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Global Ultomiris Overview 2025, Forecast To 2034

11 Mar, 2025

What Fueled The Previous Growth In The Ultomiris Market?

The ultomiris market has seen considerable growth due to a variety of factors.
• In recent years, the market size of Ultomiris, indicated by XX (HCAGR), has seen significant expansion. The market is projected to grow from a value of $XX million in 2024 to $XX million in 2025, indicating a compound annual growth rate (CAGR) of XX%.
This growth can be traced back to several factors including the escalating prevalence of chronic ailments, expanding demand for biologics, a rise in the applications of mAb therapies, a surge in cases of autoimmune conditions, as well as the growing incidence of PNH.

What Can Be Expected from the Ultomiris Market Size?

The ultomiris market is expected to maintain its strong growth trajectory in upcoming years.
• Predictions indicate a XX (FCAGR) increase in the Ultomiris market size in the years to come. The market is expected to reach a value of $XX million by 2029, growing at a Compound Annual Growth Rate (CAGR) of XX%.
This growth over the forecast time is attributed to factors such as increased strain on healthcare systems, a rise in arthritis and inflammatory diseases incidence, growing investment in research, a higher number of drug approvals, and increased cases of musculoskeletal disorders. Noteworthy trends during the forecast period include enhancement of hospital infrastructure, advancements in treatment options, strategic collaborations in the research sector, the invention of orphan drugs, and branching out into new indications.

What Are the Critical Driver Fuelling The Ultomiris Market's Growth?

The expanding incidence of autoimmune disorders is anticipated to further growth in the ultomiris market. These disorders, whereby the immune system mistakenly damages the body's own healthy cells and tissues, are becoming more common due to both environmental influences such as exposure to pollutants and chemicals and enhanced diagnostic procedures. More cases are now being identified and treated. The drug Ultomiris helps treat autoimmune disorders like Paroxysmal Nocturnal Hemoglobinuria (PNH) and Atypical Hemolytic Uremic Syndrome (aHUS) by blocking complement protein C5, thereby decreasing immune attacks on the body. For example, according to a June 2024 report by the Australian Institute of Health and Welfare, a governmental organisation based in Australia, there were 10,000 hospitalisations due to rheumatoid arthritis, an autoimmune disease, in 2022. This represented a 25% rise from 8,000 the previous year, with a hospitalisation rate of 39 per 100,000 people. Therefore, the growing incidence of autoimmune disorders is fuelling the expansion of the ultomiris market.

How Is The Ultomiris Market segmented?

The ultomiris market covered in this report is segmented –
1) By Indication: Paroxysmal Nocturnal Hemoglobinuria (PNH), Atypical Hemolytic Uremic Syndrome (aHUS), Generalized Myasthenia Gravis (gMG), Neuromyelitis Optica Spectrum Disorder (NMOSD)
2) By Formulation: Intravenous Solution, Subcutaneous Formulation
3) By Distribution Channel: Hospital And Clinics, Retail And Specialty Pharmacies
4) By End User: Adult Patients, Pediatric Patients

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Which Emerging Market Trends Are Altering The Ultomiris Industry?

A prominent trend in the Ultomiris market involves acquiring approval from regulatory bodies to broaden its therapeutic uses and market penetration. Regulatory approvals are validations that a new drug is safe, effective, and maintained quality control and are based on the clinical trial findings. For example, in March 2024, British pharmaceutical company AstraZeneca got the green light from the FDA for ULTOMIRIS (ravulizumab-cwvz) to be used in the treatment of adults diagnosed with Neuromyelitis Optica Spectrum Disorder (NMOSD) who are positive for the anti-aquaporin-4 (AQP4) antibody. The importance of this approval lies in ULTOMIRIS being the first long-lasting C5 complement inhibitor for NMOSD, which was evidenced to cut down the relapse risk by 98.6% in clinical tests. ULTOMIRIS is engineered to hinder immune attacks on the central nervous system by restraining the complement system. However, it's worth noting that it poses some risks, including severe meningococcal infections, and has regular side effects like headaches and urinary tract infections.

Who Are the Key Players In The Ultomiris Market?

Major companies operating in the ultomiris market are:
• AstraZeneca Plc.

What Is The Most Dominant Region In The Ultomiris Market?

North America was the largest region in the ultomiris market in 2024. The regions covered in the ultomiris market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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