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Global In-Vitro Lung Model Report 2025, Forecast To 2034

25 Mar, 2025

What Fueled The Previous Growth In The In-Vitro Lung Model Market?

The in-vitro lung model market has seen considerable growth due to a variety of factors.
• The in-vitro lung model market has witnessed significant growth in recent years. It will expand from $0.44 billion in 2024 to $0.54 billion in 2025, reflecting a CAGR of 21.3%.
This growth is attributed to the increasing prevalence of respiratory diseases, the focus on personalized medicine, rising interest in drug repurposing, the emphasis on precision medicine, and greater awareness of environmental health risks.

What Is The Expected Growth In The In-Vitro Lung Model Market Size Evolve over the Forecast Period?

The in-vitro lung model market is expected to maintain its strong growth trajectory in upcoming years.
• The in-vitro lung model market is expected to grow exponentially, reaching $1.16 billion by 2029, with a CAGR of 21.0%.
The growth is driven by increasing drug development, the rise in preclinical testing, awareness of respiratory toxicology, regenerative medicine focus, growing environmental concerns, and an aging population. Major trends include increased drug testing demand, advancements in 3D printing, organ-on-chip technology, AI integration, monitoring devices, expanding beyond pharmaceuticals, and disease-specific model development.

What Main Forces Are Fueling Expansion In The In-Vitro Lung Model Market?

The growing number of clinical studies is expected to propel the growth of the in vitro lung model market. Clinical trials are essential for testing new medical treatments, and their increase is driven by the need for more advanced healthcare solutions. In vitro lung models help researchers test treatments and understand disease mechanisms. According to ClinicalTrials.gov, the number of registered clinical trials reached 477,230 in 2023, showing a growing focus on medical research.

What Are The Primary Segments In The Global In-Vitro Lung Model Market?

The in-vitro lung model market covered in this report is segmented –
1) By Type: Two-Dimensional (2D) Model, Three-Dimensional (3D) Model
2) By Application: Drug Discovery And Toxicology Studies, Physiological Research, Three-Dimensional (3D) Model Development, Other Applications
3) By End-User: Academic Research Institutes, Pharmaceutical And Biotechnology Companies, Other End-Users Subsegments:
1) By Two-Dimensional (2D) Model: Monolayer Cell Cultures, Co-cultures
2) By Three-Dimensional (3D) Model: Spheroids, Organoids, Lung-On-A-chip Models

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What Emerging Trends Are Influencing The Growth Of The In-Vitro Lung Model Market?

In the invitro lung model market, key players are making significant advancements by creating 3D models of respiratory tissues to improve the significance and intricacy of their models. These 3D recreations of respiratory tissues are made by nurturing chosen respiratory cells in a unique environment that enables them to form a three-dimensional structure. This mimics the functionality and form of the respiratory system, providing a more believable platform for research and drug testing. A case in point, MatTek Corporation, a renowned biotechnology firm in the US, announced the release of EpiNasal in April 2023. This revolutionary 3D model of respiratory tissue is made using primary human nasal epithelial cells. It accurately copies the 3D structure and operations of nasal epithelium, comprising mucus-making goblet cells, functioning tight junctions, and beating cilia. With EpiNasal, MatTek aims to extend its range of 3D lung tissue models. This state-of-the-art model provides an all-inclusive framework to study the impact of drugs, chemicals, pathogens, and consumer goods on the human respiratory system.

Who Are the Key Players In The In-Vitro Lung Model Market?

Major companies operating in the in-vitro lung model market are:
• Thermo Fisher Scientific Inc.
• Lonza Group AG
• PerkinElmer Inc.
• Charles River Laboratories International Inc.
• Varian Medical Systems Inc.
• Epithelix
• The Charles Stark Draper Laboratory Inc.
• STEMCELL Technologies
• American Type Culture Collection (ATCC)
• BioIVT
• InSphero
• Emulate Inc.
• PhoenixBio Co. Ltd.
• Newcells Biotech
• CN Bio Innovations Ltd.
• Mimetas
• Cyfuse Biomedical K.K.
• 3D Biotek LLC
• AlveoliX AG
• AxoSim Technologies LLC
• Elveflow
• Hesperos Inc.
• Kugelmeiers Ag
• SynVivo Inc.
• VITROCELL Systems GmbH

What Is The Most Dominant Region In The In-Vitro Lung Model Market?

North America was the largest region in the in-vitro lung model market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the in-vitro lung model market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.