The saphnelo market has seen considerable growth due to a variety of factors.
• The market size of Saphnelo has been seeing a XX (HCAGR) growth in the recent past. From $XX million in 2024, it is projected to increase to $XX million in 2025, growing at a compound annual growth rate (CAGR) of XX%.
The factors contributing to this growth in the historic period include escalating healthcare spending, increased focus on research and development, a heightened emphasis on rare diseases, an increasing elderly population, and enhanced accessibility to healthcare services.
The saphnelo market is expected to maintain its strong growth trajectory in upcoming years.
• In the coming years, the market size of Saphnelo is projected to undergo considerable growth, exhibiting an XX% compound annual growth rate (CAGR). It is predicted to reach a valuation of $XX million by 2029.
The forecast period will see an increase due to factors such as increasing awareness and diagnosis, rising investment in biopharmaceuticals, broadening of patient assistance programs, elevated educational initiatives centred on lupus, advanced therapies, and a heightened demand for personalized medicine. The period of forecast will also be defined by trends such as the integration of AI into R&D, the introduction of innovative drug delivery systems, advancements in biologic manufacturing, emphasis on environment-friendly manufacturing practices, and the incorporation of telehealth for treatment supervision.
The escalating incidence of autoimmune diseases is posited to stimulate the growth of the Saphnelo market. Autoimmune diseases are conditions where the body's immune system erroneously attacks its tissues, construing them as harmful trespassers. This high incidence of autoimmune diseases can be traced back to factors such as hereditary propensity, external triggers, shifts in lifestyle, and heightened awareness. Saphnelo (anifrolumab) addresses these illnesses by targeting and inhibiting the type I interferon receptor, a pivotal component of the immune system frequently hyperactive in such circumstances, thereby alleviating inflammation and disease progression. For instance, a systematic examination of 464 studies in 2022, as reported by the US-based National Library of Medicine, uncovered 928 autoimmune condition instances linked to COVID-19 vaccination. Of these, 81.5% (756 cases) were newly occurring autoimmune diseases, with symptoms typically surfacing eight days following vaccination. Women made up 53.6% of the affected demographic, with a median age of 48. Thus, the growing occurrence of autoimmune diseases is fueling the expansion of the Saphnelo market.
The saphnelo market covered in this report is segmented –
1) By Indication: Systemic Lupus Erythematosus, Lupus Nephritis, Cutaneous Lupus, Systemic Sclerosis, Myositis
2) By Distribution Channe: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies
3) By End Use: Hospitals, Clinics, Ambulatory Care, Home Care
A prominent trend within the saphnelo market is the achievement of regulatory authorization for antibody-based remedies used in addressing autoimmune diseases. Regulatory approvals are essentially official permission from government or regulatory bodies permitting the public marketing and use of a drug, health device, or therapy. For instance, AstraZeneca Plc, a pharmaceutical company based in the UK, obtained approval from the European Union in February 2022 for its product, Saphnelo. Saphnelo (anifrolumab) is a novel type I interferon receptor antibody utilized as an additional therapy for systemic lupus erythematosus (SLE), which is moderately to severely active. This treatment helps reduce disease activity and reliance on oral corticosteroids. It is a substantial breakthrough as it's the first biologic in over ten years to not be limited to high disease activity, thus enhancing outcomes for SLE patients. The approval by the European Commission resulted from the Saphnelo clinical development program data, including evidence from the TULIP Phase III and MUSE Phase II trials. These clinical trials unveiled that more patients on Saphnelo had an overall reduction in disease activity across multiple organ systems and achieved a lasting reduction in oral corticosteroid use than those on a placebo.
Major companies operating in the saphnelo market are:
• AstraZeneca PLC.
North America was the largest region in the saphnelo market in 2024. The regions covered in the saphnelo market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.