The Adenosine Deaminase-Severe Combined Immunodeficiency Market Overview 2025 report reveals that the market size has grown significantly over the past few years, with projections indicating further expansion.
The market size of adenosine deaminase-severe combined immunodeficiency has been experiencing significant expansion in the past years. The market is projected to increase from $5.57 billion in 2024 to $5.95 billion in 2025, with a compound annual growth rate (CAGR) of 6.9%.
The Adenosine Deaminase-Severe Combined Immunodeficiency Global Market is predicted to grow to $7.70 billion in 2029, at a CAGR of 6.6%.
Download Your Free Sample of the 2025 Adenosine Deaminase-Severe Combined Immunodeficiency Market Report and Uncover Key Trends Now!The key drivers in the adenosine deaminase-severe combined immunodeficiency market are:
• Rising prevalence of genetic disorders
• Increasing use of bone marrow transplantation
• Growing demand for non-conditioned stem cell transplantation
• Rising number of adenosine deaminase deficiency cases
The adenosine deaminase-severe combined immunodeficiency market covered in this report is segmented –
1) By Treatment Type: Enzyme Replacement Therapy (ERT), Gene Therapy, Stem Cell Transplantation, Supportive Care Treatments
2) By Route of Administration: Intravenous, Subcutaneous, Oral
3) By Age Group: Pediatric (Infants and Children), Adults
4) By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies
5) By End-User: Hospitals, Specialty Clinics, Research Institutes, Others End-Users
Subsegments:
1) By Enzyme Replacement Therapy (ERT): Adenosine Deaminase Enzyme Replacement, Pegylated Erythropoietin (PEG-EPO)
2) By Gene Therapy: Autologous Stem Cell-Based Gene Therapy, Viral Vector-Mediated Gene Therapy
3) By Stem Cell Transplantation: HLA-Matched Bone Marrow Transplant, Umbilical Cord Blood Transplant
4) By Supportive Care Treatments: Antimicrobial Therapy, Immune System Support, Nutritional Support
The key trends in the adenosine deaminase-severe combined immunodeficiency market are:
• Technological advancements are a major emerging trend in the adenosine deaminase-severe combined immunodeficiency market.
• There is a growing shift toward the adoption of gene therapy practices.
• Advanced genetic testing is becoming increasingly influential in this market.
• Governments are introducing initiatives and biotechnology is progressing, shaping the future of the market.
Major players in the adenosine deaminase-severe combined immunodeficiency market are:
• Novartis AG
• GlaxoSmithKline plc (GSK)
• Astellas Pharma
• Orient EuroPharma
• Charles River Laboratories
• Chiesi Farmaceutici S.p.A.
• Spark Therapeutics
• Rocket Pharmaceuticals
• Bluebird Bio
• Ospedale San Raffaele (OSR)
• Oxford Biomedica PLC
• Teijin Pharma
• Leadiant Biosciences
• Orchard Therapeutics PLC
• Fondazione Telethon
• Mustang Bio Inc
• Sigma-Tau Pharmaceuticals
• Shenzhen Geno-Immune Medical Institute
• ENZON Pharmaceuticals
• QED Bioscience Inc.
North America was the largest region in the adenosine deaminase-severe combined immunodeficiency market in 2024