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Global G-Protein Coupled Receptors Market Growth Rate 2025, Forecast To 2034

4 Mar, 2025

How Has the G-Protein Coupled Receptors Market Size Evolved in Recent Years?

The g-protein coupled receptors market has seen considerable growth due to a variety of factors.
•In recent times, we have seen a significant expansion in the G-protein coupled receptors market. From 2024 to 2025, it is expected to increase from $3.2 billion to $3.41 billion, marking a compound annual growth rate (CAGR) of 6.6%.
The factors contributing to this remarkable rise during the historical period include advances in drug discovery, approvals from the FDA, genomic discoveries, the development of emerging markets, market consolidation, as well as the increasing aging population.

What are the Market Size and Expected Growth Rates for the G-Protein Coupled Receptors Market?

The g-protein coupled receptors market is expected to maintain its strong growth trajectory in upcoming years.
• Anticipated robust expansion is on the horizon for the G-protein coupled receptors market, with projections predicting it will rise to $4.46 billion by 2029, boasting a compound annual growth rate (CAGR) of 7.0%.
Factors such as personalized medicine, a shift towards rare diseases, the application of artificial intelligence in drug discovery, patient-focused drug development, and environmental and social elements, as well as the growth of the biosimilar market, are all contributors to this projected growth during the predicted period. Noteworthy trends that are expected to emerge during this timeframe include progress in biotechnology, amplified research & development investment, technological breakthroughs, and increased collaborations and partnerships, as well as the rise of digital therapeutics.

Which Drivers Are Accelerating Growth In The G-Protein Coupled Receptors Market?

The increasing occurrence of cancer is anticipated to fuel the expansion of the G-protein-coupled receptors market in the future. Cancer represents a disease where irregular cells are capable of infecting adjacent tissues and spreading without regulation. The body's lymphatic and vascular systems are additional pathways through which cancer cells may disseminate. GPCRs manage processes recognized as cancer's defining traits, such as proliferative signaling, replicative immortality, evasion of growth inhibitors, resistance against apoptosis, and the triggering of invasion and metastasis. For example, in January 2023, the American Cancer Society, a professional organization based in the US, reported 1,958,310 new cancer cases diagnosed in the US during 2023. This is a rise from the projected 1.9 million new cases in 2022. As such, the escalating occurrence of cancer is stimulating the G-protein coupled receptors market's growth.

What Are The Core Segments Of The Global G-Protein Coupled Receptors Market?

The G-protein coupled receptors market covered in this report is segmented –
1) By Product: Cell Lines, Detection Kits, Cell Culture Reagents, Ligands
2) By Assay: CAMP Functional Assays, Calcium Functional Assays, ß-Arrestin Functional Assays, Radioligand Binding And GTP?S Functional Assays, Internalization Assays, Trafficking Assays
3) By Applications: Cancer Research, CNS Research, Metabolic Research, Cardiovascular Research, Inflammation Research, Respiratory Research, Other Applications Subsegments:
1) By Cell Lines: GPCR-Expressing Cell Lines, Stable And Transient Cell Lines
2) By Detection Kits: ELISA Kits, High-Throughput Screening Kits, Reporter Gene Assays
3) By Cell Culture Reagents: Media And Supplements, Transfection Reagents, Growth Factors
4) By Ligands: Agonists, Antagonists, Inverse Agonists

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Which Emerging Trends Are Reshaping The G-Protein Coupled Receptors Market Size?

The key trend increasingly gaining traction in the G-protein-coupled receptor (GPCR) market is the investment for the enhancement of GPCR screening and antibody creation. The primary players in the GPCR market are aiming to secure funding for the production of medicines and medical technologies that deal with GPCR-related ailments. In detail, LifeArc Ventures, a venture capital firm based in the UK, funded Maxion Therapeutics, a UK-based pharmaceutical discovery business, with a $16 million investment in February 2023. This will expedite the creation of antibody-based treatments for previously incurable ion channel and GPCR-driven disorders using their exclusive KnotBody technology. The KnotBody platform permits the unearthing of biologicals directed at ion channels and GPCRs using naturally present cysteine-rich mini proteins. Additionally, Septerna Inc., a biotech company founded in the U.S., publicized its inception and the procurement of Series A funding valued at $100 million. This Series A investment will fund the development of their evolving assortment of inventive programs focused on GPCR through the use of the Native Complex Platform spanning several therapeutic domains.

Who Are the Key Players in the G-Protein Coupled Receptors Market?

Major companies operating in the G-protein coupled receptors market include:
• Pfizer Inc.
• Roche Holding AG
• AbbVie Inc.
• Bayer AG
• Novartis International AG
• Sanofi SA
• Bristol-Myers Squibb Company
• AstraZeneca Plc
• GlaxoSmithKline Plc
• Danaher Corporation
• Takeda Pharmaceutical Company Limited
• Eli Lilly and Company
• Merck KGaA
• Boehringer Ingelheim
• Teva Pharmaceutical Industries Ltd.
• Daiichi Sankyo Company Limited
• Thermo Fisher Scientific Inc.
• Perkin Elmer Inc.
• Qiagen N.V.
• Bio-Techne Corporation
• Abcam PLC
• Cara Therapeutics Inc.
• Sosei Heptares Ltd.
• Eurofins DiscoverX Corporation
• Crinetics Pharmaceuticals Inc.
• Domain Therapeutics SA
• Addex Pharmaceuticals Ltd.
• Escient Pharmaceuticals Inc.
• Structure Therapeutics
• Septerna

What are the Regional Insights into the G-Protein Coupled Receptors Market?

North America was the largest region in the G-protein coupled receptors market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the G-protein coupled receptors market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.