The Acute On Chronic Liver Failure (ACLF) Market Overview 2025 report reveals that the market size has grown significantly over the past few years, with projections indicating further expansion.
The market size for acute on chronic liver failure (ACLF) has witnessed a substantial increase in the recent past. The ACLF market is forecasted to expand from $2.68 billion in 2024 to $2.89 billion in 2025, growing at a Compound Annual Growth Rate (CAGR) of 8.0%.
The Acute On Chronic Liver Failure (ACLF) market is predicted to grow to a market size of $3.89 billion by 2029. The expected compound annual growth rate (CAGR) is 9.8%.
Download Your Free Sample of the 2025 Acute On Chronic Liver Failure (ACLF) Market Report and Uncover Key Trends Now!The key drivers in the acute on chronic liver failure (aclf) market are:
• Rising adoption of liver support devices and advancements in regenerative medicine
• Increasing focus on precision medicine and growing demand for minimally invasive treatments
• Growing prevalence of metabolic disorders and greater investment in research and development
• Expansion of healthcare infrastructure in emerging markets and increasing public-private partnerships.
The acute on chronic liver failure (ACLF) market covered in this report is segmented –
1) By Type Of Treatment: Pharmacological, Supportive Care
2) By Mode Of Administration: Oral, Intravenous (IV)
3) By End-User: Hospitals, Ambulatory Surgical Centers, Specialty Clinics
Subsegments:
1) By Pharmacological: Antibiotics, Anti-inflammatory Drugs, Vasopressors, Immunomodulators, Antiviral Agents
2) By Supportive Care: Liver Dialysis, Plasma Exchange, Nutritional Support, Mechanical Ventilation, Renal Replacement Therapy (RRT)
The key trends in the acute on chronic liver failure (aclf) market are:
• The integration of artificial intelligence in ACLF diagnostics is a significant emerging trend.
• There is an increase in the development of bioengineered liver tissue and extracorporeal liver support devices.
• Advances in gene editing technologies and targeted drug delivery systems are shaping the future of the market.
• Progress in 3D bioprinting for liver regeneration and advancements in nanotechnology-based therapies are key trends.
Major players in the acute on chronic liver failure (aclf) market are:
• Pfizer Inc.
• F. Hoffmann-La Roche AG
• Merck & Co. Inc.
• Bayer AG
• Sanofi S.A.
• Bristol-Myers Squibb
• AstraZeneca plc
• Abbott Laboratories
• GSK plc
• Eli Lilly and Company
• Gilead Sciences Inc
• Novo Nordisk A/S
• Astellas Pharma Inc.
• CSL Behring
• Grifols S.A.
• Lupin Pharmaceutical Limited
• Ferring Pharmaceuticals
• Shire plc
• Gyre Therapeutics Inc.
• Dr. Falk Pharma GmbH
• Genfit
• eGenesis Inc.
• Conatus Pharmaceuticals Inc.
• Cellaion SA
• Rheacell GmbH & Co. KG
• Martin Pharmaceuticals Inc.
North America was the largest region in the acute on chronic liver failure (ACLF) market in 2024