.42 million of global annual sales by 2029. The top opportunities in the immunohematology market segmented by technology will arise in the polymerase chain reaction (PCR) segment, which will gain $310.72 million of global annual sales by 2029. The top opportunities in the immunohematology markets segmented by disease will arise in the blood-related diseases segment, which will gain $477.18 million of global annual sales by 2029. The top opportunities in the immunohematology markets segmented by application will arise in the pretransfusion testing segment, which will gain $324.77 million of global annual sales by 2029. The top opportunities in the immunohematology markets segmented by end user will arise in the hospitals segment, which will gain $306.08 million of global annual sales by 2029. The immunohematology market size will gain the most in USA at $241.59 million. Recommendations- To take advantage of the opportunities, The Business Research Company recommends the immunohematology companies to focus on developing next-generation blood processing systems, focus on advancing multiplex blood testing technology, focus on the fastest-growing analyzers and systems segment, focus on biochips for accelerated growth, focus on blood-related diseases for market expansion, focus on pretransfusion testing to drive growth, expand in emerging markets, focus on expanding distribution channels for market growth, focus on developing competitive and value-based pricing strategies, focus on digital marketing strategies to enhance brand authority for immunohematology companies, focus on strategic partnerships with key opinion leaders to build credibility for immunohematology companies and focus on hospitals to drive growth in the immunohematology market.