The pharmaceutical intermediates market has seen considerable growth due to a variety of factors.
•In recent times, the market size of pharmaceutical intermediates has displayed robust growth. Its size is forecasted to escalate from $33.37 billion in 2024 to around $35.35 billion in 2025, reflecting a compound annual growth rate (CAGR) of 5.9%.
Factors such as advancements in chemical synthesis, the evolution of drug development, market demand and expansion, research and innovation, and adherence to regulatory standards have contributed to this growth in the historic period.
The pharmaceutical intermediates market is expected to maintain its strong growth trajectory in upcoming years.
• In the coming years, the market size of pharmaceutical intermediates is predicted to experience robust growth. The value is projected to escalate to $47.01 billion by 2029, with a compound annual growth rate (CAGR) of 7.4%.
This growth during the forecast period can be linked to advancements in biopharmaceuticals, the progression of precision medicine, initiatives in green chemistry, tailored intermediates and trends in pharmaceutical outsourcing. Key trends to look out for in this span include the constant flow of chemistry, the rise in automation and robotics, the use of nanotechnology, developments in biocatalysis and enzyme engineering, and strategic management of supply chains.
The surge in chronic illnesses is anticipated to fuel the expansion of the pharmaceutical intermediates market in the future. Chronic diseases, which are illnesses or conditions that generally last for three or more months and possess the risk of worsening over time, result predominantly from aging, lifestyle modifications, swift urbanisation, and absence of prevention strategies. Pharmaceutical intermediates are integral in the creation and manufacturing of drugs used for chronic disease management. For example, the National Institute of Health, a medical research institution based in the United States, stated in March 2022 that the incidence of chronic kidney disorders will reach 13.4%. Furthermore, it is estimated that between 4.902 and 7.083 million people will need renal replacement therapy due to advanced kidney disease (ESKD). The correct usage of pharmaceutical intermediates is crucial in reducing the growing incidence of these chronic conditions. Consequently, the escalation in the prevalence of chronic diseases is propelling the pharmaceutical intermediates market's growth.
The pharmaceutical intermediates market covered in this report is segmented –
1) By Product: Chemical Intermediate, Bulk Drug Intermediate, Other Products
2) By Category: Branded Drug Intermediate, Generic Drug Intermediate
3) By Application: Analgesics, Anti-Infective Drugs, Cardiovascular Drugs, Oral Antidiabetic Drugs, Antimicrobial Drugs, Other Applications
4) By End-User: Biotech And Pharma Companies, Research Institutions, Other End-Users
Subsegments:
1) By Chemical Intermediate: Active Pharmaceutical Ingredients (APIs), Specialty Chemicals
2) By Bulk Drug Intermediate: Precursor Chemicals, Intermediate Drug Substances
3) By Other Products: Biopharmaceutical Intermediates: Excipients, Pharmaceutical Additives
Leading enterprises in the pharmaceutical intermediates sector are creating fresh product lines like API Intermediates to heighten their market profitability. API intermediates are chemicals utilized in the creation of active pharmaceutical components or APIs. For example, in October 2023, an exciting new product series known as Gastrointestinal API Intermediates was unveiled by Huateng Pharmaceutical Co. Ltd., a company based in China. These intermediates serve as the foundation for the active constituents in digestive medications. They are essential for making medications used for treating gastrointestinal disorders, including 5-HT3 receptor antagonists, laxatives, H2-receptor antagonists, and proton pump inhibitors.
Major companies operating in the pharmaceutical intermediates market include:
• BASF SE
• Sanofi SA
• Thermo Fisher Scientific Inc
• Meck KGaA
• Dishman Carbogen Amcis Ltd
• Evonik Industries AG
• Arkema Inc.
• Lonza Group AG
• Wuxi AppTec co. Ltd
• Aurobindo Pharma Lmited.
• Lianhe Chemical Technology Co. Ltd.
• Cambrex Corporation
• Vertellus Holdings LLC.
• Hovione LLC
• Hikal Ltd.
• Codexis Inc.
• Aceto Corporation
• Interchem Corporation
• Midas Pharma GmbH
• Arbiom
• Dextra Laboratories Ltd.
• A. R. Life Sciences
• Ingenza Ltd
• Chiracon GmbH
• Dyadic International Inc.
• Elam Pharma Pvt Ltd
• Yin-sheng Bio-tech Co. Ltd.
• Green Vision Life Sciences
• Sibylla Biotech s.r.l.
• Pfizer CentreOne
North America was the largest region in the pharmaceutical intermediates market in 2024. The regions covered in the pharmaceutical intermediates market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.