Biologics Industry Overview

CAR-T Therapy Market Definition

The chimeric antigen receptor -T therapy market consists of sales of CAR-T therapy products and related services by entities (organizations, sole traders and partnerships) that develop chimeric antigen receptor (CAR) T-cell therapies to treat blood cancers. CAR-T therapy is type of immunotherapy in which T-cells taken from patient’s blood are modified in a laboratory with the addition of a special protein receptor that grants T-cells the power to recognize as well as kill cancer cells easily, along with infusing the same back into that patient. This special protein receptor, known as the chimeric antigen receptor (CAR), attaches to a specific protein on a patient’s cancer cells. The infused cells multiply and prevail in the patient’s body as living drugs. This industry includes establishments that are involved in the research and development to introduce new targeted cell therapies for treating indications related mostly to hematological malignancies. However, some of the pipeline CAR-T therapies are aimed at targeting solid tumors including pancreatic cancer, breast cancer, ovarian cancer, gastric cancer, kidney cancer, brain tumor, and other cancer types.

Vaccines Market Definition

The vaccines market consists of sales of vaccines and related services by entities (organizations, sole traders and partnerships) that produce vaccines to prevent various diseases. Vaccines are biological preparations that stimulate the immune system and prepare it to fight future infections caused by pathogens. They trigger the production of antibodies against pathogens or any foreign matter that enters the body. Vaccines can be administered orally, through injections or by aerosol. Vaccine doses are administered to both children (pediatric vaccines) and adults based on the schedule set for each vaccine. For adults, the vaccines are recommended based on age, health condition, prior vaccinations and occupation. The vaccines market is segmented into anti-infective vaccines; anti-cancer vaccines; and other-vaccines. Only goods and services traded between entities or sold to end consumers are included. Vaccines are preventative medicines which are administered to the general population or to those vulnerable in a population as a precautionary measure to combat a disease, they may include single or multiple doses. Vaccines work by mimicking the infectious bacteria or virus that cause a disease. They energize the body’s immune system to build up a defensive mechanism against the infectious virus or bacteria without causing the disease. Vaccines contain weakened versions of bacteria or virus, and some contain only part of the bacteria or virus. Specific vaccines also contain only the genetic material for a specific protein which directs the body to produce similar type of protein.

Pediatric Vaccine Market Definition

The pediatric vaccine market consists of sales of pediatric vaccines and related services used to provide immunity to infants and children from birth to 18 years of age for specific diseases. Pediatric vaccines are a preparation of dead microorganisms, live attenuated organisms, or fully virulent organisms that are administered to stimulate the production of antibodies and provide immunity against one or several diseases among children. Pediatric vaccines are used in childhood immunization schedules to enhance a child’s immunity or prevent diseases such as diphtheria, tetanus, pertussis, influenza, Hepatitis B, polio, and many other infectious and non-infectious diseases. The market by value in this report is defined as the revenues that enterprises gain from goods and/or services within the specified market and geography. It does not include revenues from resales of goods and services such as media rights, and merchandise either further along the supply chain or as part of other products. Only goods and services traded between entities or sold to end consumers are included. Whether specifically stated or not, the markets for goods include related services and the markets for services include related goods.

Antisense & RNAi Therapeutics Market Definition

The antisense and RNAi therapeutics market consists of sales of antisense and RNAi therapeutics by entities (organizations, sole traders, and partnerships) that develop and manufacture antisense and RNAi therapeutics to treat various diseases. RNA interference (RNAi)-based and RNA-based antisense oligonucleotide therapies are advanced methods used for the treatment of various diseases including cancer, infectious diseases, cardiovascular diseases, genetic disorders, respiratory disorders, and neurological disorders. Two major methods are employed in RNA therapeutics: double stranded RNA-mediated interference (RNAi) and antisense oligonucleotides (ASO). Both these methods differ in composition and modes of action. These antisense oligonucleotides and siRNAs mainly target the ribonucleic acid (RNA), whereas small molecules and biologic drugs primarily target proteins due to their chemical properties and distinct molecular mechanism of action.

Telemedicine Services Market Definition

The telemedicine services market consists of sale of telemedicine services and related products. Telemedicine services are healthcare services provided via video chats, phone calls, and text messages. Patients can use telemedicine for physical examinations as well as to ask questions regarding health concerns. Telemedicine services are offered by healthcare professionals via various information and communication technologies with the aim of exchanging valid information for the diagnosis, treatment and prevention of diseases and injuries in patients where distance is a critical factor.

Human Microbiome Therapeutics Market Definition

The human microbiome therapeutics market consists of sales of microbiome and related services used as immunotherapeutic agents in the pharmaceutical industry. Microbiomes are used as immunotherapy for a wide variety of conditions, including infectious diseases, endocrine & metabolic disorders, inflammatory conditions, cancers, irritable bowel syndrome, neurological disorders, hematological disorders and cardiovascular diseases. The microbiome consists of the genetic material within a microbiota, which is the collection of microorganisms, such as bacteria, archaea, fungi, and viruses, in a specific niche, such as the human gut. For example, the gut microbiome consists of collective genome of microbes inhabiting the gut. Microbiomes are also known as the metagenome of the microbiota.

Biologics Market Definition

The biologics market consists of sales of biologics and related services by entities (organizations, sole traders and partnerships) that produce biologics or biosimilars to treat and prevent various microbial diseases and cancers. The biologics market comprises companies manufacturing biological products that are derived from genetically modified proteins and human genes. Biologics products include a wide range of recombinant therapeutic proteins, gene therapy tissues, somatic cells, vaccines, and allergenics. Biologics products are subjected to various laws and regulations that deal with patenting, testing, safety, efficacy and marketing. Biologics products are isolated from natural sources such as human, animal, and microorganisms by biotechnological methods and other cutting-edge technologies. Biosimilars should have similar safety and efficacy compared to the reference biologic product. The biologics market comprises of biologics and biosimilar drugs through oral, IV and other delivery routes for the treatment of chronic diseases.

Oral Biologics & Biosimilars Market Definition

The oral biologics and biosimilars market consist of sales of oral biologics and biosimilar products and related services used to treat chronic diseases such as diabetes, arthritis, and cancer. Biologics are drugs made from living cells using highly complex technology, while biosimilars are biological products which are being produced to be identical to a biologic already approved, known as reference drugs. Biosimilars should have similar safety and efficacy compared to the reference biologic product. The oral biologics and biosimilar market comprise of biologics and biosimilar drugs through oral delivery route, for the treatment of chronic diseases.