What Transformation Has the Downstream Processing Market Undergone?
The downstream processing market has seen considerable growth due to a variety of factors.
•In recent times, the downstream processing market has seen speedy expansion. Forecasts indicate an increase from $31.26 billion in 2024 to $35.54 billion in 2025, reflecting a compound annual growth rate (CAGR) of 13.7%.
The historic period's development can be linked to factors such as increasing biopharmaceutical investments, strict regulatory norms, the globalization of biopharmaceutical production, and the climbing occurrence of chronic diseases.
How Will The Downstream Processing Market Size Evolve In The Foreseeable Future?
The downstream processing market is expected to maintain its strong growth trajectory in upcoming years.
• The market size for downstream processing is predicted to expand rapidly in the ensuing years. The projection indicates that this market will escalate to "$58.96 billion by 2029 with a Compound Annual Growth Rate (CAGR) of 13.5%.
This expected expansion in the projection period can be attributed to the growing demand for biopharmaceuticals, focus on green and sustainable processing, alliances and partnerships, the rise in the adoption of continuous bioprocessing, and the surge in the need for personalized medicines. Influential trends in the projection era include digitization and integration of industry 4.0, advancements in technology, adoption of single-use systems, growth of the biopharmaceutical industry, and a transition toward continuous processing.
What Are The Essential Drivers Behind The Growth Of The Downstream Processing Market?
Anticipated growth in the downstream processing market is linked to the projected rise in healthcare spending. Healthcare expenses encompass all costs associated with healthcare services, emergency health aid, nutrition programs, and family planning activities; such spending also fuels downstream processing sales. This process aids the recovery and purification of drug substances from natural sources including bacterial and animal cells, thereby facilitating drug manufacture. Reports from the Centers for Medicare & Medicaid Services, a branch of the U.S. Department of Health and Human Services, forecast that average yearly national health spending will rise by 5.1% between 2021 and 2030, essentially hitting roughly $6.8 trillion by 2030, based on data from the National Health Expenditure (NHE) report released in March 2022. Spending on Medicare and Medicaid is also projected to rise, with annual increments of 7.2% and 5.6% respectively, throughout the 2021-2030 period. Consequently, higher healthcare spending is fostering the expansion of the downstream processing market.
How Is The Global Downstream Processing Market Divided Into Key Segments?
The downstream processing market covered in this report is segmented –
1) By Product: Centrifuges, Dryers, Chromatography Systems, Filters, Evaporators, Other Products
2) By Technique: Purification Techniques, Solid-Liquid Separation, Clarification Or Concentration
3) By Application: Monoclonal Antibody Production, Vaccine Production, Insulin Production, Immunoglobulin Production, Erythropoietin Production, Other Applications
Subsegments:
1) By Centrifuges: Analytical Centrifuges, Preparative Centrifuges
2) By Dryers: Spray Dryers, Freeze Dryers, Fluidized Bed Dryers
3) By Chromatography Systems: Liquid Chromatography Systems, Gas Chromatography Systems, Affinity Chromatography Systems
4) By Filters: Membrane Filters, Depth Filters, Cartridge Filters
5) By Evaporators: Thin Film Evaporators, Forced Circulation Evaporators, Falling Film Evaporators
6) By Other Products: Mixers, Precipitation Systems, Storage Tanks
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What Trends Are Reshaping The Future Of The Downstream Processing Market?
Product innovations are increasingly becoming the dominant trends in the downstream processing market. Top businesses active in this market are focusing on creating new tech solutions to firmly establish their standing in the market. In a notable instance, Tosoh Bioscience LLC, a US-based global chemical, and specialty materials firm, took the initiative to unveil the Octave BIO Multi-Column Chromatography (MCC) system in September 2022. This comprehensive multi-column chromatography solution was meticulously crafted for the intensification of biomolecule purification procedures and is tuned for process development and validation. The adaptable modular design allows for a wide variety of requirements and also brings the benefits of resin and buffer cost savings inherent in MCC, among other tangible advantages.
Who Are the Key Players in the Downstream Processing Market?
Major companies operating in the downstream processing market include:
• Sartorius AG
• General Electric Company
• Merck KGaA
• Thermo Fisher Scientific Inc.
• Danaher Corporation
• Repligen Corporation
• Lonza Group Ltd.
• Eppendorf AG
• Corning Corporation
• Ashai Kasei Corporation
• Finesse Solutions Inc.
• MilliporeSigma
• Pall Corporation
• Bio-Rad Laboratories
• Charles River Laboratories International Inc.
• Waters Corporation
• Becton Dickinson and Company (BD)
• Entegris Inc.
• Novasep
• Avantor Sciences
• Tecan Group
• Agilent Technologies
• Boehringer Ingelheim International GmbH
• Ahlstrom-Munksjö Oyj
• Grifols S.A.
• GenScript Biotech Corporation
What are the Regional Insights into the Downstream Processing Market?
North America was the largest region in the downstream processing market in 2024.Asia-Pacific is expected to be the fastest-growing region in the global downstream processing market report during the forecast period. The regions covered in the downstream processing market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa
