The tangential flow filtration market has seen considerable growth due to a variety of factors.
• The market size of tangential flow filtration has experienced significant growth in the recent past. From a value of $1.41 billion in 2024, it is expected to rise to $1.58 billion in 2025, demonstrating a compound annual growth rate of 12.1%. The factors that have contributed to growth in previous years are expansion in the biopharmaceutical industry, increase in cell and gene therapy manufacturing, adherence to regulations, worldwide economic conditions, healthcare spending, broader use in vaccine production and an emphasis on drug safety and purity.
The Tangential Flow Filtration market is expected to maintain its strong growth trajectory in upcoming years.
• The market size of tangential flow filtration is predicted to experience swift expansion in the upcoming years. It is set to reach $2.74 billion in 2029, with a compound annual growth rate (CAGR) of 14.8%.
Factors contributing to the anticipated growth in the forecast period include recent advancements in mRNA vaccine production, increased use for exosome purification, enlargement of cell culture-based production, emphasis on scalability and flexibility, improvements in membrane chemistry, and surging application in nanoparticle separation. Key trends anticipated during the forecast period consist of research and development activities, adoption of single-use systems, advanced membrane technologies, high-throughput screening, gene and cell therapy, intensification of bioprocesses, technological integration, as well as contract manufacturing organizations (CMOs).
The escalation in research and development (R&D) expenditure in the biotechnology and pharmaceutical sectors is anticipated to drive the tangential flow filtration market's progress. Tangential flow filtration (TFF) is commonly used in downstream processing of biopharmaceutical products, playing a significant role in concentration and process abilities. The growth of the market will be supported by the increase in R&D expenditure. For example, GOV.UK, a UK government department, reported in July 2024 that businesses invested £9.0 billion ($11.7 billion) in pharmaceutical R&D in 2022, equivalent to 0.36% of the UK's GDP. With pharmaceutical R&D representing 18% of all R&D conducted by businesses in the UK, it maintains the highest proportion across all products. Therefore, the growth in R&D spending is likely to stimulate demand for the tangential flow filtration market in the upcoming period.
The tangential flow filtration market covered in this report is segmented –
1) By Product: Reusable Systems, Single-Use Systems, Membrane Filters
2) By Technology: Ultrafiltration, Microfiltration, Reverse Osmosis
3) By Application: Bioprocess Applications, Viral Vector, Vaccine Purification, Other Applications
Subsegments:
1) By Reusable Systems: Crossflow Filtration Systems, Automated Tangential Flow Systems, Batch Systems
2) By Single-Use Systems: Pre-sterilized Single-Use Assemblies, Disposable Filter Capsules, Single-Use Bioreactors
3) By Membrane Filters: Ultrafiltration Membranes, Microfiltration Membranes, Nanofiltration Membranes, Reverse Osmosis Membranes
Leading companies in the tangential flow filtration market are concentrating their efforts on developing inventive solutions, like tangential flow filtration cassettes aimed specifically at laboratory use. These advanced tools increase efficiency and accuracy in bioprocessing applications. Tangential flow filtration cassettes designed for laboratory use are unique devices employed for the tangential flow filtration method. For example, in September 2024, Sartorius AG, a major Germany-based pharmaceutical and laboratory equipment provider, launched Vivaflow SU, an advanced version of the tangential flow filtration cassette. The newly introduced TFF system can accommodate input volumes from 100 mL to 1,000 mL and is specifically designed for use in ultrafiltration and diafiltration processes. This user-friendly cassette facilitates easy setup, eliminates the need for complex adjustments, and is compatible with standard laboratory pumps. It features an eco-conscious design that uses sustainable materials and 30.5% less plastic compared to earlier models, thereby reducing its environmental footprint.
Major companies operating in the tangential flow filtration market include:
• Danaher Corporation
• Koch Membrane Systems Inc.
• Merck Millipore
• Sartorius AG
• GE Healthcare
• Parker Hannifin Corporation
• Repligen Corporation
• Alfa Laval Corporate AB
• Andritz AG
• Sterlitech Corporation
• Meissner Filtration Products Inc.
• Spectrum Inc.
• TangenX Technology Corporation
• Watersep Bioseparations Corporation
• Pall Corporation
• Novasep Holding SAS
• Asahi Kasei Corporation
• Graver Technologies
• GEA Group Aktiengesellschaft
• Filtration Group Corporation
• 3M Company
• Amazon Filters Ltd.
• Advantec MFS Inc.
• Membrane Solutions LLC
• Entegris Inc.
North America was the largest region in the tangential flow filtration market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the tangential flow filtration market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.