The bone grafts and substitutes market has seen considerable growth due to a variety of factors.
• In the last few years, the market size for bone grafts and substitutes has experienced robust growth. The market value is projected to accelerate from $3.39 billion in 2024 to $3.58 billion in 2025, reflecting a compound annual growth rate (CAGR) of 5.7%.
The growth witnessed in the previous years can be credited to the heightened demand for orthopedic medical tools, growing disability rates, a surge in joint replacement surgeries, increased healthcare spending, and solid economic progress in emerging markets.
The bone grafts and substitutes market is expected to maintain its strong growth trajectory in upcoming years.
• Anticipated robust expansion is foreseen in the bone grafts and substitutes market in the coming years, with projections indicating a growth to $4.53 billion in 2029, reflecting a compound annual growth rate (CAGR) of 6.0%.
This ascension during the prediction window is credited to an increasing elderly population, a spike in road mishaps and sports-related injuries, a surge in joint reconstruction disorder requirements, and a growing number of amputations due to diabetes. Key trends during this forecast span will include the introduction of new products, the advent of 3D-printed bone grafts, and a string of partnerships and collaborations.
The escalating occurrence of musculoskeletal ailments such as osteoporosis and tendonitis is anticipated to accelerate the expansion of the bone grafts and substitutes market. Such disorders are injuries and conditions that impede the musculoskeletal system and movement of the human body, affecting muscles, nerves, tendons, joints, cartilage, and spinal discs. Consequently, the surge in these disorders triggers a higher demand for bone grafts and substitutes in the market. To illustrate, a Pediatric Orthopedic Consultant at the Indian Spinal Injuries Centre, Delhi, reported a 50% increase in Pediatric Orthopedic Cases in March 2022, attributed to students' poor posture during online classes. As a result, the growing rates of musculoskeletal disorders contribute to the heightened demand in the bone grafts and substitutes market.
The bone grafts and substitutes market covered in this report is segmented –
1) By Material: Allograft, Synthetic, Xenograft
2) By Application: Spinal Fusion, Trauma, Craniomaxillofacial, Joint Reconstruction, Dental Bone Grafting, Other Applications
3) By End User: Hospitals And Clinics, Surgical Centers, Other End-Users
Subsegments:
1) By Allograft: Demineralized Bone Matrix (DBM), Fresh Frozen Allografts, Freeze-Dried Allografts
2) By Synthetic: Ceramic-Based, Polymer-Based, Composite-Based, Bone Morphogenetic Proteins (BMPs)
3) By Xenograft: Bovine-Derived Grafts, Porcine-Derived Grafts, Other Animal-Derived Sources
Innovations in new products are emerging as a leading trend in the bone grafts and substitutes market, driven by key market players striving to meet consumer needs with their innovative offerings. A case in point is BONESUPPORT, a medical technology firm based in Sweden, which, in June 2023, introduced CERAMENT G. This updated version of an antibiotic-eluting bone graft substitute boasts improved usability, less environmental impact and a longer shelf life. Despite these enhancements, it retains identical composition, mode of action, and clinical results as earlier versions, but with notable advancements. The revamped kit is 28% more compact and features sterilized, ready-to-use components for a smoother surgical workflow and heightened surgical team efficiency. Furthermore, the product’s lifespan has been extended to three years, offering additional convenience.
Major companies operating in the bone grafts and substitutes market include:
• Medtronic plc
• Stryker Corporation
• Smith & Nephew
• Johnson & Johnson
• Zimmer Biomet
• Baxter International Inc.
• SeaSpine
• Integra Lifesciences Holdings Corporation
• NuVasive Inc.
• Orthofix Holdings Inc.
• Bioconcept Dental Implants
• NovaBone India
• Straumann
• Kamal Medtech
• Geistlich Bio-Oss
• Lindare Medical
• Hospital Innovations
• Bioimplon
• Exabone GmbH
• Mathys AG
• Dentsply Sirona Inc
• Danaher Corp
• Arthrex Inc
• Graftys
• Osseocon Biomateriais
• Einco Biomaterial
• Bionnovation
• Medbone Biomaterials
• CoreBone
• Datum Dental
• OK Coral
• Dentakay Dental Clinic
• Turkeyana Clinic
• Keystone Dental
• Allosource
• DePuy Synthes
• Wright Medical Group N.V.
North America was the largest region in the bone grafts and substitutes market in 2024. The regions covered in the bone grafts and substitutes market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.