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Small Molecule Drug Discovery Industry Report 2025: Market Overview, Trends & Competitive Landscape

22 May, 2025

The Small Molecule Drug Discovery Market Overview 2025 report reveals that the market size has grown significantly over the past few years, with projections indicating further expansion.

What are the Historical Growth Trends in the Small Molecule Drug Discovery Market?

The Small Molecule Drug Discovery market has experienced significant expansion lately. The market value is projected to rise from $62.44 billion in 2024 to $68.57 billion in 2025, with a Compound Annual Growth Rate (CAGR) of 9.8%.

What are the 2025 Market Projections: Forecasted Size & Growth Rate for the Small Molecule Drug Discovery Industry?

The Small Molecule Drug Discovery market is projected to expand to a size of $106.91 billion by the year 2029, growing at a Compound Annual Growth Rate (CAGR) of 11.7%.

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What are the Key Growth Drivers Fueling the Small Molecule Drug Discovery Market?

The key drivers in the small molecule drug discovery market are:

• Emergence of novel therapeutic targets
• Implementation of patient-centric drug discovery methods
• Integration of pharmacogenomics in drug discovery
• Increasing global health challenges fueling the need for new drugs.

Global Market Segmentation: Identifying Major Small Molecule Drug Discovery Industry Segments

The small molecule drug discovery market covered in this report is segmented –
1) By Drug Type: Small Molecule Drugs, Biologic Drugs
2) By Technology: High Throughput Screening, Pharmacogenomics, Combinatorial Chemistry, Nanotechnology, Others
3) By Therapeutic Area: Oncology, Central Nervous System, Cardiovascular, Respiratory, Metabolic Disorders, Gastrointestinal, Others
4) By Process Or Phase: Target ID Or Validation, Hit Generation And Selection, Lead Identification, Lead Optimization
5) By End-User: Pharmaceutical Companies, Contract Research Organizations, Others

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What are the Emerging Trends Shaping the Future of the Small Molecule Drug Discovery Market?

The key trends in the small molecule drug discovery market are:

• The drug-discovery market is gravitating towards the use of artificial intelligence and fragment-based methods.
• The advancements in pharmacogenomics integration and RNA-targeted therapeutics are strongly influencing the market trends.
• Innovations in drug delivery systems, such as drug-device combination products, are becoming more prominent.
• A significant trend is the incorporation of organoids and 3D cell culture models, as well as a rise in collaborations and partnerships in drug discovery.

Who Are the Top Competitors & Leading Players in the Small Molecule Drug Discovery Market?

Major companies in the small molecule drug discovery market are:

• Pfizer Inc.
• GlaxoSmithKline plc
• AstraZeneca
• Boehringer Ingelheim International GmbH
• Bristol-Myers Squibb Company
• Johnson & Johnson
• Gilead Sciences Inc.
• Merck KGaA
• Novartis AG
• 4SC AG
• Teva Pharmaceutical Industries Ltd.
• Takeda Pharmaceutical Company Limited
• Labcorp Drug Development
• ICON Public Limited Company
• Charles River Laboratories
• Aluda Pharmaceuticals
• Clinuvel Pharmaceuticals
• Corcept Therapeutics
• Edison Oncology
• Escend Pharmaceuticals
• Terray Therapeutics
• Apollomics
• Astex Pharmaceuticals
• Pardes Biosciences
• Xynomic Pharmaceuticals
• Zevra Therapeutics
• UNION therapeutics
• Pharmacosmos
• Allarity Therapeutics
• Xellia Pharmaceuticals
• Cyteir Therapeutics
• BigHat Biosciences

Regional Dominance: Which Area Leads the Global Template Market?

North America was the largest region in the small molecule drug discovery market in 2024

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