The biodefense market has seen considerable growth due to a variety of factors.
• The biodefense market has grown strongly in recent years. It will rise from $18.55 billion in 2024 to $20.29 billion in 2025, at a CAGR of 9.4%.
Key factors behind this growth include heightened government investment in biodefense programs, strengthened regulatory frameworks to fast-track biodefense product approvals, enhanced collaboration between governments, private sectors, and academic institutions, and increasing concerns over bioterrorism and geopolitical tensions.
The biodefense market is expected to maintain its strong growth trajectory in upcoming years.
• The biodefense market is expected to grow to $28.75 billion by 2029, at a CAGR of 9.1%.
Growth is attributed to emerging infectious diseases, biotech breakthroughs, stronger international collaboration and funding, upgrading biodefense infrastructure, growing public awareness, evolving policies, and increased private sector investment. Key trends include AI and machine learning for predictive modeling, threat detection, next-gen vaccines and therapeutics, AI-driven drug discovery, and improved genomic surveillance.
The recurrent threat of emerging infectious diseases is expected to spur the growth of the biodefense market. These diseases, caused by microorganisms like viruses and bacteria, highlight the need for effective preparedness and rapid response. Biodefense measures, which focus on early detection and response, are vital in managing these health threats. For example, the WHO estimated 10.6 million cases of tuberculosis worldwide in 2022, underscoring the growing demand for biodefense solutions.
The biodefense market covered in this report is segmented –
1) By Type: Anthrax, Smallpox, Botulism, Radiation Or Nuclear, Other Types
2) By Biothreat Detection Device: Samplers, Detectors Or Triggering Devices, Identifiers, Assays, Other Biothreat Detection Devices
3) By Application: Hospitals And Clinics, Ambulatory Care Centers, Other Applications
Subsegments:
1) By Anthrax: Bacillus Anthracis Vaccine, Anthrax Therapeutics
2) By Smallpox: Smallpox Vaccine, Antiviral Drugs For Smallpox
3) By Botulism: Botulism Antitoxin, Botulism Vaccine, Botulinum Neurotoxin Inhibitors
4) By Radiation Or Nuclear: Radiation Protection Drugs, Medical Countermeasures
5) By Other Types: Ricin, Plague, Tularemia, Viral Hemorrhagic Fevers, Other Biotoxins Or Biothreat Agents
Companies in the biodefense market are innovating solutions such as nasal COVID-19 vaccines to strengthen global preparedness against biological threats. Nasal vaccines offer easier administration, potential mucosal immunity, and less reliance on needles, improving accessibility and immune response. For instance, in January 2023, Bharat Biotech International Limited from India launched the iNCOVACC Nasal COVID-19 vaccine, using a recombinant adenovirus vector and pre-fusion stabilized spike protein. The vaccine, after successful clinical trials, is administered as nasal drops in a two-dose series, providing a user-friendly alternative to traditional injections.
Major companies operating in the biodefense market are:
• Pfizer Inc.
• Johnson & Johnson
• Merck & Co.
• Sanofi SA
• Bristol-Myers Squibb Company
• AstraZeneca Plc
• GSK plc
• Gilead Sciences Inc
• Biogen Inc
• Novavax Inc
• Ichor Medical Systems
• Emergent BioSolutions Inc.
• Alnylam Pharmaceuticals Inc.
• Dynavax Technologies
• Bavarian Nordic
• Siga Technologies Inc.
• Elusys Therapeutics Inc.
• Ology Bioservices
• Altimmune Inc.
• Hytest Limited
• XOMA Corporation
• Cleveland BioLabs Inc.
• Inovio Pharmaceuticals Inc
• Dynport Vaccine Company
• ViralClear Pharmaceuticals
North America was the largest region in the biodefense market in 2023. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the biodefense market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.