The Treatment-Resistant Depression Market Overview 2025 report reveals that the market size has grown significantly over the past few years, with projections indicating further expansion.
The market size of the treatment-resistant depression sector has seen robust growth lately. The market size is projected to increase from $1.76 billion in 2024 to $1.88 billion in 2025, with a compound annual growth rate (CAGR) of 7.1%.
The Treatment-Resistant Depression Global Market is expected to grow to a size of $2.46 billion by 2029, with a forecasted compound annual growth rate (CAGR) of 6.9%.
Download Your Free Sample of the 2025 Treatment-Resistant Depression Market Report and Uncover Key Trends Now!The key drivers in the Treatment-Resistant Depression market are:
• Increase in chronic diseases and prevalence of anxiety disorders
• Growing awareness of mental health and government initiatives
• Expansion of telemedicine and digital health
• Advancements in diagnostic and therapeutic technologies and adoption of personalized medicine
The treatment-resistant depression market covered in this report is segmented –
1) By Drug Class: Selective Serotonin Reuptake Inhibitors (SSRIS), Monoamine Oxidase Inhibitors, Tricyclic Antidepressant, Psychedelics, Other Drug Classes
2) By Route Of Administration: Oral, Parenteral, Other Routes Of Administration
3) By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies
4) By End-User: Hospitals, Homecare, Specialty Clinics, Other End-Users
The key trends in the Treatment-Resistant Depression market are:
• The expansion of telemedicine and digital health is emerging as a prominent trend.
• The market is being shaped by advancements in diagnostic and therapeutic technologies.
• There's an increasing trend towards mental health awareness and stigma reduction.
• The adoption of personalized medicine and use of artificial intelligence are significant emerging trends.
Major companies in the Treatment-Resistant Depression market are:
• Pfizer Inc.
• Johnson & Johnson Services Inc.
• Abbott Laboratories
• Novartis AG
• GlaxoSmithKline (GSK) plc.
• Hikma Pharmaceuticals plc
• Neurocrine Biosciences Inc.
• Relmada Therapeutics Inc.
• Neuronetics Inc.
• COMPASS Pathways
• Lykos Therapeutics
• Reviva Pharmaceuticals
• Celon Pharma SA
• BrainsWay Ltd.
• Magstim Company Limited
• MindMed
• Alto Neuroscience
• Sage Therapeutics Inc.
• MindBio Therapeutics Ltd.
• Reunion Neuroscience
North America was the largest region in the treatment-resistant depression market in 2024