The graft versus host disease (gvhd) treatment market has seen considerable growth due to a variety of factors.
• The graft versus host disease (GVHD) treatment market has shown strong growth in recent years. It will grow from $2.85 billion in 2024 to $3.07 billion in 2025, reflecting a compound annual growth rate (CAGR) of 7.7%.
This growth is linked to the rising number of allogeneic transplantations, an increase in acute GVHD cases, higher rates of hematopoietic stem cell treatment, greater demand for bone marrow transplants, and advancements in technology.
The graft versus host disease (gvhd) treatment market is expected to maintain its strong growth trajectory in upcoming years.
• The graft versus host disease (GVHD) treatment market is expected to grow steadily, reaching $4.1 billion by 2029, with a CAGR of 7.5%.
The market’s growth will be driven by more allogeneic transplantations, a higher incidence of acute GVHD, rising use of hematopoietic stem cell treatments, greater demand for bone marrow transplants, and increasing GVHD prevalence globally. Key trends include partnerships, investments, product approvals, and customizations.
The rise in hematological disorders is expected to fuel the growth of the graft versus host disease (GVHD) treatment market. Hematological disorders, including leukemia and lymphoma, are linked to unhealthy lifestyles, genetic factors, and environmental exposures. GVHD treatments help manage immune responses and offer broader applications for blood-related disorders. In 2023, the Leukemia & Lymphoma Society estimated that blood cancers would cause 57,380 deaths in the U.S., supporting the growth of the GVHD treatment market.
The graft versus host disease (GVHD) treatment market covered in this report is segmented –
1) By Product Type: Corticosteroids, Monoclonal Antibodies, Immunosuppressants, Others
2) By Disease Type: Acute GvHD, Prophylaxis GvHD, Chronic GvHD
3) By End User: Hospitals Pharmacies, Retail Pharmacies, Online Pharmacies
Subsegments:
1) By Corticosteroids: Prednisolone, Methylprednisolone, Dexamethasone, Hydrocortisone, Betamethasone, Budesonide
2) By Monoclonal Antibodies: Anti-Inf Monoclonal Antibodies ( Infliximab, Adalimumab), Anti-il-2ra Monoclonal Antibodies ( Basiliximab), Anti-cd52 Monoclonal Antibodies (Alemtuzumab), Anti-il-6 Monoclonal Antibodies (Tocilizumab), Anti-Cd20 Monoclonal Antibodies (Rituximab)
3) By Immunosuppressants: Calcineurin Inhibitors (Cyclosporine, Tacrolimus), Methotrexate, Mycophenolate Mofetil, Azathioprine, Sirolimus (Rapamycin), Cyclophosphamide
4) By Others: Mesenchymal Stem Cells (Mscs), Jak Inhibitors ( Ruxolitinib), Extracorporeal Photopheresis (Ecp), Thalidomide, Antithymocyte Globulin (Atg), Colony-Stimulating Factors (Filgrastim)
Major firms active in the graft versus host disease (GVHD) treatment market are striving to create superior drugs and gain regulatory approval in a bid to outshine competitors. Securing product approvals is crucial, as it ensures healthcare items meet the required safety, efficacy, and quality standards. An example of this is in March 2023 when Incyte Corporation, a healthcare firm based in the US, developed ruxolitinib extended-release (XR) tablets. Given the nod by the US-based Food and Drug Administration, these JAK1/JAK2 inhibitor tablets were designed for daily use in treating specific cases of myelofibrosis, polycythemia vera, and graft-versus-host disease (GVHD).
Major companies operating in the graft versus host disease (GVHD) treatment market are:
• Pfizer Inc.
• Johnson & Johnson Services Inc.
• F. Hoffmann-La Roche Ltd.
• Merck & Co. Inc.
• Sanofi SA
• Novartis AG
• Bristol Myers Squibb
• AstraZeneca
• Abbott Laboratories
• GlaxoSmithKline plc
• Eli Lilly And Company
• Novo Nordisk A/S
• Takeda Pharmaceutical Company Limited
• Gilead Sciences Inc.
• Merck KGaA
• Teva Pharmaceutical Industries Ltd.
• Biogen Inc.
• Astellas Pharma Inc.
• Jazz Pharmaceuticals plc
• Allergan plcIncyte Corporation
• Mallinckrodt Pharmaceuticals
• Genzyme Corporation
• Kiadis Pharma
• Neovii Pharmaceuticals AG
• ElsaLys Biotech SA
• Mesoblast Ltd.
• Soligenix
North America was the largest region in the graft versus host disease (GVHD) treatment market in 2023. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the graft versus host disease (GVHD) treatment market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.