The hydrolase enzymes market has seen considerable growth due to a variety of factors.
• In recent times, the market size for hydrolase enzymes has seen considerable growth. The market is projected to expand from $6.47 billion in 2024 to $6.96 billion in 2025, with a compound annual growth rate (CAGR) of 7.6%. Key factors contributing to this growth during the historical period include biotechnological advancements, increasing demand for sustainable solutions, research and development efforts, its industrial use in food processing, and its growing role in the production of biofuels.
The Hydrolase Enzymes market is expected to maintain its strong growth trajectory in upcoming years.
• The market for hydrolase enzymes is predicted to experience considerable expansion in the coming years, with projections putting it at $9.56 billion by 2029, emphasizing a compound annual growth rate (CAGR) of 8.3%.
Factors such as the increase in biofuel and bioenergy production, advancements in enzyme engineering, a surge in industrial biotechnology, expanded use in personal care products, and growth in bioremediation and waste management contribute to the forecasted expansion. Other significant trends for the forecast period consist of exploration of microbial diversity, extending applications in the food industry, the customization of processes through protein engineering, a concentration on sustainable biocatalysis, and the ongoing development of biopharmaceuticals.
An increase in instances of pancreatitis is anticipated to stimulate the expansion of the hydrolase enzymes market in the near future. The term pancreatitis is used to describe a condition where inflammation occurs in the pancreas glands, causing intense abdominal discomfort. The condition may be temporary (acute) or it could last a lifetime (chronic). Valued hydrolase enzymes, such as pancreatic lipase, amylase, and protease, are employed to address malabsorption linked to pancreatic insufficiency caused by pancreatitis and cystic fibrosis. Here, these enzymes work by catalyzing the reaction of triacylglycerol and water, producing diacylglycerol and a fatty acid anion, initiating the digestion of dietary fats and addressing pancreatic exocrine insufficiency. In December 2022, UpToDate, Inc., a US organization offering subscription-based access to up-to-date clinical information to physicians, reported that the yearly incidence of acute pancreatitis in the US varied from 4.9 to 35 per 100,000 individuals due mainly to increased rates of obesity and gallstones. Therefore, the growing prevalence of pancreatitis is fuelling the expansion of the hydrolase enzymes market.
The hydrolase enzymes market covered in this report is segmented –
1) By Product: Esterase, Glycosylases, Peptidases, Other Products
2) By Bond Type: Ester Bonds (Esterases), Sugars (DNA Glycosylases And Glycoside Hydrolase), Ether Bonds (Thioether And Trialkylsulfonium), Peptide Bonds (Peptidases), Carbon-Nitrogen Bonds (Other Than Peptide Bonds), Acid Anhydrides, Carbon-Carbon Bonds, Halide Bonds, Phosphorus-Nitrogen Bonds, Other Bond Types
3) By Application: Pharmaceutical, Food And Beverages, Laundry Detergents, Cosmetics, Textile, Pulp And Paper, Biofuel, Other Applications
Subsegments:
1) By Esterase: Acetylcholinesterase, Lipases, Carboxylesterases
2) By Glycosylases: Amylases, Cellulases, Glucosidases
3) By Peptidases: Serine Peptidases, Cysteine Peptidases, Aspartic Peptidases, Metallopeptidases
4) By Other Products: Phosphatases, Nucleotidases, Other Hydrolases
Product innovation is a significant trend that is progressively rising in the markets for hydrolase enzymes. Major corporations in the hydrolase enzyme market are launching revolutionary products to maintain their market influence. For instance, Biocatalysts Ltd, a biotech firm in the UK that manufactures specialty enzymes, has recently introduced Promod 517MDP (P517MDP) - an enzyme tailored for dairy protein. P517MDP is an exceptionally efficient exopeptidase that can hydrolyse over 40% of casein protein into smaller fragments like peptides and amino acids. These components can then be leveraged in the manufacture of special medical purpose foods (FSMP*), such as specialised infant and follow-on formulas, thereby enhancing its solubility and digestive ease.
Major companies operating in the hydrolase enzymes market include:
• Creative Enzymes Holdings Limited
• Advanced Enzyme Technologies Limited
• Specialty Enzymes & Probiotics
• Novozymes A/S
• Antozyme Biotech Private Limited
• Infinita Biotech Private Limited
• Aumgene Biosciences (Shanghai) Co. Ltd.
• AB Enzymes GmbH
• Dyadic International Inc.
• Sisco Research Laboratories Pvt Ltd.
• Amano Enzyme Inc.
• Codexis Inc.
• Merck KGaA
• BESTZYME BIO-ENGINEERING CO. Ltd.
• Bioseutica Group
• BASF SE
• Kemin Industries Inc.
• Epygen Labs FZ LLC
• DuPont de Nemours Inc.
• Biovet Private Limited
• Enzyme Development Corporation
• Associated British Foods
• Chr. Hansen Holding A/S
• Thermo Fisher Scientific Inc.
• Koninklijke DSM N.V.
• Enzymes Biotec Limited
• Kerry Group plc
North America was the largest region in the hydrolase enzymes market in 2024. Europe is expected to be the fastest-growing region in the hydrolase enzymes market report during the forecast period. The regions covered in the hydrolase enzymes market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa