Intraoperative Radiotherapy (IORT) Market Report 2026

Intraoperative Radiotherapy (IORT) Market Overview

• Intraoperative Radiotherapy (IORT) market size has reached to $1.08 billion in 2025 • Expected to grow to $1.75 billion in 2030 at a compound annual growth rate (CAGR) of 10.1% • Growth Driver: Rising Prevalence Of Cancers Fueling The Market Growth Due To Increasing Life Expectancy • Market Trend: Advancements In Intraoperative Radiation Delivery Technologies • North America was the largest region in 2025 and Asia-Pacific is the fastest growing region.

What Is Covered Under Intraoperative Radiotherapy (IORT) Market?

Intraoperative radiotherapy (IORT) is a specialized cancer treatment technique in which a single, high dose of ionizing radiation is delivered directly to a tumor or tumor bed during surgery, immediately after the tumor is removed. It enables precise targeting of cancerous tissue while minimizing radiation exposure to surrounding healthy organs and may reduce the need for additional external radiotherapy in selected patients. The main product types of intraoperative radiotherapy (IORT) include systems, applicators and afterloaders, and accessories. Systems refer to specialized radiotherapy equipment used to deliver targeted radiation directly to a tumor bed during surgery, helping treat residual cancer cells while minimizing radiation exposure to surrounding healthy tissue. These devices are available as cart-mounted intraoperative radiotherapy devices, floor-mounted fixed intraoperative radiotherapy devices, and robotic-arm-assisted intraoperative radiotherapy devices and use technologies such as electron intraoperative radiation therapy, X-ray intraoperative radiation therapy, and other technologies. They find application in breast cancer, brain tumor, gastrointestinal cancer, head and neck cancer, and others, serving end users including hospitals, ambulatory surgical centers, specialty clinics, and others.

What Is The Intraoperative Radiotherapy (IORT) Market Growth Forecast?

The intraoperative radiotherapy (IORT) market size is expected to see rapid growth in the next few years. It will grow to $1.75 billion in 2030 at a compound annual growth rate (CAGR) of 10.1%. The growth in the forecast period can be attributed to growing demand for personalized cancer treatment, increasing need for reduced radiation exposure to healthy tissue, rising adoption of intraoperative treatment technologies, expanding availability of specialized oncology centers, growing demand for single-session radiation therapy. Major trends in the forecast period include increasing adoption of single-session cancer treatment approaches, rising demand for precise intraoperative radiation delivery, growing use of compact radiation therapy systems, increasing demand for integrated treatment planning and dosimetry, rising adoption of minimally invasive cancer treatment procedures.

What Is The Driver Of The Intraoperative Radiotherapy (IORT) Market?

The rising prevalence of cancer is expected to propel the growth of the intraoperative radiotherapy (IORT) market going forward. Cancer is a group of diseases where abnormal cells grow uncontrollably, invade tissues, and can spread to other parts of the body. The cancer prevalence is increasing due to aging population, as advanced age is the most significant risk factor for developing most types of cancer, with the majority of cases occurring in individuals over 65 years old. Intraoperative radiotherapy (IORT) enhances cancer treatment by delivering a concentrated dose of radiation directly to the tumor bed during surgery, improving treatment precision, minimizing exposure to surrounding healthy tissues, and reducing the risk of local cancer recurrence. For instance, in February 2024, according to the World Health Organization, a Switzerland-based international organization specializing in global health policy and public health initiatives, over 35 million new cancer cases are predicted in 2050, a 77% increase from the estimated 20 million cases in 2022. Therefore, the rising prevalence of cancer is driving the growth of the intraoperative radiotherapy market.

Key Players In The Global Intraoperative Radiotherapy (IORT) Market

Major companies operating in the intraoperative radiotherapy (iort) market are Thales Electron Devices SAS, Siemens Healthineers AG, Hologic Inc., Carl Zeiss Meditec AG, Elekta AB, Eckert & Ziegler Radiopharma GmbH, GMV Innovating Solutions S.L., Mevion Medical Systems Inc., Sensus Healthcare Inc., Tema Sinergie S.p.A., iCAD Inc., Xstrahl Ltd., IntraOp Medical Corporation, BEBIG Medical GmbH, S.I.T. Sordina IORT Technologies S.p.A.

Global Intraoperative Radiotherapy (IORT) Market Trends and Insights

Major companies operating in the intraoperative radiotherapy (IORT) market are focusing on developing innovative solutions, such as advanced intraoperative radiation delivery technologies, to enhance treatment precision, reduce radiation exposure to healthy tissues, and improve cancer treatment outcomes. Advanced intraoperative radiation delivery technologies are innovative systems that enable precise, real-time delivery of radiation directly to a tumor or tumor bed during surgery, minimizing damage to surrounding healthy tissues and improving treatment accuracy. For instance, in October 2024, Aster DM Quality Care Limited, an India-based healthcare company, launched Intra-Operative Electron Radiation Therapy (IOeRT) at the Aster International Institute of Oncology, Aster Whitefield Hospital, Bengaluru, becoming the first healthcare institution in India to introduce this technology. The IOeRT system delivers concentrated electron radiation immediately after tumor removal, targeting residual microscopic cancer cells while sparing adjacent healthy tissues. It is particularly suitable for treating breast, gastrointestinal, lung, pancreatic, gynecologic, and soft tissue cancers where precision is critical. The technology shortens overall treatment time by potentially replacing multiple postoperative radiation sessions with a single intraoperative dose, reduces radiation-related side effects, and supports faster patient recovery while improving local tumor control.

What Are Latest Mergers And Acquisitions In The Intraoperative Radiotherapy (IORT) Market?

In October 2023, Elekta AB, a Sweden-based medical technology company, acquired Xoft, a business line of iCAD, Inc., for $5.5 million. With this acquisition, Elekta aims to expand its brachytherapy portfolio and treatment applications by adding electronic brachytherapy capabilities, increasing access to precision cancer treatments, and strengthening its ability to serve a wider range of oncology clinics and patients globally. Xoft is a US-based medical technology company that offers intraoperative radiotherapy (IORT) solutions for targeted radiation delivery during cancer surgery.

What Defines the Intraoperative Radiotherapy (IORT) Market?

The intraoperative radiotherapy (IORT) market consists of sales of mobile electron linear accelerator (LINAC) systems, low-energy X-ray intraoperative radiotherapy systems, and intraoperative radiotherapy applicators and treatment cones. Values in this market are ‘factory gate’ values, that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

How is Market Value Defined and Measured?

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified). The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

What Key Data and Analysis Are Included in the Intraoperative Radiotherapy (IORT) Market Report 2026?

The intraoperative radiotherapy (iort) market research report is one of a series of new reports from The Business Research Company that provides market statistics, including industry global market size, regional shares, competitors with the market share, detailed market segments, market trends and opportunities, and any further data you may need to thrive in the intraoperative radiotherapy (iort) industry. The market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future state of the industry.