The hypercholesterolemia market has seen considerable growth due to a variety of factors.
• In recent times, the market size for hypercholesterolemia has witnessed a significant surge. Its expansion is anticipated to go from $16.30 billion in 2024 to $18.66 billion in 2025, showcasing a compound annual growth rate (CAGR) of 14.5%.
The historic growth phase can be related to the surge of health campaigns, intensified research, and development, an increased emphasis on preventive healthcare, the expansion of preventive health screenings, and modifications in lifestyle.
The hypercholesterolemia market is expected to maintain its strong growth trajectory in upcoming years.
• Over the coming years, a rapid expansion is anticipated in the hypercholesterolemia market. The market is predicted to reach $31.70 billion in 2029, with a compound annual growth rate (CAGR) of 14.2%.
This anticipated growth during the forecast period can be credited to enhanced diagnosis and screening methods, government-led initiatives, and health policies, an increase in risk factors prevalence, rising accessibility of over-the-counter (OTC) products that lower cholesterol levels, and an elevated understanding of cholesterol risks. Key trends identified for the forecast period include innovative lipid profiling, the use of robotics in surgeries, the application of nanotechnology in drug delivery, telemedicine platforms, and lipoprotein targeting.
The escalation of cardiovascular illnesses is anticipated to boost the hypercholesterolemia market's progression. Cardiovascular diseases, a collection of disorders impacting the heart and blood vessels, are on the rise due to factors such as unhealthy eating habits, lack of physical activity, increasing obesity, chronic stress, aging communities, and the incidence of hypertension and diabetes. Hypercholesterolemia treatments aid cardiovascular patients by decreasing LDL cholesterol levels, lessening the buildup of arterial plaque, enhancing blood circulation, and minimizing the risk of heart attacks, strokes and other cardiovascular issues. For instance, in October 2024, data from the Centers for Disease Control and Prevention of the United States revealed that around 805,000 people experience a heart attack every year, with 605,000 being first-time incidents and the remaining 200,000 occurring in individuals who have past heart attack records. Hence, the rise in cardiovascular diseases is anticipated to be the catalyst for the hypercholesterolemia market's growth.
The hypercholesterolemia market covered in this report is segmented –
1) By Disease Type: Genetic, Acquired
2) By Treatment: Statins, Bile Acid Resins, Niacin, PCSK9 Inhibitors, Cholesterol Absorption Inhibitors, Fibric Acid Derivatives, Other Treatments
3) By Route Of Administration: Oral, Injectable
4) By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Others Distribution Channel
5) By End User: Hospitals, Specialty Clinics, Home Healthcare, Others End Users
Subsegments:
1) By Genetic: Heterozygous Familial Hypercholesterolemia, Homozygous Familial Hypercholesterolemia
2) By Acquired: Primary Hypercholesterolemia, Secondary Hypercholesterolemia
Key players in the hypercholesterolemia market are working on developing groundbreaking products, one such example being a triple-combination drug, to augment the efficiency of treatment and encourage patient adherence. A triple-combination drug infuses three functional ingredients into a single dosage form, like a capsule or a tablet. For instance, in February 2025, a novel hypertension-hyperlipidemia medication named Amrozet Tablet was introduced in the market by Celltrion Pharm, Inc., a pharmaceutical conglomerate from South Korea. The drug amalgamates three primary ingredients namely amlodipine for hypertension, rosuvastatin for cholesterol reduction and ezetimibe for hindering cholesterol absorption in the intestines. Available in four distinct dosage combinations such as 5/5/10 mg, 5/10/10 mg, 10/5/10 mg, and 10/10/10 mg, this drug is mainly indicated for hypertension and myocardial ischemia under amlodipine, and primary hypercholesterolemia under the combination of rosuvastatin-ezetimibe. Additionally, it can also be used for relieving chronic stable angina or vasospastic angina, and significantly reducing the likelihood of hospitalization because of angina and heart surgery in patients diagnosed with coronary artery disease.
Major companies operating in the hypercholesterolemia market are:
• Pfizer Inc.
• Merck & Co Inc.
• Abbvie Inc.
• Bayer AG
• Sanofi S.A.
• AstraZeneca PLC
• Novartis AG
• GlaxoSmithKline plc (GSK)
• Eli Lilly and Company
• Amgen Inc.
• Viatris Inc.
• Aegerion Pharmaceuticals Inc.
• Fresenius Kabi AG
• Sun Pharmaceutical Industries Ltd.
• Chiesi Farmaceutici S.p.A.
• Aurobindo Pharma Limited
• Dr. Reddy's Laboratories Ltd.
• Lupin Limited
• Ionis Pharmaceuticals Inc.
• Melinta Therapeutics Inc.
• NewAmsterdam Pharma N.V.
• HDL Therapeutics Inc.
North America was the largest region in the hypercholesterolemia market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the hypercholesterolemia market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.