The research-grade proteins market has seen considerable growth due to a variety of factors.
• The research-grade proteins market has experienced rapid growth in recent years. It is expected to grow from $1.11 billion in 2024 to $1.35 billion in 2025, at a compound annual growth rate (CAGR) of 21.4%.
The market's growth has been driven by increased research activities, rising investments in the pharmaceutical and biotechnology industries, demand for personalized medicine, and collaborations between government bodies, academic institutes, and private firms.
The research-grade proteins market is expected to maintain its strong growth trajectory in upcoming years.
• The research-grade proteins market is expected to grow rapidly, reaching $2.9 billion by 2029 at a CAGR of 21.2%.
The growth is driven by advancements in proteomics research, the increasing number of clinical trials, the integration of AI and data analytics, the use of research-grade proteins in industrial applications, and the rising demand for advanced research tools. Trends include growing awareness of innovative technologies, progress in biotechnology, advancements in proteomics and genomics, expanding applications in drug development, and the use of advanced research tools in biotechnology and pharmaceuticals.
The rise in the number of clinical trials is anticipated to fuel the expansion of the market for research-grade proteins. Clinical trials are research studies that evaluate the safety and efficacy of novel medical treatments, interventions, or devices on humans. Factors such as advancements in medical research, disease burden, regulatory changes, patient demand, and industry investment are leading to an increase in the number of these trials. Research-grade proteins play a crucial role in clinical trials as they serve as crucial resources for the development of biomarkers, assay development, identification of drug targets, quality control, and reference standards, which ensure the precision and dependability of experimental data. For example, data from ClinicalTrials.gov, a US clinical trial registry, showed that by the end of 2023, there were 477,234 clinical trials registered globally, an uptick compared to the 437,512 trials recorded in 2022. As a result, the surge in the number of clinical trials is propelling the expansion of the research-grade proteins market.
The research-grade proteins market covered in this report is segmented –
1) By Product: Cytokines And Growth Factors, Antibodies, Immune Checkpoint Proteins, Virus Antigens, Enzymes, Recombinant Regulatory Proteins, Hormones, Other Products
2) By Host Cell: Mammalian Cells, Bacterial Cells, Fungi And Yeast, Insect Cells, Other Host Cells
3) By End-Use: Pharmaceutical And Biotechnology Companies, Academic And Research Institute, Other End-Uses
Subsegments:
1) By Cytokines And Growth Factors: Interleukins, Interferons, Colony Stimulating Factors, Erythropoietin, Granulocyte Macrophage Colony-Stimulating Factor
2) By Antibodies: Monoclonal Antibodies, Polyclonal Antibodies, Recombinant Antibodies, Conjugated Antibodies
3) By Immune Checkpoint Proteins: PD-1 Inhibitors, PD-L1 Inhibitors, CTLA-4 Inhibitors
4) By Virus Antigens: HIV Antigens, Hepatitis Antigens, Influenza Antigens, Hepatitis B Antigens
5) By Enzymes: Restriction Enzymes, Proteases, Ligases, Kinases
6) By Recombinant Regulatory Proteins: Transcription Factors, Regulatory Enzymes, Epigenetic Modifiers
7) By Hormones: Insulin, Thyroid Hormones, Growth Hormones, Adrenaline
8) By Other Products: Peptides, Serum Proteins, Antigen-Binding Proteins
Key companies participating in the research-grade proteins industry are advancing their offering by developing Cas9 proteins, that proves pivotal for genome editing and a range of biotechnological applications. By acting as molecular scissors, Cas9 proteins can cut DNA at specific location identified by guide RNA (gRNA), thereby enhancing genome editing. In a recent development, Thermo Fisher Scientific Inc., a U.S. based biotech firm, in April 2022, has rolled out an advanced GMP-produced Gibco CTS TrueCut Cas9 Protein. Characterized by high-quality, clinical compliance and creation under Good Manufacturing Practice (GMP) conditions, this product is catered for genome editing operations. It provides high purity and versatility specifically designed for precise CRISPR-based research, paving the way for further innovation in genetic engineering and therapeutic evolution.
Major companies operating in the research-grade proteins market are:
• Thermo Fisher Scientific Inc.
• Bio-Rad Laboratories Inc.
• Bio-Techne
• Stemcell Technologies Inc.
• Miltenyi Biotec
• GenScript Biotech Corporation
• Sino Biological Inc.
• ACROBiosystems
• OriGene Technologies Inc.
• RayBiotech Inc.
• Rockland Immunochemicals Inc.
• Proteintech Group Inc.
• Novus Biologicals LLC
• Active Motif
• Aviva Systems Biology Corporation
• StressMarq Biosciences Inc.
• Abnova Corporation
• AnaSpec
• Biomatik
• Prospec-Tany Technogene Ltd.
• Cusabio Technology LLC
• United States Biological
• Laurus Bio
• Boster Biological Technology
• AMS Biotechnology Europe Ltd (AMSBIO)
North America was the largest region in the research-grade proteins market in 2023. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the research-grade proteins market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.