How Has The In Situ Hybridization Market Size Evolved In Recent Years?
The in situ hybridization market has seen considerable growth due to a variety of factors.
•The market size for in situ hybridization has seen robust growth in the past few years. The market is projected to increase from $1.68 billion in 2024 to $1.83 billion in 2025, with a compound annual growth rate (CAGR) of 8.9%.
The surge during the historical period can be linked to its early adoption in scientific research, the advancement of molecular biology tools, growth in diagnostic applications, a refocus in biomedical research, and a rise in investment within the biotechnology sector.
What Is The Projected Growth Of The In Situ Hybridization Market?
The in situ hybridization market is expected to maintain its strong growth trajectory in upcoming years.
• The market size for in situ hybridization is anticipated to witness substantial expansion in the forthcoming years, escalating to a valuation of "$2.79 billion by 2029, with a compound annual growth rate (CAGR) of 11.2%.
Factors contributing to the growth during the forecast period include its growing usage in clinical diagnostics, the rise in research and development funding, the advent of automation and high-throughput solutions, and broadened applications in the fields of neuroscience and pathology. The forecast period will likely observe trends such as progressions in molecular biology, enhanced demand in research applications, expansion of diagnostic applications, rising interest in personalized medicine, and amplified investments in biomedical research.
What Are The Key Drivers Fueling Growth In The In Situ Hybridization Market?
The escalation in the number of infectious diseases is anticipated to fuel the expansion of the in-situ hybridization market. Infectious diseases are illnesses that can be transmitted from one person to another through contaminated food and drinks and via pathogens such as viruses, bacteria, fungi, and parasites. In-situ hybridization (ISH) utilizes labeled nucleic acid sequences (probes) that are specific to the infection-causing organism, aiming to detect matching nucleic acid sequences in the tissue. Hence, a rise in infectious diseases leads to the growth of the in-situ hybridization market. For instance, the Centers for Disease Control and Prevention, a US government agency, stated in March 2024 that tuberculosis cases surged from 8,320 in 2022 to 9,615 in 2023, marking an increase of 1,295 cases. Consequently, the escalating occurrence of infectious diseases is bolstering the expansion of the in-situ hybridization market.
What Are The Principal Market Segments In The Global In Situ Hybridization Industry?
The in situ hybridization market covered in this report is segmented –
1) By Product: Analytical Instruments, Kits and Reagents, Software and Services, Other Products
2) By Technique: Fluorescence In Situ Hybridization (FISH), Chromogenic In Situ hybridization (CISH)
3) By Probe: Deoxyribonucleic Acid (DNA), Ribonucleic Acid (RNA)
4) By Application: Cancer, Cytogenetics, Developmental Biology, Infectious Diseases, Other Applications
5) By End Use: Research And Diagnostic Laboratories, Contract Research Organization (CROs), Academic Institutes, Other End Uses
Subsegments:
1) By Analytical Instruments: Fluorescence Microscopes, Imaging Systems, Hybridization Systems
2) By Kits and Reagents: Hybridization Kits, Detection Kits, Probes And Reagents
3) By Software and Services: Image Analysis Software, Data Management Software, Consulting And Support Services
4) By Other Products: Accessories, Control Samples, Maintenance Supplies
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Which Emerging Market Trends Are Altering The In Situ Hybridization Sector?
Leading corporations in the in situ hybridization industry are concentrating on the development of novel solutions such as RNA detection assays with a view to revolutionize gene therapy. The RNA detection assay, a molecular method that identifies and measures specific RNA molecules in a given sample, aids in studying gene expression, viral infections and other processes related to RNA. For example, Bio-Techne Corporation, a life sciences firm based in the US, introduced the RNAscope Plus smRNA-RNA detection assay in January 2023. This is a sophisticated in situ hybridization tool that simultaneously facilitates fluorescent detection of small regulatory RNAs like microRNAs (miRNAs) and three target RNAs or RNA biomarkers within the same tissue section. The assay facilitates single-cell and subcellular resolution, making it possible for researchers to effectively evaluate the biodistribution and functionality of innovative gene therapies and endogenous regulatory RNAs. The assay is scalable, designed for large scale studies, and is compatible with the Leica Bond Rx platform or can be manually executed. By incorporating exclusive RNAscope and miRNAscope techniques, this assay considerably amplifies knowledge of gene expression and cellular responses, offering essential insights towards the development of bespoke gene therapies for both inherited and acquired diseases.
Who Are the Key Players in the In Situ Hybridization Market?
Major companies operating in the in situ hybridization market include:
• Thermo Fisher Scientific Inc.
• Bio SB Inc.
• BioGenex Laboratories
• Advanced Cell Diagnostics Inc.
• Exiqon A/S
• Agilent Technologies Inc.
• F. Hoffmann-La Roche AG
• Abbott Laboratories Inc.
• Merck KGaA
• PerkinElmer Inc.
• Biocare Medical LLC
• Genemed Biotechnologies
• Danaher Corporation
• Leica Biosystems Nussloch GmbH
• Bio-Rad Laboratories Inc.
• Oxford Gene Technology
• Abnova Corporation
• Qiagen
• Bio-Techne Corporation
• Biochain Institute Inc.
• Cytocell Ltd.
• Enzo Life Sciences Inc.
• Eurofins Scientific SE
• FISH Technologies Sdn Bhd
• Genetix Biotech Asia Pvt. Ltd.
• Zytomed System GmbH
• Akoya Biosciences Inc.
• Becton Dickinson and Company (BD)
• DAKO Systemtechnik und Service GmbH & Co
• Molecular Devices LLC.
• NanoString Technologies Inc.
• Visiopharm A/S
What are the Regional Insights into the In Situ Hybridization Market?
North America was the largest region in the in situ hybridization market in 2024. Asia-Pacific is expected to be the fastest-growing region in the global in situ hybridization market during the forecast period. The regions covered in the in situ hybridization market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa
