The xenotransplantation market has seen considerable growth due to a variety of factors.
• Over the past few years, significant growth has been observed in the xenotransplantation market. The market size is predicted to expand from $14.68 billion in 2024 to $15.82 billion in 2025, signaling a compound annual growth rate (CAGR) of 7.8%.
This notable growth during the historical timeline can be traced back to the rising demand for organ transplants, advancements in animal breeding, clinical trials, regulatory approval processes, and surgical procedures.
The xenotransplantation market is expected to maintain its strong growth trajectory in upcoming years.
• The xenotransplantation market is forecasted to experience strong expansion in the upcoming years. The market is projected to increase to $21.98 billion by 2029, with a compound annual growth rate (CAGR) of 8.6%.
Factors contributing to this growth in the forecasted period range from global healthcare infrastructure and public funding to telemedicine, public perception and acceptance, and AI utilization. Key trends expected to emerge during the forecast period include personalized xenotransplantation, multi-organ transplants, amalgamation with precision medicine, long-term patient tracking solutions, and the application of blockchain technology.
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The xenotransplantation market is anticipated to thrive due to surging demand for tissue and organ transplantation. Genetic disorders such as cystic fibrosis, polycystic kidney disease, or cardiac malfunctions could contribute to the need for organ transplantation in a considerable patient population. The acute demand for organ transplants is associated with an organ shortage, a situation xenotransplantation seeks to alleviate by replacing human organs with nonhuman ones. For example, the United Network for Organ Sharing, a nonprofit scientific and educational institution based in the U.S, disclosed that the U.S. performed 42,887 organ transplants in 2022, resulting in a 3.7 percent increment from 2021 and reaching a new yearly high in January 2023. Consequently, the escalating demand for tissue and organ transplantation will stimulate the xenotransplantation market's growth.
The xenotransplantation market covered in this report is segmented –
1) By Products: Organ Preservation Solutions, Transplant Diagnostics, Tissue Products
2) By Treatment: Analgesic, Immunosuppressant, Other Treatments
3) By Applications: Heart, Kidney, Other Organs
4) By End-Users: Hospitals, Transplant Centers, Other End-Users
Subsegments:
1) By Organ Preservation Solutions: Hypothermic Preservation Solutions, Normothermic Preservation Solutions, Organ Storage Solutions
2) By Transplant Diagnostics: Pre-Transplant Compatibility Testing, Post-Transplant Monitoring, Molecular Diagnostics
3) By Tissue Products: Xenograft Tissue Products, Tissue Engineered Products, Biological Scaffolds
Significant players in the xenotransplantation market are incorporating emerging technologies like preservation technology to enhance organ maintenance methods and efficiency. Preservation technology covers an array of methods and tools used to safeguard and uphold the value of vital objects, data, or environments over a period. For example, in January 2022, a medical technology company based in Sweden, XVIVO, which is dedicated to the development of optimized solutions for organ, tissue, and cell preservation, debuted a novel strategy for effectively storing and transporting donor hearts. Presently, the transplant sector grapples with the issue of organ deficit. Therefore, a limited number of patients with end-stage heart disease get the opportunity for a transplant, with a considerable number dying while waiting for a new organ. Xenotransplantation, the act of transplanting across different species, offers a potential solution to this dire shortage. A recent landmark study using XVIVO's heart preservation technology achieved extended survival following the xenotransplantation of gene-edited pig hearts into primates.
Major companies operating in the xenotransplantation market include:
• Novartis AG
• Astellas Pharma
• United Therapeutics
• Preservation Solutions
• OrganOX Limited
• Talaris Therapeutics
• TransMedic Inc.
• Sernova Corp
• Nova Lung
• Recombinetics
• Tissue Regenix
• TissueGene
• SAB Biotherapeutics
• eGenesis
• Revivicor
• Organ Recovery Systems
• CRISPR Therapeutics
• Qihan Biotech
• Sino-Clone Organ Biotechnology
• Xenothera
• Lung Biotechnology.
North America was the largest region in the xenotransplantation market in 2024. The regions covered in the xenotransplantation market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.